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Carolina Parada-Borja

@caroparadab

Developmental biologist studying how embryos build limbs. Permanent researcher at J. Gros lab, Institut Pasteur.

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01.09.2023
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Latest posts by Carolina Parada-Borja @caroparadab

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧡 (carried over from the old place)

28.02.2026 08:12 πŸ‘ 372 πŸ” 152 πŸ’¬ 16 πŸ“Œ 16
National Academies of Sciences, Engineering, and Medicine logo. Academia Brasileira de Ciencias logo. Connections to sustain science in Latin America Symposium 2026. August 25-27, 2026. SΓ£o Paulo, Brazil. Session Topics (Bulleted List): Artificial Intelligence in the Life Sciences, Oceans, Biomedicine & Omics, The Amazon & Sustainability, and Resilience in Extreme Events. Apply by April 15, 2026. QR code.

National Academies of Sciences, Engineering, and Medicine logo. Academia Brasileira de Ciencias logo. Connections to sustain science in Latin America Symposium 2026. August 25-27, 2026. SΓ£o Paulo, Brazil. Session Topics (Bulleted List): Artificial Intelligence in the Life Sciences, Oceans, Biomedicine & Omics, The Amazon & Sustainability, and Resilience in Extreme Events. Apply by April 15, 2026. QR code.

Apply now: Connections to Sustain Science in Latin America Symposium 2026 in SΓ£o Paulo (Aug 25–27).

For early/mid-career researchers across the Americas. Travel fully funded.

Apply by Apr 15: https://ow.ly/ZzMy50Yqb4i

#NASEMCapacity #LatinAmerica #LAConnections

06.03.2026 22:00 πŸ‘ 9 πŸ” 7 πŸ’¬ 2 πŸ“Œ 0
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πŸ”¬βœŠ One year later, we #StandUpForScience again.

Attacks multiply. Funding shrinks. But our determination doesn't.

Science isn't opinion, it's the foundation of democracy.

Institut Pasteur researchers are mobilizing. Join us.

#StandUpForScience2026 #ScienceMatters #ResearchMatters

06.03.2026 16:01 πŸ‘ 58 πŸ” 30 πŸ’¬ 0 πŸ“Œ 0
Le rassemblement Stand Up for Science Γ  l’institut Pasteur

Le rassemblement Stand Up for Science Γ  l’institut Pasteur

One year after, we Stand Up for Science one more time at @pasteur.fr
#StandUpForScience
@standupforscifr.bsky.social
✊

06.03.2026 12:43 πŸ‘ 122 πŸ” 26 πŸ’¬ 0 πŸ“Œ 2
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Tissue phase transitions in development: more than just mechanics Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...

Tissue phase transitions in development: more than just mechanics url: journals.biologists.com/dev/article-...

13.02.2026 12:46 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Most of the principal investigators in the PRBB are women - ElΒ·lipse The upward trend of previous years continues, with women now holding 51% of senior positions in research groups.

🟣 Today, on the International Day of Women and Girls in Science ( #11February), we’re excited to share a milestone:
women PIs are now the majority at the #PRBB for the first time.

1/6 #WomenInSTEM #SomPRBB

11.02.2026 13:09 πŸ‘ 6 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0

Ancient origin of the dorso-ventral patterning system of vertebrate paired fins https://www.biorxiv.org/content/10.64898/2026.02.08.704681v1

10.02.2026 17:30 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Actin and myosin dynamics during epithelial remodeling in avian gastrulation Epithelial remodeling is powered by contractile forces exerted by the actomyosin cytoskeleton. In invertebrates, pulsatile contractile flows of the medio-apical actomyosin cortex have been shown to be...

I’m pleased to share our latest preprint (my first as 1st-author) from JΓ©rΓ΄me Gros’ group (@jeromegros.bsky.social), now on bioRxiv. It reports actin and myosin dynamics during epithelial remodeling in avian gastrulation. (doi: doi.org/10.64898/202...)

19.12.2025 16:33 πŸ‘ 13 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
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LimbLab: a tool to visualise development in 3D | EMBL Researchers at EMBL Barcelona have developed an open-source tool that makes working with complicated volumetric imaging data easier.

LimbLab: a tool to visualise development in 3D www.embl.org/news/science...

05.02.2026 10:13 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

πŸ₯³πŸ₯³πŸ₯³ Pretty fab start to 2026!!

19.01.2026 16:51 πŸ‘ 41 πŸ” 8 πŸ’¬ 6 πŸ“Œ 0

New publication : is left-right symmetry-breaking in mice in the node ?

06.01.2026 21:23 πŸ‘ 19 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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Preprints without borders: SciELO Preprints’ push for multilingual, Open Science in Latin America and beyond - preLights preLights recently spoke with Carolina Tanigushi who now looks after SciELO Preprints, the preprint server that is part of the SciELO Network. We talked about SciELO’s shift into an Open Science progr...

Preprints without borders 🌎

Carolina Tanigushi explains how @scielo.org & SciELO Preprints boost #OpenScience across Latin America & beyond, increase visibility for regional research + what (early-career) researchers can do to benefit.

Read the interview: prelights.biologists.com/news/preprin...

15.01.2026 11:27 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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🚨 PhD Position Available 🚨
I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), MΓΌnster, Germany.

www.bischofflab.com/jobs

Fully funded βœ…
#Cellbio #Morphogenesis #Microscopy
#Drosophila #PhD
(Details Below)

Original Posting:
stellen.uni-muenster.de/jobposting/d...

15.12.2025 12:20 πŸ‘ 44 πŸ” 36 πŸ’¬ 2 πŸ“Œ 4
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LimbNET, an open platform to visualise limb development - ElΒ·lipse A new open access platform for the limb development community will close the gap between experiments and mathematical models.

Want to discover LimbNET? 🦡

A platform created by EMBL Barcelona scientists to visualize limb development.

Explore the β€œMorphomovies”
πŸ‘‰ tuit.cat/M8Kjg

12.12.2025 12:10 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Register now for the EMBO Workshop "Limb development and regeneration: Quantitative, ecological, and diversification studies" in #Tokyo, Japan, 23–27 March 2026.

Abstract submission/Registration deadline:
12/15 December 2025

https://meetings.embo.org/event/26-limb-dev
#EMBOLimbDev #EMBOevents πŸ§ͺ

25.11.2025 16:10 πŸ‘ 15 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Hey everyone! I’m excited to share that one of my thesis projects was just published in @currentbiology.bsky.social and featured on phys.org! In this paper, we use an old statistical approach developed by the US Navy in WW2 to predict the aquatic habits of various dinosaurs and marine reptiles πŸ¦–πŸŠ

20.11.2025 20:51 πŸ‘ 85 πŸ” 27 πŸ’¬ 1 πŸ“Œ 3
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Neil Shubin (1) | Collège de France

The talks (in english) can be accessed from the @college-de-france.fr website. A great journey through β€˜Our ancestors the fish’, from 380 Mio years ago to their hidden presence inside ourselves. Lessons #1 and #2 πŸ‘‡πŸΌ
www.college-de-france.fr/en/agenda/gu...
www.college-de-france.fr/en/agenda/gu...

07.11.2025 15:49 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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The Friday crème brûlée is back! @institutpasteur.bsky.social

31.10.2025 16:34 πŸ‘ 21 πŸ” 4 πŸ’¬ 1 πŸ“Œ 2
This image is figure 3 from the paper showing the reconstructed left hand of the KNM-ER 101000 fossils.

This image is figure 3 from the paper showing the reconstructed left hand of the KNM-ER 101000 fossils.

A newly uncovered set of 1.5-million-year-old fossils that includes the first unambiguous Paranthropus boisei hand bones are reported in Nature. The findings offer insights into the evolution of hominin hands. go.nature.com/495cW1I πŸ§ͺ 🏺

16.10.2025 16:26 πŸ‘ 33 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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Dual Bmp-negative feedback loops modulate function of both AER and ZPA to buffer and constrain postaxial digit number | PNAS Several lines of evidence indicate that posterior (postaxial) digit number in tetrapod vertebrates is constrained to the pentadactyl state by inter...

transport yourself to the late 90s with this really cool paper on digit number regulation by Shh and BMP, ZPA and AER. www.pnas.org/doi/10.1073/...

26.09.2025 18:54 πŸ‘ 39 πŸ” 13 πŸ’¬ 3 πŸ“Œ 0
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We are hiring ! Interested in understanding how neuronal cell diversity arises? Come and join us @upf.edu for a #PhD #FPI fellowship

06.10.2025 12:59 πŸ‘ 10 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0
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The evolution of hominin bipedalism in two steps - Nature The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primatesβ€”...

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature -
www.nature.com/articles/s41...

27.08.2025 15:13 πŸ‘ 98 πŸ” 45 πŸ’¬ 7 πŸ“Œ 13
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How can cells self-organize rapidly into complex patterns during development?

Let’s explore a powerful and underappreciated mechanism: Directed Cell Migration (DCM).

Preprint @biorxivpreprint.bsky.social : doi.org/10.1101/2025...

πŸ‘‡Thread 🧡(1/11)

30.07.2025 07:00 πŸ‘ 53 πŸ” 18 πŸ’¬ 3 πŸ“Œ 4

A pivotal role for Wnt antagonists in constraining Wnt activity to promote digit joint specification. https://www.biorxiv.org/content/10.1101/2025.07.17.665381v1

21.07.2025 18:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Many thanks to Ruoheng Li and @prelights.bsky.social for featuring our preprint!

10.07.2025 17:08 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Schematics depicting the dorsal and ventral sides of fins and limbs

Schematics depicting the dorsal and ventral sides of fins and limbs

We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something β€œlike the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out πŸ‘‡πŸ§ͺ🧬🐟 doi.org/10.1101/2025...

07.07.2025 06:46 πŸ‘ 78 πŸ” 41 πŸ’¬ 11 πŸ“Œ 7

Muchas felicidades, Cristina! πŸ‘

03.07.2025 18:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

🚨 Early bird deadline: July 15th!

03.07.2025 11:34 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Human fingertip regeneration follows clinical phases with distinct proteomic signatures – a Comprehensive MS/MS analysis Distal injuries in human fingertips can regenerate almost fully, yet the process of human fingertip regeneration has hardly been characterized on a cellular and molecular level. A silicone finger cap,...

Preprint alert from our lab!
Human fingertip regeneration is not reserved for infants. Adults can regenerate with little to no scarring! We analysed wound fluids of patients during the course of regeneration and found that...

www.medrxiv.org/content/10.1...

25.06.2025 08:07 πŸ‘ 19 πŸ” 3 πŸ’¬ 3 πŸ“Œ 0

Changes in Evolutionary Developmental Control Points in the Amniote Limb May Explain Hyperphalangy academic.oup.com/mbe/article/...

17.06.2025 08:11 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0