Tom Driedonks

🆕New in #JEV🆕 Check out this editorial introducing @IsevOrg 's newest committee the ISEV Translation, Regulation and Advocacy Committee (ISEV-TRA). From Lab to Industry: Advancing the Translational Potential of Extracellular Vesicles isevjournals.onlinelibrary.wiley.com/doi/10.1002/...

⏰ Time is ticking!
📝 Abstract submission for #ISEV2026 closes on 13th January, 11.59 pm EST
✅ Remember, there will be NO LATE BREAKING abstract submission this year.
all info: www.isev.org/isev2026

@snevresearch.bsky.social

dear #fluorescentprotein specialists: anybody knows if mStaygold can be used in split complementation assays? Is analogy to the s11 strand split possible?

Happy to be at Science 4 Life today, showcasing great science from Utrecht's science park

Happy to present my latest research project at #NLSEV2025
Many interesting questions from the audience, so I guess I struck a chord 😉
Thanks to Luuk van de Schepop for the picture!
@nlsev.bsky.social

#NLSEV2025 PhD thesis awards!
Out of 5 entries, 2 theses reached the same score, and remained tied after adding 3 extra external reviewers.

Congratulations Marije Kuipers and Willemijn de Voogt!
@nlsev.bsky.social

Effortless cell targeting of EVs?
Sounds like an interesting keynote talk by Khuloud Al Jamal, #NLSEV2025
@nlsev.bsky.social

#NLSEV2025 are go!
Opening remarks by @esthernoltethoen.bsky.social and Agustin Enciso Martinez

Early Career Researcher Travel Grants for UKEV Forum 2025 - UK Society for Extracellular Vesicles Early-career research travel grants for UKEV Forum 2025 UKEV Travel Grants are available to help early career researchers (the applicants) attend and present their research at the UKEV Forum (15th to ...

Some travel grants for UKEV if there are any big UK extracellular vesicle fans out there!
🧪

www.ukev.org.uk/early-career...

Extracellular Vesicles and B Cell Interactions: B-Side Track or Greatest Hit? Substantial efforts have been made in understanding interactions between extracellular vesicles and cells, particularly in small animal models, such as rats and mice. However, many questions remain un...

Happy to have contributed to this perspectives article about interactions between therapeutic EVs and circulating B cells.
Unexpected discovery, confirmed in different experimental settings. Curious to learn more about these interactions and their therapeutic potential
pubs.acs.org/doi/10.1021/...

Abstract submitted for #NLSEV2025!
@nlsev.bsky.social

We don't know yet, it will take a while to process all of the samples. Luckily we don't have to do all of that in one day 😄

Had a 14h shift in the lab yesterday. Mice experiment followed by magnetic sorting of different cell types from tissues. Too many washing steps but there were some cells left in the end. Next step is to see whether my EVs have reached their destination 😅

We have some exciting news to share..... #JExBio is now indexed in Web of Science!!🎉🎉🎉

Yes! Mention of #extracellularvesicles in a @kurzgesagt.org popular science video about pregnancy. Wait until they learn about all the processes EVs play a role in 🤓

mGem: Guides or triggers? Extracellular RNAs beyond vesicular miRNAs | mBio Blood and other extracellular biofluids have a high RNase content. Hence, from its origins, the exRNA field has focused on extracellular vesicles (EVs) as the main carriers of RNA molecules that move ...

With @amyhbuck we wrote this piece on extracellular RNAs that intends not to give answers but to propose questions that can expand the field in new directions.

Hope you like it! We really enjoyed a lot brainstorming it.

journals.asm.org/doi/10.1128/...

😎 You can already submit your abstracts for #ISEV2026, in Puerto Rico!
🌴 Submit before 13th January 2026, there will be NO late breaking submission
www.abstractscorecard.com/cfp/submit/l...

Education Day 2025 Part 1: EVs. What are they? Where are they from? Where do they go? YouTube video by EVClub: Extracellular Vesicle Club

🎼 Did you know all #ISEV2025 Education Day Talks are on our YouTube channel?
🤩 Check out our playlist: youtu.be/ovtLcTMeyQU?...

do you ever stare at the ceiling and think about how the worldwide scientific establishment did the impossible and created a COVID vaccine in under a year and the response of the general public has been to go on an unstoppable rampage to destroy science and scientists

📢Call for papers!📢 #JExBio is pleased to announce its first Special Issue 'The Biomolecular Corona of Extracellular Vesicles'. Guest Edited by Professors Massimo Bottini, Benedetta Bussolati, and Annalisa Radeghieri. isevjournals.onlinelibrary.wiley.com/hub/journal/...

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

If you haven’t already, please consider signing & sharing this! NIH public servants defending the integrity of our publicly funded health research need our voices. This administration is
“damaging the hard-earned trust between the NIH, academia, & the public that is essential for long-term progress”

Very cool findings but kit-based 'exosome' isolation kits, like used in this paper, isolate many other things in culture medium. It would be good to validate this on a proper (density gradient or size-exclusion) EV isolate

🚨 EV Fundamental Biology Series: The 'dark matter' RNA of Extracellular Vesicles

This June 12th, join us for a relevant talk on the vesicular RNA topic!

Extracellular exosomal RNAs are glyco-modified - Nature Cell Biology Sharma, Jiao and colleagues report glycosylation of small RNAs within exosomes and propose a glycosylation-dependent mechanism for RNA targeting into exosomes, which may influence intercellular commun...

More insights into #glycoRNA, this time found within exosomes!

www.nature.com/articles/s41...

I'll do that! I noticed your thesis cover on the wall of the department, with the pelican and the ice cube. It's a small world after all!

Modulating binding affinity of aptamer-based loading constructs enhances extracellular vesicle-mediated CRISPR/Cas9 delivery - PubMed The CRISPR/Cas9 toolbox consists of modular nucleases that can be employed to efficiently modify genomic sequences with high specificity. However, delivery of the large Cas9-sgRNA ribonucleoprotein (R...

Happy to have contributed to this paper by @olivier-de-jong.bsky.social!
A proper balance of loading versus unloading of Cas9 RNPs is needed for effective gene editing ⚖️
pubmed.ncbi.nlm.nih.gov/40393529/
Congratulations to all co-authors!

📢 Come be a part of the SNEV team!

We’ve got 3 exciting positions open:
1️⃣ Media Team (1 position)
2️⃣ Podcast Team (2 positions)

🗓️ Deadline to apply: May 31st
⏳ Don’t miss your chance to make an impact. Apply NOW!
📩 Link in the Linktr.ee in our bio

I deep fried two of my SDS PAGE gels today but my most important samples were on gel nr 3 so things are going quite well today 🫠

Personalized gene editing! What a time to be alive

Inhibition of acid or neutral sphingomyelinases differentially impacts RNA and protein cargo sorting to extracellular vesicles Extracellular vesicles (EVs) form through regulated biogenesis processes involving sphingomyelinases (SMases), enzymes that metabolize sphingomyelin t…

Pretty cool study showing the effect of acid sphingomyelinase on non-coding RNA cargo of MCF-7 EVs.
Big changes in 'miscRNAs' 7SL and Y3 RNA, and functional effects in wound healing
www.sciencedirect.com/science/arti...