Check out my contribution to the wonderful threads posted by @epimechfc.bsky.social !!
In this one I talk about #3DTFM!
π
Check out my contribution to the wonderful threads posted by @epimechfc.bsky.social !!
In this one I talk about #3DTFM!
π
We had covered the history of traction force microscopy (TFM) earlier:
bsky.app/profile/epim...
But what about applying TFM into more physiologically relevant systems, such as those in 3D?
I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.
Tissue mechanics and synth morphogenesis folks, bump on this:
Would you or someone in your lab be up for a video of a protocol you use getting recorded? The tips and tricks, the hard-to-explain-without-seeing-it-done?
In the name of standardization and reproducibility in the field: get in touch! π«
Beautiful threadπ about Flipper from @juanmagararc.bsky.social #EpithelialMechanics
Hello epithelial mechanics fans!! Iβm Juanma @juanmagararc.bsky.social π I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells.
Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!
Epithelial Mechanics Fan Club @epimechfc.bsky.social is top-fin #scicomm, in case you haven't heard of it!
Follow them for more like this thread posted by Knaut Lab member and #zebrafish lateral line guru, @weiyiqian.bsky.social π
PhD job alert! π¨Interested in epithelial mechanics and bacterial infection? Do you have a computational background? Donβt miss this opportunity!
Details in thread π§΅π
#AcademicJobs #PhDPosition #Biomechanics
Please RT π¬π» @epimechfc.bsky.social @unizar.es @i3a.unizar.es @esbiomech.bsky.social
How can structures at the vertex of 3 cells have effects at the tissue level?
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. π§΅β€΅οΈ doi.org/10.1126/scie...
Lobbying in Albany with @uaw.org and @cpw-uaw4100.bsky.social for the Empire Biomedical Research Institute. Learn more:
@fundnyscience.bsky.social.
How does a uniform zygote reliably break symmetry?
How do initially identical cells diverge in cell-cycle timing and transcriptional state?
In our new paper in Nature Physics, we show that embryo geometry itself is sufficient to pattern early development.
www.nature.com/articles/s41...
How can embryos use pulsatile contraction to shape tissue development during morphogenesis? I'm @weiyiqian.bsky.social and with this thread I want to introduce the roles of pulsatile actomyosin in animal development and the mechanisms that drive actomyosin to pulse
Very nice new preprint from the lab!
Congrats @yuieda1.bsky.social @jeromegros.bsky.social
Congratulations to Byung Ho from the @anne-grapin.bsky.social lab @mpi-cbg.de and the rest of the team to this fantastic publication: www.nature.com/articles/s41...
How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? π€
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
Tissue mechanics and synth morphogenesis folks!
Would you or someone in your lab be up for recording a video of a protocol you use? Something hard to explain without seeing it done?
In the limbo hours π between today and 2026π, if something comes to mind -get in touch!
#JoVE organizes the filming π€³
Beads moving around in the lumen of a developing lung, taken my first month of my postdoc when I was playing around with how I could make different viscoelastic material measurments.
Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some π₯ new results in here since the biorvix incl (1) a new RARE-GFP reporter β³οΈπ, (2) additional NMP quantification π’, (3) no neural tube patterning on RA inhibition π etc. Enjoy! π www.nature.com/articles/s41...
For this festive season, Iβm sending friends and family something a little different: postcards straight from the microscope. π¬
Featuring my hiPSC Christmas tree from last year and a hiPSC colony turned into a festive bauble, with wishes for a season thatβs festive at every scale. π
I am putting together a collection of video-protocols we (will) use in tissue mechanics researchπ
I hope to help consolidate established methods, but also showcase a few up-and-coming ones in our blooming field.
Abstract submission by March 2026! Get in touchβ¨
#JoVETissueMech
#ReproducibleTissueMech
Cells can sense the geometry of their environment, from tiny subcellular features to whole-tissue patterns. How can we engineer environments to systematically probe these responses?
π§΅ I'm @lhinderling.bsky.social from @olivierpertz.bsky.social lab, letβs do a short tour on microfabrication!
Meet the Epithelial Mechanics Fan Club @epimechfc.bsky.social
Nimesh Chahare @onenimesa.bsky.social and Julia Eckert @juliaeckert.bsky.social introduce us to the Epithelial Mechanics Fan Club.
Learn how you can get involved with this community: focalplane.biologists.com/2025/12/04/e...
Itβs time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread, @jorgealmagro.bsky.social
Exciting News! π₯³ Our Epithelial Mechanics Fan Club website is now live! π
π epithelialmechanics.github.io
Discover our #EpithelialMechanics threads and get to know our amazing delegates behind them.
Would you like to share your story? Please DM us!
Join the coolest club on the internet!
#EpithelialMechanics
ππ We finally have a website! ππ
Did you miss a thread?
Want to know who our delegates are?
Do you want to join our big club?
Check it out:
epithelialmechanics.github.io
Huge thanks to all thread-contributors and to you for following us!
π£Announcing the 4th edition of the EMBLβIBEC Conference on βEngineering Multicellular Systemsβ, taking place 11β13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now!
events.ibecbarcelona.eu/embl-ibec-co...
1/ π£βοΈ To study mechanics, we need to apply prescribed forces - how can we do that in living tissues? I am @eigenp.bsky.social and in this thread I'll highlight our new approach for applying tension on epithelial tissues in vivo!
Congratulations Isabela π π
Happy to share that my PhD has finally taken the shape of a paper! β¨
Huge thanks to all authors, especially @davidbrueckner.bsky.social & @ehannezo.bsky.social for leading the modeling and @raimonsunyer.bsky.social & @xaviertrepat.bsky.social for their invaluable supervision.
π§΅π
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see π§΅ π