It’s out! 🐟 We compared three regeneration superstars—axolotl, zebrafish, and Polypterus—to ask how animals regrow limbs and fins. We find shared core processes, and other programs fine-tuned by evolution in surprising, lineage-specific ways. tinyurl.com/mpftkn7y
This is a very thoughtful way of working as a group to determine boundaries on AI use within a lab and I completely agree with their conclusions based on my own experience testing LLM tools!
Screenshot of an academic paper titled: Tagging Very Small Fish: Two Effective and Low Impact Methods. Published in the Journal of Experimental Zoology Part A: Ecological and Integrative Physiology
My lab’s study of behavioral development 🐠 has long faced a roadblock: how do you follow an individual’s development if you can’t identify who’s who? How do you identify a juvenile fish the size of a grain of rice? Here, we share two safe, effective tagging methods! doi.org/10.1002/jez.... 🧪 (1/5)
Pleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking.
It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems.
Preprint: www.biorxiv.org/content/10.6...
[1/6]
Hmmm on a test image I generated using Gemini, it even did a pretty good job of simulating gaussian noise.
Very cool work!
absolutely - I save movies with the author name in the file name and throw them in the same folder as the lecture I want to use them in :) helps my poor addled brain haha
Saving for my axon guidance lecture next year! Beautiful!
A bar graph showing the number of NIH New Innovator awards since their creation in 2007.
So how did it go?
NIH made 43 DP2 awards, the lowest number in a decade.
I really wish Director Bhattacharya would spend doing his actual job rather than badmouthing the agency he is charged to lead and spouting platitudes on podcasts and elsewhere.
6/7
Zara was a star, a cherished friend, and an untiring advocate. I wish she had the chance to stay here with us and help create a brighter future, but she already gave us so much in her time here. I'm glad she will be honored in the next cohort of LE fellows ❤️
Live visualization of extracellular matrix dynamics during development and regeneration in zebrafish https://www.biorxiv.org/content/10.1101/2025.11.02.686082v1
I need to get some better frames now that I'm a big kid (supposedly) but finally got my collection of Bob Goldstein prints in my office! There's a Clare Waterman one out of view too!
My post doc would love this! Let me know if you ever record a lecture.
Poster with QR code linking to the position
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
It is time to recognize research software as a valuable scientific contribution in itself, beyond a tool — and to support it
go.nature.com/438X8qS
Seventies Susumu Ohno vibes! Fashion goes in circles.
In my perfect universe there would be a way to indicate "read & understood" without sending an email, but I am finding i may be unique for academia in my preference for not sending gratuitous short emails like "great, thanks!*
bsky.app/profile/drli...
We also demonstrated some preliminary evidence that immune cells in the brain of older fish are more motile and amoeboid than those of younger fish, similar to changes we see in aging mammals. We are excited to further explore these findings in the Haynes lab!
www.biorxiv.org/content/10.1...
Here's a movie from the 3D neuroimaging paper - this is the telencephalon of a 19 month old tg(kdrl:mCherry, mpeg1:eGFP) fish. We use imaris to strip the top layer (the skin and skull) off the projection so we can see just the tissue beneath the skull. This was taken with a Bruker 2P+ multiphoton.
We are so excited to include these new Fellows-to-Faculty Fellows in the Simons Foundation fold!
Want to image the adult zebrafish brain? Here's a nifty design that I made with the help of a talented master's student, Corey Steinhauser.
Supporting files here!
morgridge.org/research/lab...
Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures.
@nachury.bsky.social
www.biorxiv.org/content/10.1...
Maximising imaging volumes of expanded tissues for inverted fluorescence microscopy https://www.biorxiv.org/content/10.1101/2025.09.12.675899v1
Trying to stay hopeful and see joy in these times, and I thought this was lovely.
This is so sad. I'm so sorry fly friends. Solidarity from team fish. 💔
It looks like as a signatory to the UN Florence Agreement, if you 1) buy an item as a nonprofit or educational institution, 2) from a signatory country, 3) can demonstrate it is for research purposes, and/or 4) the item is not made in the US in significant quantities, you can import duty-free!
I got tickets to a sold out OSees show and this is what convinced my now husband to start dating me. So I owe them.
At least you're not going to get the wrath of r/tvtoohigh
The NIH’s 2024 budget of just under $37B generated $95B in economic activity in 2024 alone. 99.4% of new pharmaceuticals approved from 2010-2019 came from NIH-funded research. I’m hard pressed to think of anything that generates as much direct economic benefit as our NIH did before they destroyed it
