Another shipwreck at the bottom of the sea of blood proteomics.
07.03.2026 02:38
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Another shipwreck at the bottom of the sea of blood proteomics.
Go get em Joe!
This is great news, and I hope all vendors continue to support THE vendor neutral option for MS data. Regardless, it was a shame that Skyline went without funding for a year from SCIEX
My dream is that Skyline is funded by all vendors continuously. All of #teammassspec benefits from the arrangement
New preprint! We did a systematic comparison of proteases, digestion conditions, and labeling methods for histone PTM analysis by MS-based proteomics in the Yates lab at @scripps.edu.
TL;DR: you can get great results in ~3 h of sample prep. π§΅
We need to get more mass spec proteomics folks on here and increase the size of our cluster!
#Proteomics #TeamMassSpec
bluesky-map.theo.io
Closeup of a hand reaching down to grip a baseball. (Mike Zarrilli/MLB Photos)
We'll pick it up from here.
Spring Training and the World Baseball Classic are right around the corner!
1. It was not an accident.
2. It was not a staffer.
3. While the president may have dementia his racism is not due to dementia.
4. He isnβt sorry. He means every racist thought he shares.
5. His base agrees with him.
6. He will do it again.
7. No one in power will hold him accountable.
Working late at night alone in the lab as a grad student. Wrenches in both hands and touched a bare heater wire in a high voltage instrument. I was across the room before I knew what happened.
Anti-ICE protesters in Belfast Maine
Anti-ICE protesters in Belfast Maine
Anti-ICE protesters in Belfast Maine
Anti-ICE protesters in Belfast Maine
#BelfastMaine
#IceOut
#Maine
@pinetreeactivism.org
Belfast Maine, Pop. 7500
Thanks for highlighting this diversity of analyzable tau mods. Our technology is wonderful now, but this advance kicks the problem back to us. How do we think about the relationship of diverse modifications to disease? The real challenge is to formulate new questions and testable hypotheses.
Iβm proud to be leading this fight. Thank you to @maddowblog.bsky.social for highlighting this critical issue.
Our latest article is out in Cell !
Together with the Zernicka-Goetz lab, we show that fertilization triggers proteomic asymmetry in mammalian zygotes, giving rise to alpha vs. beta 2-cell blastomeres with distinct developmental potential.
cell.com/cell/fulltex...
Jared comes out when thereβs money for the family business.
An inspirational example of π¬ππ’ππ§ππ’ππ’π ππ«ππππ’π―π’ππ², π¨π«π’π π’π§ππ₯π’ππ² ππ§π π«π’π π¨π«:
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
You can sell anything to suckers. Just as true in science as in any other human endeavor.
Iβve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.π§ͺ
My story in @science.org (and π§΅on why it's important to come):
www.science.org/content/arti...
Maine has voted in a landslide to reject a Republican-supported ballot initiative that would have restricted voting access heading into the critical 2026 midterms
Turn the volume up!
βTell your children who the cowards were.β
The antibodies donβt work! The race to rid labs of molecules that ruin experiments
Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this.
www.nature.com/articles/d41...
Let's see how that government ban on White House demolition photos is going.
www.pbs.org/newshour/pol...
Vanderbilt response to the Trump βcompactβ is too clever by half. Dodging the immoral dominance play and pretending itβs a reasoned conversation. Vandy wishes to play ball as an elite institution on a level with MIT, Penn and UVA. Struck out looking.
I repeat myself: this is a town of 6000 people in Waldo County, Maine
1700 people out for No Kings in rural Rockland, Maine today⦠more than 4% of the population of Knox County.
#NoKings #Maine #MEPolitics
#NoKings rally Rockland Maine
Speculation: There has been a recency bias in citations for a long time, because the newer work should contain more up-to-date knowledge.
This could reverse. People might increasingly refer to work before the 2020s, because it wouldn't have been corrupted by gen AI.
Turns out, boron-based heterocycles are anything but boring! In fact, some of them are pretty magical...1,2-oxaborines, for example, can be used as precursors to 11(!) other ring systems!
Read more in my latest for @cenmag.bsky.social
cen.acs.org/synthesis/sh...
People need to start highlighting that Miller is actually the shadow President and the one calling the shots. When it was Musk who was doing it, it caused a rift between them so big that after he was out, Musk was bashing Trump claiming he is in the Epstein files.
TrueβBUTβsetting aside the shameless jerks in the stands, the American players staged a thrilling comeback on Sunday to almost win it. In other words, there was an inspiring comeback that arose from the debacle. That is inspiration for America beyond golf.
