Nuno Henrique Franco

134. Words That Shape Perception: Animals in Language with Dr. Nuno Franco (S15)

In case you have 38 min to spare.

open.spotify.com/episode/7DGK...

We Need to Talk about Sexes - Addressing the Prevalence of Single-Sex Animal Studies YouTube video by Nuno Henrique Franco

"We need to talk about sexes"

youtu.be/zA12Txd8lDE

What an incredible #FELASA2025 conference packed with scientific energy and innovation! Outstanding variety of presentations—from thought-provoking lectures to creative and data-rich posters—contributing to the advancement of #animalresearch.

@nunohfranco.bsky.social @stefanogaburro.bsky.social

At the Bratislava Training School, @nunohfranco.bsky.social will teach key principles of #experimentaldesign—such as randomization, blinding, sample size, and bias control—to help ensure that #animalresearch is reliable, #reproducible, and aligned with the #3Rs.

@costprogramme.bsky.social #training

Donald Trump is withdrawing medical research dollars from some of our top universities. This is a disaster for medical breakthroughs. He says it is about Anti Semitism, but criticizing Israel’s policy in Gaza is not per se Anti Semitism.

Peter Marks, MD, PhD Director, Center for Biologics Evaluation and Research U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20903 March 28, 2025 Sara Brenner, MD, MPH Acting Commissioner of Food and Drugs U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20903 Dear Dr. Brenner: It is with a heavy heart that I have decided to resign from FDA and retire from federal service as Director of the Center for Biologics Evaluation and Research effective April 5, 2025. I leave behind a staff of professionals who are undoubtedly the most devoted to protecting and promoting the public health of any group of people that I have encountered during my four decades working in the public and private sectors. I have always done my best to advocate for their well-being and I would ask that you do the same during this very difficult time during which their critical importance to the safety and security of our nation may be underappreciated. Over the past years I have been involved in enhancing the safety of our nation's blood supply, in advancing the field of cell and gene therapy, and in responding to public health emergencies. In the last of these, during the COVID-19 pandemic I had the privilege of watching the vision that I conceived for Operation Warp Speed in March 2020 in collaboration with Dr. Robert Kadlec become a reality under the leadership of HHS Secretary Azar and President Trump due to the unwavering commitment of public servants at FDA and elsewhere across the government. At FDA, the tireless efforts of staff across the agency resulted in remarkably expediting the development of vaccines against the virus, meeting the standards for quality, safety, and effectiveness expected by the American public. The vaccines undoubtedly markedly reduced morbidity and mortality from COVID-19 in the United States and elsewhere. Many of these same individuals applied learnings from the pandemic during a flawless response helping…

ongoing multistate measles outbreak that is particularly severe in Texas reminds us of what happens when confidence in well-established science underlying public health and well-being is undermined. Measles, which killed more than 100,000 unvaccinated children last year in Africa and Asia owing to pneumonitis and encephalitis caused by the virus, had been eliminated from our shores. The two-dose measles, mumps, rubella vaccine regimen (MMR) using over the past decades has a remarkably favorable benefit-risk profile. The MMR vaccine is 97% or more effective in preventing measles following the two-dose series, and its safety has been remarkably well studied. Though rarely followed by a single fever-related seizure, or very rarely by allergic reactions or blood clotting disorders, the vaccine very simply does not cause autism, nor is it associated with encephalitis or death. It does, however, protect against a potential devasting consequence of prior measles infection, subacute sclerosing panencephalitis (SSPE), which is an untreatable, relentlessly progressive neurologic disorder leading to death in about 1 in 10,000 individuals infected with measles. Undermining confidence in well-established vaccines that have met the high standards for quality, safety, and effectiveness that have been in place for decades at FDA is irresponsible, detrimental to public health, and a clear danger to our nation's health, safety. and security. In the years following the pandemic, at the Center for Biologics Evaluation and Research we have applied the same unwavering commitment to public health priorities to the development of cell and gene therapies to address both hereditary and acquired rare diseases. During my tenure as Center Director we have approved 22 gene therapies, including the first gene therapy ever to be approved in the United States. However, we know that we must do better to expedite the development of treatments for those individual suffering from any one of the thousan…

Peter Marks’s resignation letter. Everyone should read this.

Age yourself with a cartoon you watched as a kid.

TEATIME members @okalliokoski.bsky.social and @nunohfranco.bsky.social are leading a workshop before #FELASA2025 in Athens, as part of ESLAV/ECLAM summer school.

eclam.eu/home/pre-diploma/residents/suggested-study-references/study-resources/eslav-eclam-summer-school/

#animalresearch

Our member @nunohfranco.bsky.social updated us on the progress of a new paper and an experimental design #workshop he is organizing for TEATIME members in April.

#animalresearch @costprogramme.bsky.social

New paper on Animal Welfare journal!

We explored contactless body temperature assessment as a refinement for signalling humane endpoints in a mouse model of sepsis.

TL:DR: Subcutaneous temperature is a better predictor than weight loss, in severe murine models of sepsis.

doi.org/10.1017/awf....

Happy to share that I will be a guest speaker at the ESLAV/ECLAM Summer School in Athens, delivering a full-day Experimental Design workshop with Otto Kalliokoski on May 31st 2025.
Register to attend until March 10th.

eclam.eu/home/pre-dip...

Não, não é. Eu já deixei de tentar perceber as pessoas.

If the language required is English, why post a job advert in French?

Could someone explain why Spaniards - and only Spaniards - often send emails with queries in Spanish to an international organization, which website (and courses, and content), is all in English?
What would they say if we replied to them in Finnish, Hungarian, or German?

Animal Research #communication webinar will kick off with the amazing @nunohfranco.bsky.social from i3S - Instituto de Investigação e Inovação em Saúde. He’ll dive into the social acceptability of animal research in the past and present. Don’t miss this fascinating talk!

🗣️ Why is communication in animal research essential?

@nunohfranco.bsky.social (@i3suporto.bsky.social) 🧑‍🔬 highlighted the evolution of social acceptability in animal research over time and its relevance today.

His insights inspire us to reflect on the role of public opinion in science. 🌟💡

Já agora fica mais um esclarecimento. Óxido de ferro (ferrugem) não causa tétano, mas antes o tipo de ferida como aquele causado por um prego, que é profunda e muito estreita, pois cria condições de nas quais as bactérias que causam o tétano proliferam.

Tenho duas contas no Twitter. Uma em inglês, outra em tuga. A primeira mais profissional, onde sigo e sou seguido por colegas, outra mais informal, onde escrevo o que me apetecer.
Comecei a ser seguido e identificado em publicações de colegas estrangeiros no Bsky. E agora? Não quero duas contas!!!

Banger

Gisèle Pelicot, person of the year 2024 Our 2024 Person of the Year has changed the rules, reversed the language and given women permission to reject shame

Gisèle Pelicot, person of the year 2024

www.theneweuropean.co.uk/viva-gisele-...

Eu conheci a minha sogra com 21 anos, de traje académico, ar ressacado, a deixar-lhe a filha às 7.00 da manhã em casa quando ela tinha o primeiro dia de trabalho nesse dia. Passados 23 anos, continuo com a mesma (mulher e sogra) e ela ainda trabalha na mesma empresa.

Não faltam casos de homens com duas mulheres, duas casas, duas famílias. E isso implica que pelo menos uma delas não conheça ninguém da família dele, durante anos. Eu passo por familiares da minha mulher (meu também, por afinidade) quase todos os dias. Parece impossível, mas acontece.

TL:DR - Não pode ser um palerma.

1. O termo "estatisticamente significativo" está mal aplicado e sem referências.
2. Há muita iliteracia numa certa esquerda. É vê-los aos magotes a fazerem Reiki e homeopatia.
3. A legitimação - por via da regulação - de práticas pseudocientíficas foi uma iniciativa de um partido de esquerda.

Se for acima de 10 paus é muito

A literacia científica salva vidas. E carteiras.

What a gay thing to say 😀 Now seriously, these guys are absolute morons.

Já o disse no Twitter, mas porque estou feliz apetece-me partilhar aqui também que a partir de Segunda-feira deixo de ser investigador que atrapalha para ser Investigador Auxiliar.😄
Só tenho pena de ter o haters todos bloqueados.

Estrelinha que o guie...

O segundo nome é a ponta da orelha verbal por onde os pais pegam.

É preciso a própria estar interessada. Mas votava nela sem problema.