Belkaid Lab

Model describing how commensal microbes drive the accumulation of Monocytes to the neonatal skin. Depleting these monocytes in the neonatal window leads to an IL-1 dependent aberrant release of IL-17 from cutaneous T cells later in life. This renders mice more susceptible to psoriasiform inflammation in adulthood.

Excited, grateful, and proud to share our latest research published in Immunity. None of this would have been possible without contributions from all our co-authors, across institutions. Shoutout to @scharschmidtlab.bsky.social for her unwavering support over the years! www.cell.com/immunity/ful...

Big news! We’re thrilled to welcome Pr. Sophie Hüe to the team, bringing her clinical and scientific expertise in inflammatory skin diseases. Excited for what’s ahead! 🔬✨

We’re delighted to welcome Adrien Sprumont as a new postdoc in the lab! 🎊 Looking forward to exciting research, collaborations, and discoveries ahead. 🔬

📣 Job opening in our lab! We're looking for a technician with experience in murine models.
More details about the job description here 👇
www.linkedin.com/jobs/view/4353643662/

Psoriasis: Unraveling the Causes of Chronic Itching In psoriasis and other inflammatory skin diseases, chronic itching or pruritus is a particularly distressing symptom for patients which remains difficult to treat today. Scientists at the Institut Pas...

🧠🧬 Psoriasis: Unraveling the Causes of Chronic Itching

@belkaidlab.bsky.social and Institut Pasteur researchers show that an excessive immune response to skin microbes activates the IL‑17A pathway in nerves, leading to chronic itch and nerve regrowth.

👉 www.pasteur.fr/en/home/rese...

Congratulations to our mentor, Pr. Yasmine Belkaid, for receiving the 2026 Collen-Jeantet Prize for Translational Medicine!

We're excited to welcome @marianapdc.bsky.social to the lab as our newest postdoctoral fellow! We're thrilled to have her expertise in the study of dendritic cells and her energy join the team. 😊 Welcome aboard!

Now online @pnas.org, our latest study, led by @eduardansaldo.bsky.social, reveals how dietary signals drive T-bet–expressing Tr1 cells to dominate the small intestinal immune landscape. Check it out! 👇
www.pnas.org/doi/10.1073/...

Excited to share our new paper in @pnas.org , led by @jdllkss.bsky.social in collaboration with @michelenamorado.bsky.social! We show how the immune system’s response to skin microbes can cause nerve overgrowth and chronic itch, via the molecule IL-17A. ow.ly/LfyU50XQ16y

Merry Christmas from the @belkaidlab.bsky.social at @pasteuredu.bsky.social ✨

Busy experiment day in the Belkaid lab today - lots happening!

Congratulations to @belkaidlab.bsky.social alumni, Jérémie @jdllkss.bsky.social, for a brilliant PhD defense! 🎉

Reframing IL-27: a central regulator of CD8+ T cell immunity Interleukin-27 (IL-27), a member of the IL-12 cytokine family, was long viewed primarily as a regulator of CD4+ T cell immunity. Subsequent studies revealed that IL-27 also directly modulates CD8+ T c...

Want to learn all there is to know about IL-27? Read the review written by @valentinavenzin.bsky.social et al.
dlvr.it/TPMYD7

Incredible science was shared at the #TeamPROSPECT scientific retreat this week bringing together experts in epidemiology, oncology, immunology, computational biology & more. A global effort to understand and reverse the rapid rise of early-onset colorectal cancer.
#CancerResearch #ColorectalCancer

We’re thrilled to have Madeline Edwards joining our team from the US to start her postdoctoral journey. Welcome aboard Madeline!

“Women in Skin Science” prize by Almirall & #ESDR to Prof. Yasmine Belkaid

'Women in science' round table at the ESDR 2025

Thrilled to share that my mentor Prof. Yasmine Belkaid received the “Women in Skin Science” prize by Almirall & #ESDR 🌟👏. At the round table, she rightly reminded us: “Life is too short to be boring, take risks.” 💡💪 #WomenInScience #Skin @esdrorg.bsky.social @belkaidlab.bsky.social

Childhood eczema linked to mother’s stress during pregnancy The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part.

The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part

go.nature.com/45Y9aUQ

Our team is growing! We're happy to welcome @valentinavenzin.bsky.social in the team, joining us from Milan (Italy 🇮🇹). Benvenuto ! 🙂

4 research institute march together hand in hand for diversity and inclusion in science © Franck Aubry

© Franck Aubry

© Franck Aubry

🌈 United for diversity in science 🌈
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social

👩‍🔬 Because diverse labs make better science.
#DiversityInScience

Congratulations to our mentor Yasmine Belkaid on becoming a member of the French Academy of Sciences! @belkaidlab.bsky.social

I am beyond excited 🎉 to share my first post on Bluesky 🩵 to tell you that I have been awarded a MSCA @horizoneu.bsky.social Postdoctoral Fellowship in the @belkaidlab.bsky.social ✨ at @pasteur.fr 🔬.

I #StandUpforSciences because
- it drives the discoveries that save countless lives
- investment in innovation secures our children’s future
- collaboration is the only way to face pandemics alone.
- it strengthens our economies.
- only knowledge can we build a healthier, more resilient world.

First lab retreat of the Pasteur Belkaid team.

Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness Mammary intraepithelial lymphocytes enhance mammary gland differentiation during pregnancy, thereby promoting offspring fitness.

Now available online: our recent work showing that the maternal adaptive immune system promotes optimal lactogenesis. @dancrrl.bsky.social
www.cell.com/cell/fulltex...