Aarushi

We need to be shouting about the effects of this on junior researchers from the roofs, writing to our MPs. We are risking a "missing generation" of researchers.

⚠️ We are hiring a Postdoctoral Research Associate ⚠️
🚨 Deadline 9th February 2026 🚨
👍 Please like and share with your network! 👍

#CambridgeUniversity #PostdoctoralResearch #JobOpportunity

For enquiries please contact me at LP429@CAM.AC.UK or use this 🔗 to apply: www.cam.ac.uk/jobs/postdoc...

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

Abstract submissions for #ISSCR2026 are due in just 2 months! Share your latest discoveries and connect with leading researchers and industry innovators from around the world. Submit by 25 February 2026 👉 https://bit.ly/4owAWzF

UCL researchers slow the progression of Huntington’s disease for the first time with a groundbreaking new treatment

We're looking back on just some of the incredible scientific breakthroughs that came out of our Faculty this year.
First up... Researchers at @uclqsion.bsky.social made global headlines by successfully treating Huntington’s disease for the first time.
www.ucl.ac.uk/news/2025/se...

Uncovering early embryonic communications using new stem cell model New stem cell-based embryo model reveals previously unknown communication between early tissues that become the spine and muscles in the central part of the body.

Lab-grown embryo models let researchers study foundational processes of development. A new embryo model has helped researchers at the Crick to study the neural tube and somites in detail and confirm two-way communication between them.

Read the full story ➡️ www.crick.ac.uk/news/2025-12...

Cancer remodelling of neural circuits YouTube video by BrainPrize

How do nervous system tumours reshape neural circuits?
Join the 2nd #BrainPrize2025 webinar with @michellemonje.bsky.social and Frank Winkler moderating a panel of leading researchers.

#neuroscience #webinar

youtu.be/Lj8pYKhGqKM

NDiff227 gastruloids display a developmental delay in comparison to HM-N2B27 gastruloids. (A) Quantitative analysis of the roundness (perimeter2/4π×area⁠) of gastruloids cultured in either HM-N2B27 or NDiff227 showed that HM-N2B27 gastruloids are significantly less ‘Round’ than their NDiff227 counterparts at 96 h [unpaired two-tailed t-test; t(4)=−4.9541, P=0.008]. Each datapoint is the average roundness of an independent replicate experiment containing between ∼40 and 90 individual gastruloids (see Fig. S4B). (B) The frequency of morphologies from the data in A, with examples of gastruloids that would fall in each category (bottom; the left 'Protrusions' image is also shown in Fig. S4). (C) Light-sheet representative images (maximum projection images) highlighting the expression patterns of Cdh1 (magenta) and Cdh2 (cyan) between HM-N2B27 gastruloids at 96 h and NDiff227 gastruloids at 90 h and 96 h. Gastruloids developed in HM-N2B27 have upregulated Cdh2 by 90 h, unlike NDiff227 gastruloids, which show enhanced Cdh2 only at 96 h. Scale bars: 100 μm. (Ci) Qualitative analysis of the average expression pattern of Cdh2 (N-cadherin). The expression patterns were grouped into two categories (phenotypes I and II) and represent the average of three independent replicate experiments, each containing at least seven individual gastruloids per condition. Examples of the two categories are shown below. The leftmost example for ‘Phenotype I’ is shown in the middle row of 90 h HM-N2B27 (Cdh2) in C. For the box and whisker plot, the central line in the box is the median, the lower edge of the box is the first quartile, the upper edge of the box is the third quartile, and the box height is the IQR. The lower and upper whiskers indicate the smallest datapoint within 1.5xIQR below Q1 or above Q3, respectively.

The power of the media: core culture conditions direct gastruloid development

This Research Highlight showcases the work from Tina Balayo, André Dias @dias-andre.bsky.social, David Turner @gastruloids.bsky.social and colleagues:
journals.biologists.com/dev/article/...

Professor Andrew Morris, Academy President, next to a quote that reads: "This five-year agreement with Wellcome is about building a workforce that can turn scientific discoveries into better patient care."

Professor Rachel McKendry, Executive Director of Discovery at Wellcome Trust, next to a quote that reads: "This renewed commitment will provide future leaders in health and biomedical research the opportunities to develop skills through every stage of their careers."

Pleased to announce our new five-year strategic partnership with @wellcometrust.bsky.social ✨

The agreement, worth over £27m, will boost support for biomedical and health researchers across the UK and address key challenges facing the research workforce.

Explore the details: bit.ly/481qgn5

POV: you are a young woman celebrating a recent academic success

🌞You can survive your PhD write-up without becoming a recluse.

Here’s how @becky-pope.bsky.social managed to stay motivated, keep her weekends, and hand in a thesis she’s proud of🎉

www.womeninneuroscienceuk.org/post/how-to-...

#PhD #ThesisWriting #Advice #WomenInSTEM #EarlyCareerResearcher

A headline: Scientists have discovered a 'third state' between life and death

"Postdoc in the job market"

Sex-specific responses of small RNAs and transposable elements to thermal stress in zebrafish germ cells Environmental fluctuations influence heritable phenotypes through complex molecular mechanisms. In zebrafish (Danio rerio), the interplay between temperature variation, transposable element (TE) activ...

🚨 New preprint alert!
Our latest work from @immler.bsky.social lab 🐟🧬

Sex-specific responses of small RNAs and transposable elements to thermal stress in zebrafish germ cells

#TESky #TE #piRNA #miRNA #zebrafish #DanioDigest
🔗 Read here www.biorxiv.org/content/10.1...

A thread 🧵...

🚨 Big news for the neuroscience community!

The Call for Abstracts, Travel Grants and Registrations for #FENS2026 is officially open! 🧠

👉 Register and submit your work today: https://loom.ly/usQR0ao

🎉 Congratulations to Dr Rachel Honeyghan-Williams (@sciwithrach.bsky.social) on receiving the @womeninneurouk.bsky.social award for Neuroscience Communicator of the Year 2025!
We've loved working with Rachel this year. Check out some of the content we've made together below: 👇

How does foxg1 impact pineal gland development? What are the implications for FOXG1 syndrome?

Lewis Hill, masters student, investigates this in #zebrafish. His image shows in-situ HCR + immuno in foxg1,Gal4;UAS,GFP zebrafish at 24hpf revealing foxg1 mRNA/protein with pineal markers aanat2 & exorh.

A circle composed of many oval-shaped dots, mostly coloured blue apart from a few pink ones in the bottom left corner.

This image shows a mass of human stem cells, collectively known as an ‘organoid’.

We stained the neural crest cells of this organoid to better understand diseases related to defects in their development, such as Hirschsprung's disease and Neuroblastoma.

Image credit: @carmenmorenogon.bsky.social

a woman in a yellow wig and white sunglasses ALT: a woman in a yellow wig and white sunglasses

Please share or forward to anyone interested in joining our lab for a postdoc, details can be found via the link below

shorturl.at/GMbW0

Measles vaccination averted more than 60 million deaths between 2000 and 2023.

In 2023, there were an estimated 107 500 measles deaths globally, mostly among unvaccinated or under vaccinated children under the age of 5 years.

www.who.int/news-room/fa...

We're very excited to welcome Dr. @sumrubayin.bsky.social from the @gurdoninstitute.bsky.social onto the next episode of the podcast! 🎉

Her lab studies the mouse #cerebellum to better understand the regulation of #neural stem cell behavior. 🧠

Space-Grown Brain Organoids Help Advance New Neurological Treatment Did you know some viruses don’t cause illness and can instead be used to treat disease?

Ok, that's wild! Space grown human brain organoids! "The team co-cultured mature neurons and astrocytes on the ISS, and within 72 hours, the cells self-assembled into 3D brain organoids—a feat not possible on Earth"
issnationallab.org/press-releas...

Rosalind Franklin and the damage of gender harassment Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t

Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).

⭐ Congratulations to Dishaa Sinha (@ox.ac.uk) — winner of the Research Support award at the #WiNUKAwards2025!

Dishaa led setup of 27 UK research sites for the FAST Brain Health study, managed genetic and actigraphy data collection in the Great Minds cohort and provided community outreach.

"The UK cannot become a science superpower unless it exploits the full range of talent that we have" - @nramnani.bsky.social

We are now welcoming applications to our BNA Scholars Programme.

🔗 Find out more and apply: www.bna.org.uk/policy-advoc...

#BNAScholars #DiversityInSTEM #Mentorship

Spatial dynamics of brain development and neuroinflammation - Nature A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.

Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...

An iPSC-derived heart muscle cell assembling sarcomeres videoed through a spinning disk confocal microscope by Burnette Lab graduate student, Emma Koory. Alpha-actinin-2 is shown. Colors denote Z slices (red-bottom; green-middle; blue-top). Movie length- 40 hours.

Ludwig Oxford welcomes Dr Manav Pathania Ludwig Oxford is delighted to welcome Dr Manav Pathania as an Assistant Member of the Ludwig Institute for Cancer Research, Oxford Branch.

The Pathania lab will be moving to the Ludwig Institute in Oxford in early 2026. We'll be recruiting postdocs and research assistants soon, so keep an eye out for those job ads and reach out if you want to find out more about the science we have planned!

shorturl.at/thpyK

September in preprints - the Node Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints. The preprints this month are hosted on bioRxiv – use these

Want to catch up on all the #DevBio, #StemCell (& related) preprints that came out in September?

Check out our September #preprint list👇
thenode.biologists.com/september-in...

Check out my blog post!

Highlights from the UK Stem Cell Network – Inaugural Meeting @manchester.ac.uk blog post from @aarushivaidya.bsky.social. She enjoyed presenting her poster and learning from the inspirational talks. @grocottlab.bsky.social @lscn.bsky.social #UKSCN2025 #StemCellResearch #iPSC