Simon Ameer-Beg

We are delighted to announce the Strathclyde Optical Microscopy Course 2026 (SOMC26), taking place in Glasgow from 21st July – 30th July 2026!

Please find more details at shorturl.at/xmUiZ and apply at shorturl.at/MxTlI. Deadline 16 January 2026.

Mechanosensitive biochemical imprinting of the talin interaction with DLC1 regulates RhoA activity and cardiomyocyte remodeling Cardiomyocytes’ sensing of extracellular matrix stiffness is imprinted in the talin interactome and regulates their phenotype.

🎉It's finally out! Mechanosensitive biochemical imprinting of the talin interaction with DLC1 regulates RhoA activity and cardiomyocyte remodeling | Science Advances www.science.org/doi/10.1126/... - Amazing work Emilie, Ioannis and all co-authors and collaborators!

Image quality metrics fail to accurately represent biological information in fluorescence microscopy Image processing methods offer the potential to improve the quality of fluorescence microscopy data, allowing for image acquisition at lower, less phototoxic illumination doses. The training and evalu...

Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5)
www.biorxiv.org/content/10.1...

‼️Programme finalised ‼️Check out the Early Career Symposium programme below 👇 🔬 #mmc2025UK

RMS staff stand next to a van packed with items to take to mmc2025

...And we're off! All packed and ready for #mmc2025 in Manchester next week 😀🔬🚛

We'll see you there - and if you haven't booked your ticket yet, there's still time! (Exhibition tickets are *FREE*) 👇

www.mmc-series.org.uk/general-info...

@bioimaginguk.bsky.social @rmsearlycareer.bsky.social

High-performance genetically-encoded green and red fluorescent biosensors for pyruvate Pyruvate is the end-product of glycolysis and a central metabolite involved in many biochemical pathways. However, a lack of high-performance (i.e., Δ F / F > 10) single fluorescent protein (FP)-base...

New tools! GreenPy and ApplePy are fluorescent biosensors for pyruvate with huge responses (20–40x in vitro) and a range of affinities (10s of μM to mM). These should be game changers for imaging of metabolism! Great work by Shosei Imai @sikmys.bsky.social and team 👏. www.biorxiv.org/content/10.1...

1/5
🚨 New bioengineering tech in our latest pre-print!
Say hello to VISIBLE — a real-time, imaging-guided system that can see, print, sample & manipulate live 3D cell cultures like organoids and neurospheres.
A powerful leap toward automation in complex biology 🔬🤖
📄 doi.org/10.1101/2025...

A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”

Choose Science. Choose Europe.

A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September → europa.eu/!fBTMgF

Bright and clear, the air
Crystalline. Points of light
Glimpsed through hawthorn
Branches entangling.
Fallow fields, flints dark
Mirrors in the bright chalk.
Trees of oak bare
Limbs lifting
Sapphire sky.
Roots blending verdant
Blades pierce through
Revealing paired
Bells ephemeral.

Certainly not a new picture but very much the vibe.
“Blue*bells* come in every size
Some are wise and some otherwise
They got pretty blue eyes”
Ripples Genesis 1976

Abstract Submission Abstract submission has now closed. You can now submit a late breaking abstract through Oxford Abstracts.

Missed the mmc conference abstract deadline but eager to present your latest work? Fear not! Late and Breaking abstracts open until Friday 2 May. More information here: www.mmc-series.org.uk/conference/a... @royalmicrosoc.bsky.social

Image of 3T3-L1 cells stained with ActinGreen, imaged with a laser scanning fluorescence microscope

Are you fed up wasting time and photons in laser scanning microscopy? Our latest work, PerfectlyAverage, can help to determine optimal parameters for line and frame averaging while considering photobleaching. More information in our preprint! 🔬 bit.ly/PerfectlyAve...

Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis Endocytosis is crucial for various physiological processes, facilitating the uptake of membrane proteins and extracellular material. Fast endophilin-mediated endocytosis (FEME), driven by endophilin A...

We provide mechanistic insights that NHSL1 promotes FEME carrier formation via both endophilin and Ena/VASP proteins suggesting that NHSL1 supports FEME through endophilin mediated membrane bending and through Ena/VASP mediated actin polymerisation. www.biorxiv.org/content/10.1...

Latest pre-print from Conor Treacy as part of his PhD with us. We made a linked 3 fluorophore construct to demonstrate cascaded FRET interactions with FLIM before exemplifying it on a new protein-protein interaction.
@c-trass.bsky.social

www.biorxiv.org/content/10.1...

Close up of a European Robin, slightly ruffled

Lunch guest Monday. Very keen to have his opinion included in the discussion and satisfied with the central aims and objectives (obviously not in central London)

Joint A*STAR - King’s College London PhD Studentships in Biomedical Science 2025/26 King's College London is seeking outstanding and motivated students to join our university and the Agency for Science, Technology and Research (A*STAR).

@stroudlab.bsky.social and I have a joint PhD position available as part of the A*STAR Research Attachment Programme. You'll have the opportunity to work across two continents in supportive environments on how nuclear envelope biology affects disease and aging. Details: www.kcl.ac.uk/study-legacy...

Congratulations! Great to hear

Calibration of mCherryTYG by FLIM in Salmonella Typhimurium cells expressing mcherryTYG

FLIM Imaging of mCherryTYG Deciphers pH Dynamics and Lifestyles of Salmonella Typhimurium by Linda Kenney and team: doi.org/10.1101/2025...

Showcasing the latest applications of the Mesolens and demonstrating our $0.08 3D printed optical-quality lenses manufactured using low-cost consumer grade printers! #PhotonicsWest @spie.org

Applications for our Quantitative Imaging: From Acquisition to Analysis 2025 course (Mar 24-Apr 8) are due on Jan 31! Come immerse yourself in microscopy and image analysis with me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott! Please RT

🚨🚨Please repost!! 📢📢
Following last year’s success, International workshop Physics of Biological Systems is back in May! Free registration! Submit talk or poster abstract. Join us in Edinburgh
@edinburgh-uni.bsky.social
bit.ly/EdinPBS2025

Promotional image for Virtual Facility Management Training Course 2025. White text giving event name and dates (19 - 21 March). Five, multi-coloured micrographs make up the background.

📣 Registration is now open for our Virtual Facility Management Training Couse 2025! (19 - 21 March)

Great course on how to run a core facility - with plenty of tips and tricks from the experts!

Book now: www.rms.org.uk/rms-event-ca...

@yorkbioimaging.bsky.social @rmsearlycareer.bsky.social

World’s first fully 3D-printed microscope made in under 3 hours The microscope cost less than £50 to build using an open-source design and a common 3D printer

Our fully 3D-printed microscope is featured in @newscientist.bsky.social www.newscientist.com/article/2462...

Quantitative Imaging: From Acquisition to Analysis Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Join me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott for our two week CSHL course on microscopy & image analysis starting March 24, 2025! Applications are due 1/31/25. meetings.cshl.edu/courses.aspx...

Accurate #superresolution Mesolens #microscopy with large FOV for subcellular structures + interactions. 💡⚛️

View the open access research from @unistrathclyde.bsky.social, #OnTheCover of #SPIE_JBO: www.spiedigitallibra...

Check out the RMS Early Career Award, open now for applicants across the disciplines of microscopy, image analysis and cytometry! 🔬🧪✨

Deadline: 14th February 2025