MKado: a toolkit for McDonald-Kreitman tests of natural selection https://www.biorxiv.org/content/10.64898/2026.03.02.709122v1
MKado: a toolkit for McDonald-Kreitman tests of natural selection https://www.biorxiv.org/content/10.64898/2026.03.02.709122v1
I'm super excited to share that this article was published today in Science! www.science.org/doi/10.1126/...
All made possible by the fantastic group of donors, volunteers and scientists at The American Chestnut Foundation (tacf.org), HudsonAlpha Institute for Biotechnology, and our collaborators.
Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!
New paper! From Sam Snodgrass and @genomeofforrest.bsky.social, w/ @druncie.bsky.social, @gcbias.bsky.social, and a collaboration with Andres Moreno and @santiagogmm.bsky.social. Can we quantify the impact of humans on maize dispersal?
Plant yourself in a comfy chair and lend me your ear:
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Our paper on the mysterious Devonian organism Prototaxites has now finally been published! See the paper here (www.science.org/doi/10.1126/...) and our explainer thread below!
Prototaxites reconstruction by Matt Humpage
New preprint is up!
Not going spoil the results for you π€ but we looked at some βbirdβ vs βbeeβ-pollinated Penstemon hybrid zones and came away with some pretty unexpected results!
β¦ Bernie Sanders statement: βDonald Trump has, once again, shown his contempt for the Constitution and the rule of lawβ¦.β
thanks, the post refers to sexual function at the level of the entire plant, within a single day, so it's not incorrect. how this results from the action of individual flowers over consecutive days is described in more detail in the paper
The alleles are ancient (~44 million yrs old!) maintained by disassortative mating. They regulate same behavior in other spp & are found in 10s-100s more wild relatives of avo, tropical trees for which it would be burdensome to even observe this behavior, but we can predict it's there from their DNA
Whether a plant is A/B depends on the alleles it inherits from its parents at 1 transcription factor, a gene that regulates many other genes in flowers. Expression of the alleles is rhythmic with the day/night cycle and the dominant allele has a phase delay corresponding to flowering time difference
In this time-lapse video of the 'Hass' variety, you can see two sets of flowers opening and closing at different times of day. The 1st set is functionally female, the 2nd set is functionally male. B-type varieties show the complementary pattern
Did you know there are 2 types of avocado varieties? A-types switch from female to male, B-types male to female, within a single day. This reciprocal sex alternation promotes cross-pollination and has a simple genetic basis. Read more in this recent preprint from the final chapter of my PhD thesis π₯
In this time-lapse video of the 'Hass' variety (A-type), you can see two sets of flowers open and close at different times of day. The first set is functionally female, the second set is functionally male. B-types show the reversed pattern
pictured above are Eric Focht and Mary Lu Arpaia, two of the co-authors on the new study
Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.
surely karma for misspelling my name in my exit seminar announcement
Iβll never look at avocados in quite the same way: The latest from UC Berkeley Miller Fellow Jeff Groh who sits in my lab and Ben Blackmanβs lab. He works on balancing selection and molecular mechanisms underlying the coevolutionary phenomenon of mating type alternation (PhD with Graham Koop).
Very excited to share the capstone of my postdoc work with @stepheniwright.bsky.social, co-led by Wright lab grad student Cassandre with contributions from many others.
We combined new methods with high-quality Rumex assemblies to dive into the remarkable history of rearrangement in this genus.
𧬠Just out in Bioinformatics Advances: βtskit arg visualizer: Interactive plotting of ancestral recombination graphs.βΒ
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...
With @aconga.bsky.social we wrote a short Dispatch to highlight two awesome companion papers in @currentbiology.bsky.social by @jeffgroh.bsky.social, @gcbias.bsky.social and by Liu et al. on how the control of heterodichogamy is going nuts in the Juglandaceae :
www.cell.com/current-biol...
Hermaphroditic plants also use TIME β°πΏ to avoid selfing.
Two new @currentbiology.bsky.social papers explore the rapid turnover of this trait in the wingnut family.
Both @vincentcastric.bsky.social and I summarized these findings π authors.elsevier.com/a/1m2MA3QW8S...
#Evolution #PlantBiology
Congratulations to @jeffgroh.bsky.social on the publication of his paper on an ancient balanced polymorphisms controlling heterodichogamy in two genera of wingnuts. The paper shows the putative turnover & reversal of dominance of a mating type polymorphism
www.sciencedirect.com/science/arti...
Sharing our new paper, "Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts". Genomics & evolution of a mating type system involving two morphs with alternating sexes in walnut relatives www.cell.com/current-biol...
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Work led by Marius Roesti, "A species interaction kick-starts ecological speciation in allopatry" now published - Varying degrees of divergence associated with presence/absence of a single interacting species predicts strength of prezygotic RI in freshwater stickleback www.pnas.org/doi/10.1073/...
New Article: "Ginger genome reveals the SMPED1 gene causing sex-phase synchrony and outcrossing in a flowering plant" rdcu.be/eJPdX
SMPED1, located in a dichogamy-determining region in Alpinia species, controls the timing of sex-organ synchrony.
Quantitative system drift https://www.biorxiv.org/content/10.1101/2025.09.17.676933v1
Please share broadly: I am looking for a postdoctoral fellow to work on a collaborative project on the temporal population genomics of invasive Capeweed (using contemporary and herbarium genomics), with βͺβͺ@shaky-dingo.bsky.socialβ¬ and colleagues
Excited to share our new preprint for the tskit_arg_visualizer Python package! ARGs can sometimes feel like a black box, so
@yanwong.bsky.social and I have been developing a method to programmatically drawing these graphs.
π arxiv.org/abs/2508.03958
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