Amelia Eisch 🧪🧠👩‍🔬 🐁

Dr. Jeremy Berg speaking in front of a crowd at Pittsburgh Stand Up for Science.

It’s @jeremymberg.bsky.social talking at Pittsburgh Stand Up For Science. #StandUpforScience

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success. Data source: https://report.nih.gov/nihdatabook/report/302

The data is in: the NIH goalposts have shifted.

What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.

Another manifestation of how HHS policies have led to fewer awards and less science.

Grant Witness is hiring! We're seeking a full-time data scientist to join our team building data resources to support journalism, litigation, and activism protecting science, public health, and the rule of law. grant-witness.us/apply.html #rstats

STAND UP FOR SCIENCE ANNOUNCES MRS. FRAZZLED, INFLUENCER AND PUBLIC EDUCATION ADVOCATE AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally) MARCH 7TH, 2026 NATIONWIDE *Stand Up for Science* logo Join the fight at standupforscience.net

Stand Up For Science announces Mrs. Frazzled (@mrs-frazzled.bsky.social) as a speaker at the Virtual National Day of Action rally on Saturday, March 7th!

(tr.ee/virtual-rally)

Visit standupforscience.net/march7 to find local rally!

#standupforscience
#March7Virtual
#science
#rally
#savescience

On the right side of the photo in white text reads: "STAND UP FOR SCIENCE ANNOUNCES DR. AKILAH CADET, HUMAN RIGHTS ACTIVIST AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally) MARCH 7TH, 2026 NATIONWIDE". Below that is the "STAND UP FOR SCIENCE" logo. Below that in white text reads: "Join the fight at standupforscience.net". To the left side of that is a photo of Dr. Akilah Cadet wearing a shirt that says "KEEP BEING AMAZING".

Stand Up for Science announces Dr. Akilah Cadet, Human Rights Activist as a speaker at the VIRTUAL National Day of Action Rally (tr.ee/virtual-rally), on March 7th 2026, Nationwide.

Join the fight at standupforscience.net/march7

#March7
#standupforscience
#science
#savescience
#rally

Undergraduate students from the #Jadavjilab presented today at the @genetics-gsa.bsky.social #Dros26. I am a #proudPI!

A 1944 map by geologist Harold Fisk charts a 40-mile stretch of the Mississippi River from Friars Point to Gunnison, Mississippi. Fisk used aerial photos and maps to estimate the past and then-present channels. Source: https://www.nationalgeographic.com/science/article/mississippi-rivers-hidden-history-uncovered-by-lidar?fbclid=IwY2xjawQYXkdleHRuA2FlbQIxMABicmlkETFCZ2JBT2tWdVlXMmEzNU5Uc3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHsbjW-Yuubr_o_Kfeh0Elzc94geDwfXIZmeNL7NyljEBAOEjH53m2QLSo1NF_aem__4NkCIJ_D8J6mI1e8eMByg

Rivers are living beings.

Wow this visual is so striking… in a bad way🙃

Habit and hard hat: the unconventional practice of Sister Nesta Fitzgerald-Lombard at St Leonards Mayfield, 1954–1994 This article analyses the career of the nun and architect Nesta Fitzgerald-Lombard (1916–2006) to argue for greater recognition of the unconventional career paths of women architects. Among the fir...

🎉 Just published: my article on nun-architect Sister Nesta Fitzgerald-Lombard and the need to expand perceptions of architectural labour to include women who have followed unconventional paths to practice. Open Access in @thejoa.bsky.social doi.org/10.1080/1360...

The Grosshans lab and their collaborators are using DNA-paint to visualize the protein complexes that mediate cell adhesion during embryonic morphogenesis at unprecedented resolution--check it out! 🧪

Join me at the next No Kings Day

March 28 will be the largest nonviolent protest in American history. Find your local No Kings event to stand up for our communities and reject Trump's fear and violence. app.sosha.ai/s/Ja4OZjQB

The wonderful historic city of Marburg

🚨 University Marburg (Germany) is recruiting a W2 Professor of Mol. Pharmacology in the Faculty of Medicine.

Focus areas: Epithelial adaptation in #inflammation, #regeneration, and/or #cancer

stellenangebote.uni-marburg.de/jobposting/0...

#AcademicJobs #Pharmacology #FacultyPosition #cellbio

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Data Visualization A Practical Introduction

Here’s a full draft of the upcoming second edition of my “Data Visualization: A Practical Introduction”: socviz.co

Job opening: Professorship for Molecular Pharmacology at Marburg University, Germany.

We seek a scientifically outstanding researcher in the field of epithelial biology in inflammation, regeneration, and/or cancer.

stellenangebote.uni-marburg.de/jobposting/0...

Scientists discovered a caterpillar that murders insects and stitches their dismembered body parts onto its back as armor

You’re welcome. Happy day! 😆

Congratulations to the 2026 laureates of the Brain Prize!

ERC grantee Patrik Ernfors (Karolinska Institutet) shares the award with David Ginty (Harvard Medical School) for discoveries on how we sense touch and pain.

Read more about the winners: brainprize.org/winners/touc...

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Figure 1.(A) Classical gel electrophoresis experiments showing mono-, di-, tri-, tetra-, and further multinucleosome bands upon chromatin digestion. (B) The nucleosome repeat length (NRL) is defined as the genomic distance between the centres of two neighbouring nucleosomes.

Figure 2.Nucleosome mapping using MNase-seq versus ATAC-seq. (A) In MNase-seq, nucleosomes in both open and tightly packed genomic regions are accessible to digestion. MNase preferentially cleaves DNA between nucleosomes and digests DNA until it encounters a histone octamer, which provides a footprint of nucleosome-protected DNA regions. (B) Bulk MNase-seq results in averaged maps across millions of cells, effectively capturing all possible nucleosome positioning configurations. (C) Single-cell MNase-seq (scMNase-seq) results in a noisier and sparser signal. The resulting footprints still represent nucleosome-protected regions, but not all nucleosomes are represented. (D) In ATAC-seq, open regions can be accessed by the enzyme Tn5 transposase, which can insert primers in regions free from the binding of nucleosomes and transcription factors (TFs). (E) For open chromatin regions, nucleosome maps can be obtained from ATAC-seq similar to MNase-seq. (F) Closed, tightly packed chromatin regions may be less represented in ATAC-seq nucleosome maps.

Figure 5.Molecular mechanisms affecting nucleosome spacing. (A) Linker histones H1 and nonhistone chromatin proteins which compete with H1s and modulate nucleosome spacing through structural and electrostatic mechanisms. (B) Chromatin remodellers actively reposition nucleosomes following context-dependent rules. (C) Cell state-dependent chromatin boundaries formed by CTCF and other structural proteins, as well as associated recruitment of chromatin remodellers which space nucleosomes. (D) Gene activity associated with remodeller action and RNA polymerases transcribing through the nucleosomes, leading to smaller distances between nucleosomes in regulatory regions and gene bodies. (E) DNA sequence repeats of different types.

Figure 6. Examples of NRL changes in biological systems. (A) Cell differentiation leads to NRL changes between different cell types, e.g. mouse dorsal root ganglia neurons (NRL ∼165 bp) versus cortical astrocytes (NRL ∼183 bp) [175]. Schematic cell shapes are adapted from an image created in BioRender (https://BioRender.com/89trj2t). (B) Paired normal versus tumour breast tissues show NRL shortening in cancer (figure adapted from [36] under the CC BY 4.0 licence (https://creativecommons.org/licenses/by/4.0/)). (C) Nucleosome positioning derived from cfDNA of human volunteers shows NRL increase with age (figure reprinted from [79] under the CC BY 4.0 licence (https://creativecommons.org/licenses/by/4.0/)).

Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: academic.oup.com/nar/article/...

A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy!
@milena-bikova.bsky.social @chrsclrksn.bsky.social

A pen and ink drawing of a dragon by Michelangelo

Michelangelo was born on this day in 1475 in Caprese near Florence, Italy. The painter, sculptor, architect and poet is widely considered to be one of the greatest artists of the Italian Renaissance period.

Assistant or Associate Professor (111338-0226) at University of Warwick An academic position as a Assistant or Associate Professor (111338-0226) is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.

📢 We’re hiring!

The University of Warwick is recruiting for a full-time, permanent academic position in Psychology, available at either:

🔹 Assistant Professor
🔹 Associate Professor

📅 Application deadline: 5th April 2026

This is a great way to start your day (if you happen to be starting now) 🧪 🐤

Can a wealthy family change the course of a deadly brain disease? Inspired by the loss of their mother, they have poured millions into studying a key protein behind frontotemporal dementia. But all has not gone according to plan

Fascinating account of trying to find a cure for frontotemporal dementia (FTD): great advances in our understanding of one variant (mutations in GRN resulting in TDP43 proteinopathy) but no success yet with respect to treatment.

www.science.org/content/arti... #medsky

Behold: the first-ever list of news outlets that have banned generative AI in their reporting. As of today, this is literally information that you cannot find on Google.

My goal is to fill the starter pack, so please send over suggestions with supporting evidence!

go.bsky.app/8cn1XfT

Here's another Hall of Fame sign from last year's MARCH 7th National Day of Action in Washington Square Park, New York City. What's your sign going to say this year?
Visit standupforscience.net/march7 to find your local SATURDAY, MARCH 7th NATIONAL DAY OF ACTION RALLY!

The deadline for our young PI symposium was extended! Don't miss out on this opportunity to build your community and share strategies to navigate these uncertain times.

Stand up for Science Stand up for Science

WASHINGTON D.C.
SATURDAY, MARCH 7th
Join us to Save Science, Protect Health, and Defend Democracy!

Visit this link to learn more! : zurl.co/csUWm

#standupforscience
#scince
#March7DC
#rally

As an ant scientist, I… I’m not even sure what to do with this.

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