Gonzalo Aparicio

Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!

This is the most incredible footage of blue whales I’ve ever seen

Switching fields or wanting to become an expert in #zebrafish research?
The @mblscience.bsky.social 2026 Zebrafish Development & Genetics course offers a fantastic opportunity to learn from leaders in the field!

Application deadline: March 2

Please spread the word!

www.mbl.edu/education/ad...

Wild zebrafish swimming among the aquatic plants in North Bengal. Credit to @jutfelt.bsky.social. #ZebrafishZunday 🧪

'Giant Steps' is an absolute rush

Read more in our Beginner's Guide to John Coltrane: www.treblezine.com/best-john-co...

JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px

@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.

journals.biologists.com/jcs/article/...

Juana Molina : DOGA - Treble The Argentine artist's first new album in eight years is some of her most immediate and mesmerizing to date

Juana Molina's excellent 'DOGA' comprises some of her most warped yet immediate material to date

@1000timesjeff.bsky.social reviews

www.treblezine.com/juana-molina...

some nice circular micropatterns by @bgraedel.bsky.social and msc student moritz in @olivierpertz.bsky.social lab! stamp printed with our microfab method.

International Developmental Mechanics Seminar Series Please fill out the following survey if you are interested in the 2025-2026 International Zoom Seminars on Developmental Mechanics.

🎉 The Developmental Mechanics Seminar Series is back!
🗓️ Thurs, Jan 22
🎙️ Opening talks:
🧬Guy Tanentzapf (UBC)
— How cell adhesion molecules wire into the cytoskeleton
🌀Juan Manuel Gomez Elliff (EMBL)
@gomezjm-devmech.bsky.social
— Mapping tissue mechanics with Brillouin microscopy

What's larger, a protein or its templating mRNA ?

> The mRNA is much larger.

⬛ 𝐀 𝐬𝐞𝐧𝐬𝐞 𝐨𝐟 𝐬𝐜𝐚𝐥𝐞 -- 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐢𝐧𝐭𝐮𝐢𝐭𝐢𝐨𝐧 & 𝐜𝐨𝐧𝐬𝐭𝐫𝐚𝐢𝐧𝐭𝐬 -- 𝐢𝐬 𝐚 𝐩𝐨𝐰𝐞𝐫𝐟𝐮𝐥 𝐞𝐧𝐚𝐛𝐥𝐞𝐫 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡.

The figure shows myoglobin protein drawn to scale next to its mRNA template. The coding sequence of an mRNA ...

🧪 Wondering if HFSP Research Grants are the right fit for you?

You might be a good match if your idea is:
🔹 Too bold or risky for traditional funders
🔹 Strongly interdisciplinary
🔹 Best tackled by an international team

🔗zurl.co/6oyBA
#HFSPResearchGrants #sts

Old school cell division data hand drawn by Wacław Mayzel while he looked through his microscope; circa 1884. #CellBiology

#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you.

www.biorxiv.org/content/10.6...

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

What would Santa Waclaw Mayzel give the good little boys and girls of the world?

Festive drawings of a cell dividing into two daughter cells of course!

Read more about Waclaw Mayzel here: link.springer.com/article/10.1...
#CellBiology

Bárbara Miller en el Laboratorio de Biofilms Microbianos del Dpto. de Microbiología del IIBCE

Bárbara Miller

Detalle de containers

Reconocimiento internacional
La técnica en Biotecnología Bárbara Miller recibió el segundo premio del concurso Biosol 2025, otorgado por la Universidad de Copenhague, en la categoría «por fuera de Europa», por una propuesta con impacto ambiental. 🧵

Call for Letters of Intent - HFSP Research Grants 2027

Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences

I was invited by @focalplane.bsky.social to write a short description about it:

focalplane.biologists.com/2025/12/12/a...

🌊 Developmental biologists say gastrulation is the most important moment of your life… and this sea urchin is making sure it looks fabulous for the occasion 💅
🔴 Laminin 🟢 Skeletal cells 🔵 Membranes 📸 Image from David McClay #FluorescenceFriday #DevBio

🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁  doi.org/10.1016/j.yd...

📜We are thrilled to announce that the latest MorphoNet paper is officially published 🎉 ! Discover 5 varied use cases in which MorphoNet helps segment, curate, evaluate & validate complex 3D+t datasets, and much more 🧑‍💻 ! Read at @elife.bsky.social : doi.org/10.7554/eLif...

🚨 New preprint!
We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework.
www.biorxiv.org/content/10.1...

Above: transverse sections of neurulating chick embryos stained for DNA (methyl green) and F-actin (TRITC-phalloidin), without and with the addition of the phorbol ester PMA. Below: computational simulations of pseudostratified epithelia, with different apicobasal/lateral tension ratios. Either PMA treatment in embryos, or lower ratios in simulations, cause epithelial instability evidenced by extensive cell extrusion.

Paper alert! Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes. @sabr-bio.bsky.social article published as pre-proof in @cellsdev.bsky.social! doi.org/10.1016/j.cd...

Complete your profile and join the Network !

This survey is meant for Latin American developmental biologists (investigators, postdocs, students, and technicians) working in Latin America and abroad.

lasdb-development.org/pages/Latin_...

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.

It ships many new features, detailed below, but that are articulated around the following:

quick test with SAM3 - impressed with how well it seems to track long protrusions? prompted for "cell", does not find anything when looking for "fibroblast" or "nucleus"

Felix Zhou's u-Segment3D is out:

www.nature.com/articles/s41...

It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.

It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.

Sir John Gurdon on the occasion of his 80th birthday. Original portrait by Prof. Nadia Rosenthal of The Jackson Laboratories, pencil on Arches paper. Courtesy of the artist.

"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".

A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...

Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...

My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...