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Sven T. Stripp

@stripplab

The Spectroscopy & Biocatalysis Group @ Uni Potsdam | DFG Heisenberg Fellow | Guest-Prof TU Berlin 2023/24 | Born at 338 ppm | Not a Strip Club https://uni-potsdam.de/en/specbiocat | https://scholar.google.com/citations?user=ZtfyzRoAAAAJ&hl=en

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Latest posts by Sven T. Stripp @stripplab

Angel's Egg | Official Trailer [4K]
Angel's Egg | Official Trailer [4K] YouTube video by Umbrella Entertainment

Glorious remaster of a film that confused and frightened me as a child! Can't say it's less confusing today πŸ€—
youtu.be/SqyVGzaQFpQ?...

07.03.2026 16:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As we used to say, FeS4Life!

07.03.2026 12:25 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Video thumbnail

"SHIT"
"FUCK"
"NO"
"FUCK"
"SHIT"
"FUCK"

06.03.2026 11:30 πŸ‘ 5441 πŸ” 1872 πŸ’¬ 53 πŸ“Œ 90

VOR dem Wecker wach ... wie BeyoncΓ© oder Theo Lingen

10.01.2025 03:51 πŸ‘ 70 πŸ” 6 πŸ’¬ 4 πŸ“Œ 0
Black and white photograph of Fugazi.

Black and white photograph of Fugazi.

#Fugazi have shared a collection of previously unreleased recordings that they produced alongside Steve Albini in late 1992, to be released in aid of Letters Charity

Listen here:

buff.ly/xq02NiX

06.03.2026 21:00 πŸ‘ 55 πŸ” 12 πŸ’¬ 1 πŸ“Œ 3

Buletten mein Lieber (aber Frikadellen lasse ich auch gelten)

06.03.2026 18:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
https://maps.app.goo.gl/gckpBKLxtakNT15s5

https://maps.app.goo.gl/gckpBKLxtakNT15s5

At 9 AM I showed up in swimming trunks and a white towel I had stolen from the hotel only to find this

06.03.2026 15:29 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Grafik, die Nutzerzahlen von OpenAI und Anthropic zeigt und einen starken Verlust fΓΌr erstes und scharfen Anstieg fΓΌr zweites Unternehmen ab dem 25.2. zeigt.

Grafik, die Nutzerzahlen von OpenAI und Anthropic zeigt und einen starken Verlust fΓΌr erstes und scharfen Anstieg fΓΌr zweites Unternehmen ab dem 25.2. zeigt.

Danke an so viele Menschen, ein klares Signal fΓΌr mutiges Handeln gesendet zu haben!
PersΓΆnlich denke ich, dass Go European mit Le Chat von Mistral weiter zentral ist. Aber in diesem direkten Showdown zwischen Werten und Gier war das Signal fΓΌr Anthropic & das US Kriegsministerium wichtig.

06.03.2026 09:31 πŸ‘ 178 πŸ” 50 πŸ’¬ 6 πŸ“Œ 2

Hooray for Johannes!

06.03.2026 07:57 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The good thing about being a vib spec person is being able to use isotopes πŸ™‚

The bad thing about being a vib spec person is being forced to use isotopes ☹️

06.03.2026 07:07 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants www.science.org/doi/10.1126/... @science.org

05.03.2026 21:32 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

NIR and MIR πŸ’ͺ🏻

05.03.2026 21:39 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Say hi to the new kids on the block

05.03.2026 21:14 πŸ‘ 5 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Happy to share our new paper on proton transfer in metalloenzymes, out now in @pccp.rsc.org!
Exploiting crystallography, electrochemistry, FTIR spectroscopy, and QM calculations we identified a Zundel ion in the catalytic proton tranfer pathway of [FeFe]-hydrogenase.
doi.org/10.1039/D5CP...

04.03.2026 12:49 πŸ‘ 10 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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For bonus content, please find a picture of the late, great Georg Zundel attached looking like the late, great Robin Williams πŸ₯°

04.03.2026 13:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Protonation/reduction dynamics at the [4Fe–4S] cluster of the hydrogen-forming cofactor in [FeFe]-hydrogenases The [FeFe]-hydrogenases of bacteria and algae are the most efficient hydrogen conversion catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe–4S] cluster linked to a unique dii...

The new data disprove an older model of ours that suggested protonation of the H-cluster's [4Fe-4S] backend.
doi.org/10.1039/C7CP...
(pub. @pccp.rsc.org)
However, they agree with the proposed presence of a protonated water cluster, H2O5+.
doi.org/10.1038/s414...
(pub. @natcomms.nature.com)

04.03.2026 13:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Happy to share our new paper on proton transfer in metalloenzymes, out now in @pccp.rsc.org!
Exploiting crystallography, electrochemistry, FTIR spectroscopy, and QM calculations we identified a Zundel ion in the catalytic proton tranfer pathway of [FeFe]-hydrogenase.
doi.org/10.1039/D5CP...

04.03.2026 12:49 πŸ‘ 10 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
Preview
BahnBet β€” Bet on German Train Delays Predict Deutsche Bahn delays and win. Real-time prediction markets on ICE, IC & EC train delays.

What I thought was a joke is real: you can now bet on German train delays. bahn.bet

04.03.2026 10:29 πŸ‘ 194 πŸ” 74 πŸ’¬ 15 πŸ“Œ 33

I love how they wrote Gram+ ☺️

04.03.2026 10:32 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Maybe this is just me, but whenever someone says Mossbauer I think of the book Mossflower in the Redwall series. I can’t be the only one.

03.03.2026 23:04 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Fortification of FeS Clusters Reshapes Anaerobic CO Dehydrogenase into an Air‐Viable Enzyme Through Multilayered Sealing of O2 Tunnels Fortification of FeS clusters in Ni─Fe CO dehydrogenase (Carboxydothermus hydrogenoformans) reshapes this anaerobic enzyme into an air-viable variant through multilayered O2 tunnel sealing. The engin...

Contrary to recent claims by Kim et al. (doi.org/10.1002/anie...), Dobbek & Fourmond find that the A559W and A559W/V610H variants of CO dehydrogenase are *not* O2 resistant (Preprint).
www.biorxiv.org/content/bior...

03.03.2026 21:40 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Structural insights into metallocluster trafficking in the nitrogenase assembly scaffold NifEN - Nature Catalysis Structural insights into the assembly of the complex nitrogenase cofactor are scarce. Now, cryo-EM and AlphaFold analyses of NifEN, which converts the precursor (L-cluster) to a mature cofactor (M-clu...

So excited to share our cryo-EM study of the nitrogenase cofactor assembly scaffold NifEN expressed in E. coli!
@ribbehulab.bsky.social @ucibiosci.bsky.social @natcatal.nature.com
www.nature.com/articles/s41...

03.03.2026 18:05 πŸ‘ 18 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
I fucking hate proline so fucking much it's the worst amino acid it's so fucking stupid it's incapable of being fucking normal so it forms an ugly ass ring with itself with its own fucking nitrogen cuz it's a loser fucking amino acid I hate it so much I'd rather cut off my right tit than have to ever draw a mechanism with proline ever again

I fucking hate proline so fucking much it's the worst amino acid it's so fucking stupid it's incapable of being fucking normal so it forms an ugly ass ring with itself with its own fucking nitrogen cuz it's a loser fucking amino acid I hate it so much I'd rather cut off my right tit than have to ever draw a mechanism with proline ever again

Remember that everyone you meet is fighting their own battle, sometimes with amino acids

02.03.2026 00:37 πŸ‘ 265 πŸ” 48 πŸ’¬ 16 πŸ“Œ 7

Made it to ZΓΌri with only minor hiccups, now off for a long day of chat & coffee β˜•

03.03.2026 07:24 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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πŸ“š Studienorientierung Chemie: Die GDCh bietet auf
www.chemie-studieren.de Infos zu Fachrichtungen, Hochschulen und Erfahrungsberichte – fΓΌr alle, die Chemie studieren wollen.
β†’ Reinschauen und teilen – fΓΌr alle, die noch suchen.
#Chemie #Studium #GDCh

02.03.2026 09:08 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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See you next November! ❄️

01.03.2026 22:12 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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HydSL hydrogenase of Thiocapsa bogorovii may participate in sulfur respiration
#hydrogenase #sulfur
doi.org/10.1016/j.bb...

01.03.2026 17:39 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Love it that ZΓΌrich and Berlin have a direct train... 9 hours, wish me luck! πŸ€

01.03.2026 10:51 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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This Tuesday I will be at Uni Zürich @uzh-ch.bsky.social talking about hydrogenase ☺️

01.03.2026 09:13 πŸ‘ 8 πŸ” 0 πŸ’¬ 1 πŸ“Œ 1
Discovery of inhibitors of the Pseudomonas aeruginosa NADH:ubiquinone oxidoreductase (NQR) that hinder virulence factors The growing threat of antimicrobial resistance has created an urgent need to identify novel therapeutic targets in bacteria. The NADH:ubiquinone oxidoreductase (NQR) is a potential target in a number of bacteria that transfers electrons from NADH to ubiquinone while pumping ions from the cytoplasm to the periplasm. In most species, this complex pumps sodium ions, whereas in Pseudomonas aeruginosa it pumps protons, thereby functioning as a member of the electron transport chain. Using a strain of PAO1 with the NQR knocked out, we demonstrate that the NQR complex plays a crucial role in the motility and biofilm development virulence factors in P. aeruginosa. We develop and execute a high-throughput inhibitor screen to identify and confirm compounds that inhibit NADH oxidation by this complex. Using single-particle cryogenic electron microscopy (cryoEM), we determine high-resolution structures of the NQR complex, both inhibitor-free and bound to one of the confirmed hits from our screen, demonstrating that it binds to the ubiquinone binding site. These structures provide insight into conformational dynamics controlled by binding at the ubiquinone site, with potential implications for the coupling between electron transfer and proton pumping in this complex. Biofilm development and motility assays with selected compounds from the screen show that they affect these virulence factors similarly to the NQR knockout. ### Competing Interest Statement The authors have declared no competing interest. Cystic Fibrosis Canada, https://ror.org/05b6dcx13 LKSIoV and University of Alberta Faculty of Medicine and Dentistry Startup funding Striving for Pandemic Preparedness Β– The Alberta Research Consortium Canada Research Chairs Canadian Institutes of Health Research, https://ror.org/01gavpb45 LKSIoV Research Support and Innovation Grant

In the first preprint from the lab, @sandaru-ileperuma.bsky.social demonstrates that the P. aeruginosa NQR complex supports virulence factors and identifies inhibitors of this complex. He also uncovered some interesting NQR dynamics controlled at the substrate binding site. tinyurl.com/yush599n

28.02.2026 21:33 πŸ‘ 12 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0