@ccii-kyoto
Conquering cancer by advancing immunotherapy. The CCII is a research center at Kyoto University, led by Nobel Laureate Prof Tasuku Honjo. https://www.ccii.med.kyoto-u.ac.jp/en/
Register for April's CCII Workshop on Advanced Tissue Imaging & Image Analysis, here in Kyoto.
Org. by Hiroshi Ichise & supported by Leica. Invited faculty: Matteo Iannacone (San Raffaele), Johanne Tracey Jacobsen (Oslo), Guolan Lu (Stanford), Yuki Sugiura (CCII) & Andrea Radtke (Leica).
It's free!
Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity”
For more info. 👇
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
Brown was an early mentor to Tasuku Honjo, who's always acknowledged him (including in his Nobel lecture over 4 decades later, on a completely different topic)
When we were creatin a small exhibition here in @ccii-kyoto.bsky.social, Prof Honjo insisted that it include Don Brown (pic is from a panel)
Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity”
For more info. 👇
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
MHC one–two punch knocks out #cancer. Amir Ghorbani and Jonathan Yewdell @niaidnews.bsky.social discuss new study by Zhang, Chamoto and colleagues @ccii-kyoto.bsky.social (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...
#TumorImmunology #Immunotherapy
The Chamoto lab at CCII works on the interplay of metabolism, ageing, and immunity in the host response to tumors.
Find out more about their research here 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com
#Immunology #Immunotherapy #Metabolism
www.nature.com/articles/s41...
The Chamoto lab at CCII works on the interplay of metabolism, ageing, and immunity in the host response to tumors.
Find out more about their research here 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com
#Immunology #Immunotherapy #Metabolism
www.nature.com/articles/s41...
Here at @ccii-kyoto.bsky.social we had a workshop with @victora.bsky.social @danmucida.bsky.social Angelina Bilate (Rockefeller) & Carolina Lucas (Yale) where I asked them to discuss with the students & postdocs failed projects & negative results, including when to walk away from a project.
CCII's Sidonia Fagarasan & Kenji Chamoto recently discussed recent advances in tumor #metabolism & #immunity at the 2nd
@csisingapore.bsky.social – Kyoto University Joint Symposium.
www.ccii.med.kyoto-u.ac.jp/en/2025/11/2...
Senior Editor Zoltan Fehervari @nature.com recently stopped by CCII to discuss scientific publishing, some of its myths & legends, and what makes for a "good" paper.
#ScientificPublishing #Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
'The deal, announced on December 22, is to be signed off officially in 2026, but Japanese researchers and companies can already apply for calls starting in January and join projects on an equal footing with partners in the EU and other associated countries.'
sciencebusiness.net/news/horizon...
Senior Editor Zoltan Fehervari @nature.com recently stopped by CCII to discuss scientific publishing, some of its myths & legends, and what makes for a "good" paper.
#ScientificPublishing #Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
New findings from Zhang, Honjo, Chamoto et al. @ccii-kyoto.bsky.social indicate that a subset of cancer cells expressing CTAs is sufficient to evoke overall antitumor immunity by broadening T cell responses to other neoantigens. rupress.org/jem/article/...
#TumorImmunology
CCII Vice Director Sidonia Fagarasan introducing Michael Dustin (Oxford), who gave a great talk on the immunological synapse.
For a list of upcoming seminars & events at CCII, visit our webpage.
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
What a great meeting, not sure who else I can on this platform other than @marcsdionne.bsky.social & @cbartman.bsky.social
CSI Singapore is excited to be here on BlueSky! 👋 Read up on cancer research breakthroughs, latest happenings, & events on this space. We hope you stay connected with us on our journey to make significant contributions in cancer research 👨🔬
linktr.ee/csi_singapore
csi.nus.edu.sg/csi-singapor...
CCII's Sidonia Fagarasan & Kenji Chamoto recently discussed recent advances in tumor #metabolism & #immunity at the 2nd
@csisingapore.bsky.social – Kyoto University Joint Symposium.
www.ccii.med.kyoto-u.ac.jp/en/2025/11/2...
Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions
Participants emerge from the conference room into the bright sunlight of Naoshima Island in CCII's first international symposium on Cancer, Metabolism, and Immunity.
CCII sponsored this small, intimate meeting where participants freely shared and discussed ideas & data in a beautiful setting.
These 2 landmark papers came out at the start of my PhD. Science and clinic. Literally back to back. It has been an enduring inspiration ever since to be a part of this wonderful experiment called immunology.
Participants emerge from the conference room into the bright sunlight of Naoshima Island in CCII's first international symposium on Cancer, Metabolism, and Immunity.
CCII sponsored this small, intimate meeting where participants freely shared and discussed ideas & data in a beautiful setting.
Prof Tasuku Honjo is now the Director of CCII, our new center in Kyoto University, dedicated to deciphering anti-tumor immunity and discovering the next generation of cancer immunotherapies.
www.ccii.med.kyoto-u.ac.jp/en/
In the same issue, Revy, Fischer and Durandy showed that the same gene, AID, was responsible for a mysterious form of hyper-IgM syndrome that was not linked to mutations in the CD40 pathway, demonstrating that AID also controlled CSR and SHM in humans.
www.cell.com/fulltext/S00...
Muramatsu had previously reported the discovery of the AID gene in a screen. In the 2000 Cell paper, he and his collaborators in the Honjo lab, including Fagarasan demonstrated its function in mice.
www.cell.com/AJHG/fulltex...
In a @cp-cell.bsky.social Benchmarks article, Masamichi Muramatsu, Sidonia Fagarasan et al tell the story of the discovery of AID in the Honjo lab, solving the decades long mystery of the molecular effector of Ig class switch recombination and somatic hypermutation.
#Immunology
Prof Tasuku Honjo is now the Director of CCII, our new center in Kyoto University, dedicated to deciphering anti-tumor immunity and discovering the next generation of cancer immunotherapies.
www.ccii.med.kyoto-u.ac.jp/en/
In the same issue, Revy, Fischer and Durandy showed that the same gene, AID, was responsible for a mysterious form of hyper-IgM syndrome that was not linked to mutations in the CD40 pathway, demonstrating that AID also controlled CSR and SHM in humans.
www.cell.com/fulltext/S00...
Muramatsu had previously reported the discovery of the AID gene in a screen. In the 2000 Cell paper, he and his collaborators in the Honjo lab, including Fagarasan demonstrated its function in mice.
www.cell.com/AJHG/fulltex...