Siddhartha Mitra

Differential phagocytosis induces diverse macrophage activation states in malignant gliomas Background Diffuse midline glioma (DMG) and glioblastoma (GBM) are aggressive brain tumors with limited treatment options. Macrophage phagocytosis is a complex, tightly regulated process governed by c...

Excited to announce our latest manuscript!
burning question: do macrophages feel the same after “eating” a tumor cell as we do after a bean burrito vs. a kale salad? macrophages are reprogrammed by what they ingest.

jitc.bmj.com/content/13/9...

Finally a Mitra/Hankinson lab outing. Fully rebuilt after COVID. Celebrating birthdays and just each other

Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

An absolutely phenomenal paper: Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication
www.nature.com/articles/s41...

This is awesome. Thanks for starting it

Awesome meeting up with former lab member Sharareh Gholamin and Johana Theruvath at #SNO2024

Phenomenal talk by Doug Hanahan on the intersection of cancer neuroscience and Immunology #SNO2024

Hope I'm the first to post this all time classic on this platform

Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Terrific piece summarizing a recent report: Every dollar of NIH research funding doubles in economic returns

www.fiercebiotech.com/research/rep...

Yes!!! He is coming away from the dark ages… we need to bring our institutes here as well