Albert Koulman

"Breastfed infants receiving formula supplementation show altered lipid and gut microbiota profiles at 3 months of age": www.sciencedirect.com/science/arti...

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@mrcepid.bsky.social researchers led by Prof. Albert @koulman.bsky.social used data from the UK’s National Diet & Nutrition Survey to investigate the ethnic differences in thiamine status.

The survey is currently delivered by @natcen.bsky.social & @mrcepid.bsky.social at the @cam.ac.uk

Ethnic differences in thiamine status persist after adjusting for diet; findings from the UK National Diet and Nutrition Survey Thiamine (vitamin B1) status might play a role in cognition and mental health. Recent research suggests that there are ethnic differences in thiamine …

Ethnic differences in thiamine status persist after adjusting for diet; findings from the UK National Diet and Nutrition Survey": www.sciencedirect.com/science/arti...

All dietary assessment tools have limitation and it is therefore important to objectively determine the measurement error of the tool used. Within the National Diet and Nutrition Survey in the UK we do this regularly . See our recent paper with all the details.

Just out: Folate status shows no relationship with vitamin B12 but reiterates the urgency for folate fortification in the UK.
The prevalence of folate deficiency was assessed based on the serum folate concentrations from 47,240 samples from Aug 2023 to Jan 2025.
link.springer.com/article/10.1...

Cambridge Lactation Network Summer Symposium Join us for an enjoyable and informative meeting to learn more about the lactation research done in and around Cambridge!

📝 Registration is free but required to attend.
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...

@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social

6/12 Transcriptional, proteomic and lipidomic analysis of our cell line models showed up-regulation of redox-protective pathways, alongside changes in lipids, including low levels of peroxisomal/ER ether-linked lipids, and high levels of ferroptosis-susceptible membrane PUFAs.

CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition - Nature Communications CREBBP mutations in B-cell acute lymphoblastic leukemia (B-ALL) are linked to poor prognosis and chemoresistance. Here, the authors show that genetic or pharmacological inactivation of CREBBP sensitiz...

Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com‬. 🧵

www.nature.com/articles/s41...

Would be interesting to know how many injections other groups get out of columns in plasma peptidomics / proteomics experiments?

There are some huge studies out there looking at thousands of samples - how long do columns last? Share your experiences!! #proteomics #peptidomics #teammassspec

For everyone in the Cambridge area interested in metabolomics or lipidomics: CaMeL talks, January 23rd. Please register on www.mrl.ims.cam.ac.uk/events/camel...

Not long now to apply to the @ims-mrl.bsky.social at the University of Cambridge for your postgrad studies next year in order to meet the funding deadline #MPhil #PhD #obesity #metabolism #diabetes
👇 👇 👇 👇
www.mrl.ims.cam.ac.uk/study-us/phd
www.mrl.ims.cam.ac.uk/study-us/tau...

doi.org/10.1016/j.jl...

The saturated fatty acid palmitate (C16:0) is one of the most common fatty acids in our food. However, changing palmitate intake has little impact on the circulating levels. We still understand little of the real effect of saturated fat consumption.

Great idea, please add me in.

The validation of an LC-MS/MS method for the quantification of vitamin D metabolites in human milk and their biological variability in Gambian women Vitamin D is required for healthy growth and development, but data on human milk vitamin D content is limited. We describe a liquid chromatography tan…

What are the normal concentrations of vitamin D in breast milk? We can only know when we have a suitable method. Here we present the validation of an LC-MS/MS method.

www.sciencedirect.com/science/arti...