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@wabniklab

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22.01.2025
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Latest posts by @wabniklab

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🆕📰‼️ #PaperCBGP

🔬 New review from CBGP’s @wabniklab.bsky.social group explores how biology, computer science, math & AI are decoding plant patterning

🧬The integrative approach is shaping a new era in plant biology 🌱

📎 More here: shorturl.at/jHEt9

29.01.2026 08:16 👍 5 🔁 2 💬 0 📌 0
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🆕📰‼️ #PaperCBGP

🔬 A study, co-authored by @wabniklab.bsky.social and published in Science, reveals a molecular mechanism blocking inflorescence termination

🧬 A negative feedback loop buffers the floral signal, opening the door to faster-growing & more efficient crops

📎 shorturl.at/rkPwJ

23.01.2026 08:06 👍 6 🔁 4 💬 0 📌 0

Awesome group and fantastic PI! Apply!

23.01.2026 07:02 👍 1 🔁 0 💬 0 📌 0
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📢 We search candidates to apply for the 2026 FPU PhD grants with us. If you are prepared to advance your career in a stimulating and collaborative environment in our group @cbgpmadrid.bsky.social, we look forward to hearing from you.
🔗 For more details, feel free to DM me.

Spread the word!

16.01.2026 20:04 👍 4 🔁 4 💬 1 📌 0
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Moisture-responsive root-branching pathways identified in diverse maize breeding germplasm Plants grow complex root systems to extract unevenly distributed resources from soils. Spatial differences in soil moisture are perceived by root tips, leading to the patterning of new root branches t...

4. These signaling pathways translate environmental water patterns into root architecture with clear field relevance.

🤔 These insights into moisture-responsive root growth could help improve drought resilience in crops. #Maize #PlantScience

📄 Full paper: www.science.org/doi/abs/10.1...

4/4

15.01.2026 14:34 👍 2 🔁 2 💬 0 📌 0
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🆕📰‼️ #PaperCBGP

🧬 New international study co-led by CBGP researcher Jaime Huerta-Cepas presents an updated phylogenomic database

🔬The new release improves ortholog prediction, protein evolution, and functional annotation across all domains of life

📎 More: shorturl.at/hwXfq

12.01.2026 12:20 👍 4 🔁 1 💬 0 📌 0
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🆕📰‼️ #PaperCBGP

🔬 Researchers from CBGP (@stephanpollmann.bsky.social) together with @cnb-csic.bsky.social, uncover a new biochemical link between auxin and ABA

🌱 The study, published in @newphyt.bsky.social, reveals how IAM connects plant growth and stress responses

📎 shorturl.at/KBi3w

13.01.2026 11:12 👍 6 🔁 4 💬 0 📌 1
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From big data to mechanistic insights: decoding plant complexity with models Recent advances in high-throughput sequencing, imaging, and phenotyping have carried plant science into the era of ‘big data.’ Complex, multi-scale da…

Our recent plant scientist guide to AI and mechanistic modelling in plant science. Have a nice read! Hope it helps #plants #models #AI #bigdata @upm.es @cbgpmadrid.bsky.social 👇
www.sciencedirect.com/science/arti...

12.01.2026 13:35 👍 4 🔁 2 💬 0 📌 0

Thx! Happy holidays to you!

21.12.2025 07:50 👍 0 🔁 0 💬 0 📌 0
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Cell wall–derived mechanical signals control cell growth and division during root development Mechanical changes in elongating root cells guide division of neighboring cells, shaping root development.

Latest from our lab in 2025. A wonderful collaboration with Sabrina Sabatini's team at Sapienza University of Rome. How mechanical signals contribute to root growth and zonation @cbgpmadrid.bsky.social @upm.es doi.org/10.1126/scia...

20.12.2025 09:15 👍 14 🔁 9 💬 1 📌 0
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🆕📰‼️ #PaperCBGP

🫚 A new study, published in Science Advances by @wabniklab.bsky.social & Dr. Sabatini's team of University La Sapienza in Rome, reveals how cell wall–derived mechanical signals control root growth

📎 Read more here: shorturl.at/gIc6U

19.12.2025 20:24 👍 5 🔁 1 💬 0 📌 1

Our lab is seeking candidates to apply for a 3-year postdoctoral fellowship in the area of plant synthetic biology funded by the Spanish Research Council. Deadline for applications is 17 Dec. Please, spread the word! contact: k.wabnik@upm.es

18.11.2025 11:11 👍 4 🔁 4 💬 0 📌 0

Wow cool! COngratz Ari!

30.10.2025 21:14 👍 0 🔁 0 💬 1 📌 0
Fig. 4.Model of auxin de-repression. When the auxin concentration in the nucleus is low (A), the effect of ARFas, as well as other non-ARF transcription factors, is limited by Aux/IAA-mediated recruitment of the TPL co-repressor, closing the locus. As auxin levels rise (B), AFBs ubiquitinate Aux/IAAs, thereby allowing all transcription factors to act on the locus. As a result, there is a significant difference in gene expression between baseline and auxin induction. In afb1,2,3,4 mutants (C), Aux/IAAs are not degraded, and therefore the promoter remains closed. In the iaa2mDII degron mutant (D), one of three Aux/IAAs is stabilized, thereby resulting in only partial promoter closure. In arfasept lines, Aux/IAAs are not recruited to the promoter. While gene expression remains diminished without activating ARFs, other non-ARF transcription factors are allowed to provide baseline gene expression. However, there is no auxin-mediated induction.

Fig. 4.Model of auxin de-repression. When the auxin concentration in the nucleus is low (A), the effect of ARFas, as well as other non-ARF transcription factors, is limited by Aux/IAA-mediated recruitment of the TPL co-repressor, closing the locus. As auxin levels rise (B), AFBs ubiquitinate Aux/IAAs, thereby allowing all transcription factors to act on the locus. As a result, there is a significant difference in gene expression between baseline and auxin induction. In afb1,2,3,4 mutants (C), Aux/IAAs are not degraded, and therefore the promoter remains closed. In the iaa2mDII degron mutant (D), one of three Aux/IAAs is stabilized, thereby resulting in only partial promoter closure. In arfasept lines, Aux/IAAs are not recruited to the promoter. While gene expression remains diminished without activating ARFs, other non-ARF transcription factors are allowed to provide baseline gene expression. However, there is no auxin-mediated induction.

🌱📖 RESEARCH 🌱📖

Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪

29.09.2025 10:42 👍 20 🔁 7 💬 1 📌 1
Fig. 1 (shortened, full legend in paper): Auxin responses and auxin-adjacent transcription factors (TFs) control developmental transitions in bryophyte gametophytes. (A) Wild-type (WT) auxin responses (left) cycling between low and high auxin. Under low auxin, A-ARFs are kept in a repressive complex by AUX/IAAs via recruitment of the TOPLESS co-repressor and associated histone deacetylases (HDACs). Under high auxin, auxin mediates the interaction between TIR1/AFB and AUX/IAAs, leading to AUX/IAA ubiquitination and proteolysis. A-ARFs are then free to interact with SWI/SNF ATPases and histone acetylases (HACs), leading to open chromatin states. Positive (TIR1/AFB, A-ARF, SWI/SNF, HAC), negative (AUX/IAA, TPL, HDAC) and auxin-adjacent (TFs) factors are shown. Auxin is represented by an A.

Fig. 1 (shortened, full legend in paper): Auxin responses and auxin-adjacent transcription factors (TFs) control developmental transitions in bryophyte gametophytes. (A) Wild-type (WT) auxin responses (left) cycling between low and high auxin. Under low auxin, A-ARFs are kept in a repressive complex by AUX/IAAs via recruitment of the TOPLESS co-repressor and associated histone deacetylases (HDACs). Under high auxin, auxin mediates the interaction between TIR1/AFB and AUX/IAAs, leading to AUX/IAA ubiquitination and proteolysis. A-ARFs are then free to interact with SWI/SNF ATPases and histone acetylases (HACs), leading to open chromatin states. Positive (TIR1/AFB, A-ARF, SWI/SNF, HAC), negative (AUX/IAA, TPL, HDAC) and auxin-adjacent (TFs) factors are shown. Auxin is represented by an A.

🌱🧬 INSIGHT 🧬🌱

Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.

📝 Insight: doi.org/10.1093/jxb/...

🔬 Research: doi.org/10.1093/jxb/...

#PlantScience 🧪

22.09.2025 13:32 👍 9 🔁 6 💬 0 📌 0
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ERAD machinery controls the conditional turnover of PIN-LIKES in plants Plant ERAD machinery governs the turnover of auxin transporters involved in developmental and stress responses.

Thrilled to share our latest story on the ERAD machinery and how it controls the conditional turnover of PIN-LIKES for acclimative growth

www.science.org/doi/10.1126/...

20.09.2025 11:07 👍 55 🔁 26 💬 2 📌 1
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🌱 #SeminarSeriesCBGP is back! 🎙️

Join us Sept 2025–Jan 2026 for top voices in plant science at CBGP

📍 CBGP Auditorium + Zoom
🕛 12:30 PM
🔗 Speakers & calendar: shorturl.at/Atsyn
📎 Full schedule w/ Zoom links: shorturl.at/yT3e6

Don’t miss it! 👩‍🔬👨‍🔬

19.09.2025 08:50 👍 5 🔁 2 💬 0 📌 1
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Stem cell regulators drive a G1 duration gradient during plant root development - Nature Plants A positional and developmentally regulated cell cycle duration gradient exists in the root meristem whereby the G1 phase is very long close to the stem cell niche. This relies on the interplay of PLET...

Did you know that there is a cell cycle duration gradient in plant root meristem? New story by joining forces between Plant dynamics lab and Crisanto Gutiérrez & Bénédicte Desvoyes lab @cbgpmadrid.bsky.social @cbm-csic-uam.bsky.social #Plants #roots #cellcycle www.nature.com/articles/s41...

18.09.2025 10:10 👍 14 🔁 8 💬 0 📌 1
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#PaperCBGP

🌱🔬 Plant cell walls are more than physical barriers. They are dynamic shields!

A CBGP review published in @jxbotany.bsky.social explores how cell walls shape plant defense against pests, paving the way for more sustainable farming strategies ♻️🌍

📎 More: shorturl.at/GLNYL

10.09.2025 11:39 👍 9 🔁 5 💬 0 📌 0

#ICAR2025

17.06.2025 17:27 👍 0 🔁 0 💬 0 📌 0

Check out our lab posters: P125 and P88 #ICAR25 #PlantScience @cbgpmadrid.bsky.social To learn about New 4D modeling simulators and auxin-dependent root growth!!

17.06.2025 17:26 👍 2 🔁 1 💬 1 📌 0
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Join the PlantDynamics to develop next-gen 4D organ simulators The @PlantDynamics Laboratory  (https://pdlab.es) is seeking a motivated and talented

PlantDynamics is recruiting a programmer to join efforts in developing plant (and other) organ simulators
euraxess.ec.europa.eu/jobs/341946
Contact me directly if you are interested: k.wabniK@upm.es

08.05.2025 15:11 👍 3 🔁 2 💬 0 📌 0
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We have a new Doctor form the #pollmannlab in town 👨🏻‍🎓Congratulations to Adrián to his wonderful PhD defense 🎉 Outstanding job. Also a great shoutout to the panel for the critical assessment of the work. We will surely pick up some of the points.
@cbgpmadrid.bsky.social @etsiaabupm.bsky.social @upm.es

11.04.2025 16:36 👍 7 🔁 3 💬 1 📌 0
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Our editors write:

- Cell polarity: Unequal signalling and biosynthesis in daughter cells rdcu.be/egIl5

07.04.2025 11:50 👍 17 🔁 5 💬 0 📌 0

de nada!

30.03.2025 19:43 👍 1 🔁 0 💬 0 📌 0

Research Briefing by @routierlab.bsky.social and @sysilveira.bsky.social about our recent paper @natureplants.bsky.social

28.03.2025 18:48 👍 5 🔁 1 💬 0 📌 0
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Mechanical interactions between tissue layers underlie plant morphogenesis Nature Plants - Anthers, the male reproductive organs in plants, are a model to explore the establishment of complex three-dimensional shapes. Live imaging, genetics and modelling reveal an active...

Do you want to know how mechanical interaction between tissue layers controls the formation of complex organ shapes in plants? 🔬🌼
🚨Our latest collaborative work with @routierlab.bsky.social is now published @natureplants.bsky.social
Find out more👉 rdcu.be/efad3

26.03.2025 14:22 👍 92 🔁 41 💬 4 📌 6

Fantastic collaboration! and exciting findings! congratz to all involved!

10.03.2025 22:19 👍 2 🔁 0 💬 0 📌 0
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🌱💡 Computational modeling and genetic experiments confirm that this asymmetry optimizes root growth, ensuring robust meristem function. @wabniklab.bsky.social

10.03.2025 14:58 👍 4 🔁 1 💬 2 📌 0