Ilan davis

Human induced climate change is an existential threat to humans living on the planet. It is also making it harder year in year to find good winter climbing conditions in Scotland. Luckily two weeks ago there was a spell of very cold weather - I climbed in Glen Coe: grade IV Raeburn route.

Deep3DSIM: Super-resolution imaging of thick tissue using 3D structured illumination with adaptive optics Deep3DSIM enables super-resolution imaging >130 µm into complex tissues of fixed and live specimens in an upright configuration, allowing sample manipulation, as well as rapid refocusing without th...

elifesciences.org/articles/102...

I am very excited to share with you our publication building Deep3DSIM microscope using adaptive optic. It allows imaging into an intact fly brain >130 microns with high quality 3DSIM as well as remote focusing without moving the objective or specimen.

David Ish-Horowicz obituary Other lives: Pioneer in the application of molecular biology to developmental genetics

Obituary in the Guardian
www.theguardian.com/science/arti...

Obituary in Development
Development (2024) 151, dev204429.
doi: 10.1242/dev.204429

David Ish-Horowicz memorial symposium, Francis Crick Institute, London, 23 June 2025. - YouTube A public symposium organised by friends, scientific colleages and David's wife Ros Diamond to cellebrate David Ish-Horowiccz's, FRS, scientific achievements,...

Dear friends and scientific colleagues,
(especially those of you who knew David Ish-Horowicz).

Feel free to share the attached PDF widely (all the speakers are happy for the talks to be shared).

Many thanks
Best regards
Ilan

www.youtube.com/playlist?lis...

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

*URGENT* please support NIH research and the NIH employees who are standing up for science at the risk of losing their jobs! Sign *TODAY* in support of the Bethesda Declaration. The senate appropriations committee is reviewing the NIH budget Tuesday at 10 am. SHARE widely! 🧪

A typical part of the playbook for a dictator on the rise, coupled with bringing out troops to suppress democratic protests against their xenophobic policies.

Genius. Just as topical now as when made - I think when Thatcher was first elected as prime minister in the uk in 1980 or so.

Still just as topical!

#Drosophila @flybase.bsky.social requires emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!

Focus on Denmark - EMBO communities in EMBC Member States Facts and figures, life scientists in Denmark, EMBO opportunities

Through its programmes and schemes, scientific #publications, #policy and #innovation, EMBO continues to promote excellence in the #LifeSciences at national, European and global level.

This week, we focus on: #Denmark

www.embo.org/the-embo-com...
🧪 #research #opportunities #funding

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

Another way to donate to save flybase from disappearing:

eur03.safelinks.protection.outlook.com?url=https%3A...

‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.

The Trump administration's chaotic changes to diversity-based funding have left trainees in limbo. My colleagues and I at @thetransmitter.bsky.social spoke to ten neuroscience trainees about what the uncertainty means for them, their research and their futures: www.thetransmitter.org/funding/a-gu...

The wold scientific base is in serious crisis. Including Flybase, the heart and soul of the Drosophila community. Read below. If you work on flies or are a fan or want to help. Please consider donation. As termination of Harvard NIH means flybase will stop after the end of July 2025.

DUNE: new detectors race to discover why the Universe exists Researchers in the US and Japan are racing to build new particle detectors that they hope will explain why the Universe exists.

Scientists in a race to discover why the Universe exists. 🔭 🧪 www.bbc.co.uk/news/article...

Walking through the Glasgow botanical guardians I found d countless magical patterns on the leaves

A pilgrimage to Mt Kailas, Tibet 1987. BBC2 14min 50sec YouTube video by Ilan Davis Lab

You maybe interested in this film I made in a very remote part of Tibet while I was doing my PhD in Developmental Biology, shown on BBC2 in 1988.

A pilgrimage to Mount Kailas - the centre of the universe to Tibetan Buddhism.

youtu.be/ls4doaxVBkg

Thanks a lot

We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...

A tour de force review of the connections between between the nervous and immune systems
www.nature.com/articles/s41...

Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development RNA binding protein combinations control neuronal identity through a network of temporal regulators.

Jeff Lee et al paper from my lab is out now
www.science.org/doi/10.1126/...

I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.

I wonder if anyone has built a continuously variable fluorescent light source using delta optical filters and dichroic mirrors with galvo mirrors and/or piezo movers?

deltaopticalthinfilm.com/knowledge/te...

Interesting analysis free of political bias or opinion. However a popularist with disregard of the law and truth backed by oligarch tech billionaires with no morals may “achieve” much more than is easily predicted by rational expert analysis.

Went to Glen Coe to climb dorsal arête on stone coire nan lochen.
(Triangular cliff in photo). But snow conditions were very poor so went walking instead.

Important to support the societies that manage publications at the face of the onslaught from the commercial rivals.

Moa, which are known to have eaten brightly colored fruit, would also have snacked on colorful truffles, such as this purple Gallacea scleroderma. Noah siegel

I am obsessed with these fungi. LOOK AT HOW WEIRD AND WONDERFUL THEY ARE. I imagine that's what moa thought, too... that story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪 🍄

Tonga volcano eruption released more energy than the most powerful nuclear bomb The eruption of the underwater volcano in Tonga that triggered a tsunami earlier this year (January 2022), released more energy than the Tsar Bomba—the most powerful nuclear bomb ever detonated—accord...

Using this method, we determined that the eruption at Hunga Tonga–Hunga Ha‘apai released ~61 Mt, slightly higher in magnitude than the yield of the Tsar Bomba. The paper is open access (link.springer.com/article/10.1...). #PhysOrg wrote a nice article about our work 🧪⚛️[5/n] phys.org/news/2022-08...

Went winter climbing last Sunday in magnificent conditions in the Cairngorms. Arrived a bit late so the popular climbs were in log jam. Had to do a shorter “off piste” sideline to the right to avoid the crowds

View of Central London from Ken Wood, across Hampstead Heath two days before Xmas eve.