Acclimation to thermal variability increases the intensity of activity and alters the activity window in the temperate dung beetle Onthophagus taurus https://www.biorxiv.org/content/10.64898/2026.03.03.708744v1
Females are protected from semaglutide-induced muscle loss in ob/ob mice https://www.biorxiv.org/content/10.64898/2026.03.03.709376v1
Smooth muscle cell estrogen receptor alpha promotes arterial stiffness in the absence of estradiol https://www.biorxiv.org/content/10.64898/2026.03.03.709417v1
Pancreatic α-cells are required for nutrient homeostasis by regulating dynamic β-cell networks in islets https://www.biorxiv.org/content/10.64898/2026.03.02.709124v1
Myosin binding protein-C limits strain induced cross-bridge detachment in response to rapid stretch in cardiac and skeletal muscle https://www.biorxiv.org/content/10.64898/2026.03.02.709089v1
Blood Pressure Regulates Functional Coupling of L-Type Ca2+ Channels: Reimaging the Foundation of Cerebral Blood Flow Control. https://www.biorxiv.org/content/10.64898/2026.03.02.708544v1
Diet- and metabolic state-dependent remodeling of the mouse brain lipidome https://www.biorxiv.org/content/10.64898/2026.02.27.706713v1
Altered metabolic health during pregnancy in mice with lean polycystic ovary syndrome-like traits from high prenatal AMH https://www.biorxiv.org/content/10.64898/2026.02.26.708393v1
Computational modelling of natural cell-to-cell heterogeneity reveals key parameters that control the diversity of human pancreatic islet β-cell excitability in response to glucose https://www.biorxiv.org/content/10.64898/2026.02.27.708039v1
Uromodulin promotes immune zonation and inhibits alternative inflammasome-mediated activation of immune-to-collecting duct inflammatory signaling in early acute kidney injury https://www.biorxiv.org/content/10.64898/2026.02.26.708299v1
TAK1 regulates skeletal muscle mass, hypertrophic signaling, and metabolic homeostasis in male and female mice https://www.biorxiv.org/content/10.64898/2026.02.26.708345v1
Functional differences in electrolyte transport between the mouse proximal and distal trachea https://www.biorxiv.org/content/10.64898/2026.02.26.708204v1
A Translational Model of MASLD-Associated HFpEF Defines Mitochondrial Dysfunction and Cardiac Plasticity During Disease Progression and Regression https://www.biorxiv.org/content/10.64898/2026.02.26.708088v1
The Herbicide Glyphosate Promotes Hypertension via Gut Microbiota-Mediated Mechanisms https://www.biorxiv.org/content/10.64898/2026.02.25.708064v1
Neuronal ketone body utilization couples exercise and time-restricted feeding to cognitive enhancement https://www.biorxiv.org/content/10.64898/2026.02.25.708044v1
Sex- and hepatocyte PPARγ-dependent effects of an obesogenic dietary approach to induce MASH with fibrosis in mice https://www.biorxiv.org/content/10.64898/2026.02.25.707976v1
Brca1 heterozygosity leads to hepatic steatosis in male and female mice despite sexually dimorphic effects on systemic metabolism https://www.biorxiv.org/content/10.64898/2026.02.25.708005v1
A Workflow for Spatial Transcriptomic Analysis from Intra-operative Human Skeletal Muscle Biopsies https://www.biorxiv.org/content/10.64898/2026.02.24.707605v1
Formate reduces ischemic injury in the male heart by increasing protein S-nitrosation https://www.biorxiv.org/content/10.64898/2026.02.24.707768v1
Combination Treatment with Sclerostin and Dkk1 Antibodies Synergizes with Tibial Loading to Stimulate Bone Formation in Aged Mice https://www.biorxiv.org/content/10.64898/2026.02.23.707532v1
Large increases in resistance training volume do not impair skeletal muscle hypertrophy or anabolic-catabolic molecular signalling in trained individuals https://www.biorxiv.org/content/10.64898/2026.02.23.707462v1
Tactile and pain mechanical sensitivity of the human hand https://www.biorxiv.org/content/10.64898/2026.02.23.707479v1
Time in shells: Complex interaction between biological clock and biomineralisation in Mytilus galloprovincialis https://www.biorxiv.org/content/10.64898/2026.02.23.707208v1
Seed size and source reduction during seed filling effect on quality traits of winter and spring rapeseed https://www.biorxiv.org/content/10.64898/2026.02.21.707178v1
A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a diabetic model https://www.biorxiv.org/content/10.64898/2026.02.20.707094v1
Mitochondrial Bioenergetic Uncoupling and Strain-Dependent Adaptations in a High-Fat, High-Salt Model of Metabolic Dysfunction-Associated Kidney Disease https://www.biorxiv.org/content/10.64898/2026.02.20.707069v1
Intracellular Mechanosensation in Intestinal Smooth Muscle: Piezo1 Complexes Amplify Signaling Beyond the Surface https://www.biorxiv.org/content/10.64898/2026.02.19.706403v1
Brain-derived ketone bodies can replace glucose to power neural function https://www.biorxiv.org/content/10.64898/2026.02.19.706813v1
Sex-specific electrophysiology and cholinergic responses underlie differential mechanisms of arrhythmia vulnerability in rabbit atria https://www.biorxiv.org/content/10.64898/2026.02.18.706701v1
Phosphoproteomics of Hypertrophic Cardiomyopathy Patient Myocardium and Novel hiPSC-CM Model Reveal Protein Kinase A as a Modulator of Microtubule Repolymerization https://www.biorxiv.org/content/10.64898/2026.02.18.706710v1
