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Pam Engelberts

@pam-engelberts

Post doc @cmrqut.bsky.social‬ with a love for imaging, baking, and nature Part of BrisJAMS @brisjams.bsky.social and ISME ECSC @isme-microbes.bsky.social

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20.11.2023
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Latest posts by Pam Engelberts @pam-engelberts

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‼️‼️Registration and Abstract submissions for JAMS15 Now Open ‼️‼️

📅 31 July 2026
📍 Translational Research Institute (TRI), Brisbane.
🧪 Call for abstracts: Now Open till 17th May 2026
👉 Registration: Now Open (lnkd.in/gzfEUgyw).
🦜 Early bird registration closes: 30th April 2026.

04.03.2026 07:31 👍 2 🔁 1 💬 0 📌 0
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Coral microbiomes as reservoirs of unknown genomic and biosynthetic diversity - Nature Reconstructing microbial genomes from 820 reef-building corals collected at 99 reefs across 32 islands throughout the Pacific Ocean highlights the importance of conserving coral reefs as vital reservo...

We are thrilled to announce the newest study from our lab (and great collaborators) is out now in @nature.com

We show that #coral #microbes are untapped "biosynthetic reservoirs", full of unique
natural products.

doi.org/10.1038/s415...

25.02.2026 19:37 👍 10 🔁 6 💬 0 📌 1

Teaser for presentation

20.02.2026 08:05 👍 6 🔁 1 💬 0 📌 0
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🚨 Save the Date | JAMS15 Symposium 🚨

🎉For the first time ever, the JAMS Symposium lands in Brisbane!🎉

📅 31 July 2026
📍 Translational Research Institute (TRI), Brisbane.
🧪 Call for abstracts opening soon — start thinking about what you’d love to present!

10.02.2026 01:14 👍 3 🔁 2 💬 1 📌 0
Understanding microbial ecology and evolution with single-cell genomics - Nature Reviews Genetics Engelberts and Tyson discuss the potential and challenges of microbial single-cell genomics, emphasizing the integration of single-cell omics and meta-omics data as a promising opportunity to reveal t...

Understanding microbial ecology and evolution with single-cell genomics www.nature.com/articles/s41... #jcampubs

01.12.2025 14:32 👍 6 🔁 1 💬 0 📌 0
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🚀 Thinking about life beyond academia?
Join BrisJAMS and Australian Society of Microbiology Qld Branch, this November for an inspiring evening of stories, insights, and real-world advice from scientists who’ve successfully built careers outside the academic path!🌟
6 November 2025, 6:00 PM – 8:00 PM

27.10.2025 00:28 👍 3 🔁 3 💬 3 📌 1

Thanks Steve! It was great working with you on the BrisJAMS committee 🙂

15.09.2025 10:11 👍 0 🔁 0 💬 0 📌 0
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We are starting a new series where we introduce our BrisJAMS committee memebers in a fun-microbiology-kinda way 😊 🔬 🦠 🧫 🧪

Starting with none other than our wonderful Director
- Meghann Thai 😎 😁

08.09.2025 01:48 👍 4 🔁 1 💬 1 📌 0
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Looking for a postdoc that combines wet and dry lab experience?

The EMBL-EBI-Sanger postdoctoral fellowships might be the thing for you!

Choose one of our pre-defined topics or propose your own.

www.ebi.ac.uk/research/pos...

@sangerinstitute.bsky.social

#postdoc #sciencecareers
🧬🖥️🔬

04.09.2025 16:24 👍 21 🔁 15 💬 0 📌 0
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We're looking for an awesome computational #postdoc to join our group @PioneerCampus. You'll explore native cells with #cryoET, get long-term funding (5+ years), and live in Munich! For more info, see our new Cell Architecture Lab website:...

13.08.2019 16:07 👍 11 🔁 10 💬 2 📌 1
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📣 New paper alert! Just out in Cell Reports! pubmed.ncbi.nlm.nih.gov/40644298/
Thrilled to share that we have discovered a brand-new anti-phage defense system! Bacteria have evolved various defense strategies (CRISPR etc) to counter phage attacks. We found a new one - fascinating and dramatic
⚔️🦠❄️🔬

02.08.2025 15:01 👍 151 🔁 53 💬 3 📌 5

We (with Clement Coclet, not on Bsky) had the chance to work on a broad "state of viromics" review. We tried to use this to give an overview of how the field changed over the last ~ 15 years, and also what we think are some of the major remaining challenges. Full-text access at -> rdcu.be/excHt

22.07.2025 15:06 👍 84 🔁 41 💬 2 📌 2

Thank you Courtney! GenomeFISH should work on roots as well, as long as you can get the genomes of the microbes of interest for probe generation :)

17.07.2025 23:10 👍 1 🔁 0 💬 0 📌 0
Activity-targeted metaproteomics enhances the ecophysiological characterization of cryptic syntrophic metabolisms Syntrophic microbial consortia can contribute significantly to the activity and function of anoxic ecosystems, yet are often too rare to study their in situ physiologies using traditional molecular me...

Are you interested in microbes that are rare but active? We combined BONCAT with SIP and metaproteomics to improve the recovery of labeled proteins from such microbes. In this case, it illuminated a new anaerobic syntrophic acetate-oxidizing bacterium.

tinyurl.com/a8j29dsr
#microbiomesky #microsky

16.07.2025 15:49 👍 28 🔁 13 💬 1 📌 0
Logo for the Sandpiper website

Logo for the Sandpiper website

Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵

16.07.2025 21:59 👍 131 🔁 71 💬 7 📌 9

In the target population, the GenomeFISH and DAPI signal are positively correlated, resulting in a normalised signal intensity of ~1 when dividing the GenomeFISH signal by the DAPI signal. For closely related strains, this value drops below 1, as the GenomeFISH signal reduces in strength.

(2/2)

08.07.2025 22:58 👍 0 🔁 0 💬 0 📌 0

Thanks Nicholas! We normalise the GenomeFISH signal to the DAPI signal. As genome copy number and image plane orientation can all influence the signal strength in the target population and probes will also bind to closely related strains, normalisation is key.

(1/2)

08.07.2025 22:56 👍 0 🔁 0 💬 1 📌 0

Thanks Steve!

08.07.2025 21:01 👍 0 🔁 0 💬 0 📌 0

No need for design :) GenomeFISH probes are generated from single amplified genomes or isolate genomes by simply fragmenting the entire genome and fluorescently labelling the fragments.

08.07.2025 06:48 👍 1 🔁 0 💬 1 📌 0

Given the high-throughput nature of GenomeFISH, its superior sensitivity, and its phylogenetic resolution, we hope it will become widely used for the visualisation of complex microbial communities.

08.07.2025 02:33 👍 0 🔁 0 💬 0 📌 0
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It also enables GenomeFISH to reach superior signal intensities compared to traditional FISH, allowing it to visualise microbial lineages that are challenging to visualise with traditional FISH, such as members of the Patescibacteria.

08.07.2025 02:32 👍 0 🔁 0 💬 1 📌 0
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As a result, GenomeFISH can distinguish between strains with up to 99% ANI in mock communities and environmental samples.

08.07.2025 02:32 👍 2 🔁 1 💬 1 📌 0

By targeting the entire genome, GenomeFISH overcomes the inherent limitations of traditional FISH, circumventing the need for probe design and optimisation, while increasing sensitivity and specificity.

08.07.2025 02:32 👍 1 🔁 1 💬 2 📌 0
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GenomeFISH probes can be rapidly generated from single cell genomes obtained from environmental and clinical samples, which are amplified, fragmented, fluorescently labelled, and hybridised to visualise the target microorganism in situ.

08.07.2025 02:31 👍 1 🔁 1 💬 1 📌 0

GenomeFISH is an innovative, genome-based FISH approach that couples high-throughput single-cell genomics with whole-genome hybridisation to visualise microbial communities.

08.07.2025 02:31 👍 2 🔁 1 💬 1 📌 0
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GenomeFISH: genome-based fluorescence in situ hybridisation for strain-level visualisation of microbial communities Abstract. Fluorescence in situ hybridisation (FISH) is a powerful tool for visualising the spatial organisation of microbial communities. However, traditio

Very excited to share the first paper out of my Postdoc @CMR:

GenomeFISH: genome-based fluorescence in situ hybridisation for strain-level visualisation of microbial communities.
@sjmcilroy.bsky.social @jamesvolmer.bsky.social @benjwoodcroft.bsky.social

doi.org/10.1093/isme...

🧵1/7

08.07.2025 02:30 👍 63 🔁 27 💬 4 📌 2
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Hello BrisJAMS Community :)

BrisJAMS returns this July with an Antimicrobial Resistance Special featuring three fantastic speakers.

📅 Wednesday, 23 July 2025
🕕 6:00–7:30 PM
📍 The Burrow, West End
🍽 Free food provided!
This free event is open to all in the microbiology community.

07.07.2025 06:39 👍 2 🔁 2 💬 1 📌 1
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ISME travel award application The International Society of Microbial Ecology (ISME) would like to support early career scientists to attend the MBK/CEESME joint conference, Thessaloniki, Greece, 22-24/09/2025. By investing in th...

We are happy to announce that @isme-microbes.bsky.social offers 12 travel awards for early-career scientists who will join the #mbkceesme2025 conference.
forms.gle/ExVETmU6XZYz...

16.05.2025 11:10 👍 5 🔁 4 💬 0 📌 0
Lyrebird (phage profiling) Documentation for SingleM

First code release of "SingleM for dsDNA phage"! Lyrebird scans metagenomic reads for marker genes to give a “phage community profile”. It detects many novel phages, many more than standard contig-centric methods. @benjwoodcroft.bsky.social @emerge-bii.bsky.social wwood.github.io/singlem/Lyrebird

16.05.2025 10:55 👍 12 🔁 8 💬 0 📌 1