Julia Varga 🎗

With all my dislike to Trump, eho I do not think never should have been a president, tell this to Iran, it was a misfired rocket on their side.

We will take a break for February and return on March 9 at 3pm CET. Tune in with Benjamin Maier (@bdmaier.bsky.social), Valeria Bica and Dr Aleksandra Panfilova

Register to attend: tinyurl.com/PMCseminar2

Previous seminars: www.youtube.com/@PMCModularity

Wow, very important!

(PDF) P-hacking with one prompt PDF | This brief note reports a mini-experiment, which tested whether major AI systems (Gemini, Claude, and ChatGPT) readily perform p-hacking when... | Find, read and cite all the research you need o...

"P-Hacking with one prompt" by Shigeto Kawahara.

TL/DR: Ask LLMs to find a significant effect, and they will oblige.

www.researchgate.net/publication/...

For breaking the centrifuge part: why don't centrifuges have lid interlocks or similar mechanisms that make starting them without a lid impossible? If you can do that for a kitchen food processor, I'm sure there are solutions for big, expensive equipment - even without AI...

* we didnt need to work only with that rectangle only, which made life easier.

Yes, for smaller, flexible binders, like peptides that is why we only use the part of PAE matrix when the peptide is aligned. When aligning on the domain, everything is much more confident even with very bad peptide conformation and messes up scores. Interestingly, for actifptm, though,*

I am just looking at an xray structure which look dubious. Two H-bonds between 2 interacting proteins, bad packing, also thanks to crystal contacts, other interfaces exist... According to PISA CC, neither of the interfaces is significant for forming the complex. And wen benchmark methods to these...

Come join is for this seminar on proteins and their interactions! It starts in 45 mins!

After 10 years of bioinformatics, I really want to have a talk with
1) authors publishing computational methods with uninstallable environments and without runnable code for new data(!) in field standard format and
2) editors and reviewers who accept these methods for publications
😠😠😠😠😠😠😠

Come and join us for the next seminar!

Are the Chemistry @nobelprize.bsky.social prizes being awarded to too many #Biologists or now #AIResearchers ?

Biological Laboratory | LEGO® Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...

Our new measure for AF-s got an upgrade! Now also usable in local AF3 installation.

Remember to tune in to our next Seminar on Monday September 8!

Along with this: it's tempting to collect technical skills like pokemon, and there certainly is focus on work with breadth that rewards this. But don't forget about the value of depth. Hard to do good science without deep understanding of what you're doing. That only comes from years of immersion.

Have you heard about the Night Science Podcast, where we talk about the actual creative process of doing science? We explore this with discussions with brilliant scientists & also philosophers and artists, to figure out the tricks of the creative scientific trade.
podcasts.apple.com/us/podcast/n...

I also saw a big surge on my linkedin account - more people seem to use that as well instead of twitter.

Unfortunately it’s clear that the Israeli people can’t topple the government or change its ways. Seems like the attorney general, the last gate keeper, will be fired soon. As long as we’re stuck with this government, the war won’t stop. Only international intervention (=the U.S) might do it.

Scientific bedlam at the world’s weirdest and wildest research conference Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.

🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...

STUDY: Denmark tracked over a million children for 21 years, and found vaccines linked to zero extra cases of autism, asthma, or 48 other conditions.

Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.

I am super excited to announce that I will be starting my lab at the Department of Pharmacology of the University of Zurich in Switzerland next year!

What a cliffhanger 😄

In house? Or a published one?

And you were no invited? Sounds worse than a coup 😅😅😅

AlphaFold developer Google DeepMind to fund CASP as NIH funding falls short Protein structure prediction contest CASP gets temporary funding from Google DeepMind as NIH grant runs out.

NEW from me at STAT:

We've learned that DeepMind is going to fund CASP, the protein structure competition that brought Google DeepMind's #AlphaFold to prominence (and a Nobel Prize), as its NIH funding runs out.

More @statnews.com:
www.statnews.com/2025/07/21/c...

🖥️🩺🧪🧬 #bioML

Variant characterization in the intrinsically disordered human proteome Variant effect prediction remains a key challenge to resolve in precision medicine. Sophisticated computational models that exploit sequence conservation and structure are increasingly successful in t...

Variant characterization in the intrinsically disordered human proteome - here is how we did it using short linear motif prediction, AlphaFold, and experimentation. Check out our preprint: www.biorxiv.org/cgi/content/...