Thrilled to receive the 2026 Melanie OβNeill New Investigator Award in Biological Chemistry. Grateful for the phenomenal students, postdocs, collaborators and mentors who power every discovery in our lab! Onward with more nucleic acid chemistry, gene activation and biosensing!!! #NucleicAcids
14.11.2025 23:46
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Amazing work to all the students - what a great a collaboration!
10.03.2025 19:31
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Fluorogenic oligonucleotide cleavage probes with a branched linker improve RNA detection
Abstract. Fluorescent probe-based quantitative polymerase chain reaction (qPCR) is essential for DNA/RNA quantification widely used in research and clinica
Long story: doi.org/10.1093/nar/.... Shorter story: nucleic acid π§¬π©βπ¬chemistry (a flexible glycerol linker) resulted in modular synthesis of DNA probes with the quencher closer to the fluorophore, allowing ~single molecule detection of viral RNA by qPCR amplification & excellent multiplexing capacity!
10.03.2025 19:31
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Fluorogenic oligonucleotide cleavage probes with a branched linker improve RNA detection
Abstract. Fluorescent probe-based quantitative polymerase chain reaction (qPCR) is essential for DNA/RNA quantification widely used in research and clinica
Excited that Bruk's paper academic.oup.com/nar/article/... is published in 1 of my all-time favourite journals - @narjournal.bsky.social This work is special to me: a collaboration with mentor & amazing colleague Prof. Masad Damha & supportive partner/collaborator, Prof. Nathan Luedtke @mcgill.ca
10.03.2025 19:31
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hello and welcome to the 1M people that have joined Bluesky in the last week!!!
12.11.2024 19:39
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