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MetaMorpheus

@metamorpheus

The number of people using expensive, black-box software for proteomics is bewildering.

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20.09.2023
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Latest posts by MetaMorpheus @metamorpheus

I like the idea of you being able to write prescriptions

06.02.2026 18:35 πŸ‘ 2 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0

no

22.01.2026 21:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

incidentally. no language requirement for the chemistry phd at univ of michigan, which was your original question.

08.01.2026 17:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

@elonMUsk laughs HA HA HAHAHAHAHAHAHAHH.

07.01.2026 21:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Min 4 semesters of German in college for bs in chemistry at purdue in the late 80s. no requirement for a ba degree.

07.01.2026 21:57 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Wanna know what's better than a curved monitor? Two curved monitors, donettes, poptarts and coffee. That's what. Oh and cool new preprints. That too!

06.01.2026 21:49 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Here is a list of proteins that you won't be interested in despite having spent hours in the lab collecting and processing samples not to mention thousands of dollars. See you soon for more of same.

06.01.2026 21:43 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

i'm blushing

11.12.2025 15:57 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I don't mean to poke the moose. But, if we need a certain number of professors, why does it matter if they are young or old. Shouldn't it matter that the professors are good at being professors? I'm receptive to a good argument why young are better than old. But i'm a little suspicious.

25.11.2025 19:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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GitHub - pwilmart/mouse_liver_TMT_reanalysis: Reanalysis of large-scale TMT mouse liver studies (2015 and 2021) from the Gygi Lab. Reanalysis of large-scale TMT mouse liver studies (2015 and 2021) from the Gygi Lab. - pwilmart/mouse_liver_TMT_reanalysis

Are you curious about what steps you need to do to analyze very large multi-plex TMT datasets? This is a reanalysis of some Gygi Lab mouse liver data from 2015 and 2021 with 14.5 million MS2/MS3 scans in total. The big data needed a big discussion (kind of a long read).

github.com/pwilmart/mou...

23.11.2025 18:06 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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21.11.2025 17:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

so.....short answer is follow up any search guess w/ legit targeted proteomics. was my thinking. but i'm just trying to see what true believers would say.

13.10.2025 17:32 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

This is all completely hypothetical. According to Chat-GPT, it is rare to find a bacterial protein in plasma outside of a distinct cause (gut performation). But for the sake of argument it offered up flagellin from e. coli. So, let's say I had a couple peptide Ids from that.

13.10.2025 17:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

metaproteomics?????? skeptical scientist here: but, let's say for argument sake you wanted to confidently identify an adventitious bacterial protein in human plasma, is there a "gold-standard" method? I assume the search result is merely the start point.

13.10.2025 16:57 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I've seen a spike in major ampullate spidroins (MaSp1 and MaSp2) from a "certain lab in pittsburgh".

10.10.2025 18:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13...
Please check out all the project descriptions at the site below:

08.10.2025 12:15 πŸ‘ 14 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1

Not bike mechanic? Aren’t you all about the tour de French fries.

24.09.2025 22:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

No one has stepped up to be our cult leader. I’d follow you anywhere. Interested?

24.09.2025 22:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

So. I want to hear about everyone’s alternate life dream. When you finally get disenfranchised, what would you do if you could do what you want?

24.09.2025 20:12 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

I’m thinking we should all form a colony of off-grid proteomics ex-pats (read: formerly employed) where we can all live out our dreams. We can call it Animal Farm.

24.09.2025 20:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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Well. You know my dream....

24.09.2025 17:36 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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The 25 Highest Paying Jobs in Charleston, SC (Sep 25) The top jobs in Charleston, SC (up to $208,700/yr) include: Psychologist, Nurse Practitioner, and Cyber Security Engineer.

www.ziprecruiter.com/g/Highest-Pa...

24.09.2025 16:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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a blurred image of a person sitting at a desk in front of a monitor ALT: a blurred image of a person sitting at a desk in front of a monitor

you also probably remember ripping of the strips on the sides of the paper that were used to feed it. The times they are a changin.

24.09.2025 16:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

What a missed opportunity!!!!!!! @proteomicsnews.bsky.social

Backyard Proteomics: A Case Study with the Black Widow Spider | Journal of Proteome Research pubs.acs.org/doi/full/10....

17.09.2025 20:02 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Food Chocolate GIF - Food Chocolate Yum - Discover & Share GIFs Click to view the GIF

tenor.com/view/food-ch...

20.08.2025 19:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I don't know anything about the monetary side of this.
1. I do love to see more of my old #TeamMassSpec friends here
2. But, the #TeamMassSpec conversation is a pale shadow of its former self :(

07.08.2025 19:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Referee questioned the adoption/accessibility of lc-ms to the research community. I think that's reasonable. So, realistically, how big of a problem do I need to solve to make my method worth the investment and effort? What is a thoughtful response to this critique?

06.08.2025 14:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0

Maybe you could work there and develop a new biometric test that will make it even harder and take longer to get through security? Honestly, it's getting to the point that it is not worth the effort for me to buy a 100 pounds of canned tuna to save 12cent.

04.08.2025 19:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

IDK. I'm confidant that I am wrong most of the time and I don't attend CS conferences. This may be a widespread problem.

04.08.2025 19:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Improved Detection of Differentially Abundant Proteins through FDR-Control of Peptide-Identity-Propagation pubs.acs.org/doi/10....

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#proteomics #prot-paper

30.07.2025 17:00 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1