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Leo Martins (he/him)

@leomrtns

Computational Biologist. Tenure Track Fellow in Signal Processing for Health at the School of Engineering, University of Liverpool. πŸ‡§πŸ‡·πŸ‡―πŸ‡΅πŸ‡ͺπŸ‡ΈπŸ‡¬πŸ‡§πŸ‡¨πŸ‡­ Phylogenomics and Chemometrics. Prog Rock and Post-Punk. C and Python. @leomrtns@mstdn.science

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18.08.2023
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Latest posts by Leo Martins (he/him) @leomrtns

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New OpenFold3 preview out! (OF3p2)

It closes the gap to AlphaFold3 for most modalities.

Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧡1/9

13.03.2026 15:00 πŸ‘ 167 πŸ” 69 πŸ’¬ 1 πŸ“Œ 2

McSweeney hits the nail on the head again! πŸ˜‚

Just one of many creative ideas proposed to recruit students to History classes: Feed instructor with lowest student evaluations to lions in Roman-style
spectacle that brings history to life! 🦁

09.03.2026 14:30 πŸ‘ 43 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1
Microsoft Forms

Could everyday exposures like water, soil, animals, or outdoor air influence antibiotic-resistant infections?

We are studying this through a One Health approach.

Take our short, anonymous survey (a few minutes, open to everyone):

forms.office.com/e/2MeixcU4Hr

#AMR #OneHealth #MicroSky

11.03.2026 11:57 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Head of Engineering, DiSSCo UK:South Kensington Do you want to be part of an exciting programme enabling critical research into biodiversity and climate change? Come and join us as the new Lead Developer for the DiSSCo UK programme.

Head of Engineering, DiSSCo UK based at @nhm-london.bsky.social "This is a rare opportunity to shape the national digital platform that will underpin the UK’s contribution to DiSSCo and unlock the potential of over 140 million natural science collection items." jobs.nhm.ac.uk/Job/JobDetai...

09.03.2026 20:01 πŸ‘ 6 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Next talk: Darrin Schultz (Stanford University) on "Understanding animal evolution through multi-scale synteny" Monday, March 16, 2026 at 9:00 AM PDT

08.03.2026 12:11 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New post, on whether I could get Claude Code to complete a data task that had taken me AGES a decade ago…

kucharski.substack.com/p/how-much-t...

08.03.2026 08:09 πŸ‘ 128 πŸ” 43 πŸ’¬ 5 πŸ“Œ 6
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Journals and publishers crack down on research from open health data sets PLOS, Frontiers, and others announce policies trying to stem the tide of suspect research

Cracking down on research from open health data sets (www.science.org/content/arti...) is just a new formulation of the gatekeepers complaining about "research parasites" (www.science.org/content/blog...).

Before they, themselves, find a way to capitalise on the parasitism: ai.nejm.org

08.03.2026 10:37 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As concluded in the post, the solution is to be **more** open, not less. Reproducible code, data, must be available. You won't solve it by excluding papers that are based solely on open data (like link mentioned in replies). Not at a great scientific cost.

08.03.2026 09:50 πŸ‘ 5 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

How does Claude estimates this? Does it spit out the code so that we can reproduce it?

07.03.2026 10:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Funding from individual donors: lessons from the Epstein case Universities need to establish and empower compliance teams to ensure adherence to ethical funding policies.

Les gars sur le point de rΓ©inventer le labo CNRS des annΓ©es 1990
"a model of a research lab with a flatter hierarchy, individuals from different disciplines working together and stable long-term financial support that doesn’t rely on quick results or fast publication"
www.nature.com/articles/d41...

06.03.2026 15:16 πŸ‘ 3 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0
Picture of Marjane Satrapi alongside a quote from her. The quote reads:

The world is not divided into countries. The world is not divided between East and West. You are American, I am Iranian, we don't know each other, but we talk together and we understand each other perfectly. The difference between you and your government is much bigger than the difference between you and me. And the difference between me and my government is much bigger than the difference between me and you.

And our governments are very much the same...

- Marjane Satrapi, Iranian-French graphic novelist

Picture of Marjane Satrapi alongside a quote from her. The quote reads: The world is not divided into countries. The world is not divided between East and West. You are American, I am Iranian, we don't know each other, but we talk together and we understand each other perfectly. The difference between you and your government is much bigger than the difference between you and me. And the difference between me and my government is much bigger than the difference between me and you. And our governments are very much the same... - Marjane Satrapi, Iranian-French graphic novelist

Thinking about this quote from Persepolis creator Marjane Satrapi again.

28.02.2026 17:18 πŸ‘ 19244 πŸ” 8220 πŸ’¬ 44 πŸ“Œ 122
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Unraveling the Phylogenetic Signal of Gene Expression from Single-cell RNA-seq Data Abstract. Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of phenotypic heterogeneity. Although the predominant focus of scRNA-seq

Extremely happy to see this work finally published in GPB!
Together with @davidposada.bsky.social and Laura Tomas, we explored how far we can push scRNA-seq data beyond gene expression profiling.

doi.org/10.1093/gpbj...

27.02.2026 21:15 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

your definition of "motivated intruder" has been updated

25.02.2026 19:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I'd also add, they should be willing to do it at 8am, and 8 at night (in Winter).

I don't know what LCC cllrs (especially Labour) are on here, but I'd come with you on a work commute of your choosing, or a School Run in your ward, and have a chat about what we found after.

23.02.2026 16:16 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

A week ago, we had an open conversation amongst senior academics in leadership roles and their use of LLMs (in both their leadership capacities and individually). Small group, not representative, but it already taught me a great deal about the diversity of perspectives (& their consequences). 1/

23.02.2026 07:48 πŸ‘ 122 πŸ” 41 πŸ’¬ 1 πŸ“Œ 11

Maybe a stretch, but does anyone here have contacts at Softstar or other video game companies in Taiwan? I'll be going on sabbatical in 2028 and will live in Taipei for a couple months, so I'm trying to establish the projects I'll work on! I already have Bioinformatics contacts, but not games

08.02.2026 03:46 πŸ‘ 9 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

Study not valid since the N of only one arm group was high.

22.02.2026 14:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It may be even worse. Researchers and data generators don't know what is Open (data), thinking it might include restricted access (see GISAID, or the difference with FAIR "as closed as necessary").
A non-open solution may be to have registration, and most will keep on calling it "open".

22.02.2026 11:00 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

This lawsuit seems appalling to me, honestly. I feel for people whose student experience was lousy due to Covid but that's not the fault of universities. "I wanted in-person study." I'm sure you did. Nobody gets what they want in a global pandemic

21.02.2026 17:42 πŸ‘ 709 πŸ” 138 πŸ’¬ 60 πŸ“Œ 10
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β€˜Don’t go to the US – not with Trump in charge’: the UK tourist with a valid visa detained by ICE for six weeks Karen Newton was in America on the trip of a lifetime when she was shackled, transported and held for weeks on end. With tourism to the US under increasing strain, she says, β€˜If it can happen to me, i...

A retired British primary school administrator with a British passport and a valid visa was shackled, chained and detained for six weeks by ICE

www.theguardian.com/us-news/2026...

21.02.2026 06:54 πŸ‘ 7238 πŸ” 4208 πŸ’¬ 249 πŸ“Œ 631
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Today is the National Day of Remembrance for US Executive Order 9066.

EO9066 illegally confiscated the property and possessions of all Japanese Americans, including my grandparents and other US citizens. It forced them into remote concentration camps for years.

19.02.2026 10:27 πŸ‘ 17 πŸ” 8 πŸ’¬ 2 πŸ“Œ 0

I do think it’s funny that the USA broke from England to get rid of the monarchy so that no one would be above the law and yet only one of these countries has arrested a senior political figure in relation to Epstein and it wasn’t the USA

19.02.2026 13:24 πŸ‘ 624 πŸ” 109 πŸ’¬ 17 πŸ“Œ 4

Just a reminder that faculty with intersectional privilege should be *actively* and *vocally* and *consistently* standing with marginalized colleagues. Just because you're not in the Epstein files doesn't mean you're making academia a better place. Use your privilege. Step into the gap.

13.02.2026 12:42 πŸ‘ 59 πŸ” 16 πŸ’¬ 0 πŸ“Œ 1

is that babyspeak for "toilet"? I see they have toilets specific for babies.

13.02.2026 09:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Roots and Wings | Nasmille Liceth Larke-MejΓ­a A tribute to women and girls in science

On Women and Girls in Science Day, I shared a reflection on strong roots, unexpected paths, and learning to grow into your own wings.

A little science, a little story, and a lot of curiosity.

nasmillelarkemejia.com/roots-and-wi...

#WomenInScience
#InternationalDayOfWomenAndGirlsInScience

12.02.2026 19:15 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
The Conversation

from what I remember, we can be invited by our press officer to write about a recent paper we're experts on, or we can pitch an idea directly to The Conversation theconversation.com/uk/pitches (consultation with the press officer strongly suggested). Someone dropped the ball on this pitch.

12.02.2026 08:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I expect to see more of these promises of future research. Grant funding is getting fierce, their grandiose claims are less scrutinised bsky.app/profile/leom...

And yes, The Conversation should have brakes on this, passing through their editorial team and supported by a university press officer.

12.02.2026 08:52 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Palantir's Swiss Exit Highlights Global Data Sovereignty Challenge | NewsCase Switzerland's military has terminated its contract with Palantir Technologies Inc. following a security audit. The review concluded that U.S. intelligence ag

"Switzerland’s military has terminated its contract with Palantir… following a security audit… concluded that U.S. intelligence agencies could potentially access sensitive Swiss defense data… significant reputational warning for the data analytics firm"

www.newscase.com/palantirs-sw...

#R4Today

11.02.2026 07:05 πŸ‘ 3253 πŸ” 1624 πŸ’¬ 69 πŸ“Œ 312

Nerds assemble! I need recommendations for a speaker who can talk not only about the growth in awareness of ADHD/autism in the UK, and the importance of accommodations etc., but also the sociological aspects of underdiagnosis/stigma in women/minority communities etc.

Pls repost for wider reach, ta.

11.02.2026 12:27 πŸ‘ 59 πŸ” 85 πŸ’¬ 15 πŸ“Œ 5