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PURPOSE: the Pain Research Network

@painresearchers

NIH-funded program uniting #pain #researchers across the continuum of #painresearch, from all disciplines and all career levels. https://bit.ly/m/PURPOSE

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Latest posts by PURPOSE: the Pain Research Network @painresearchers

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How does the brain decide between pain and survival?

Nitsan Goldstein, PhD, and Amadeus Maes, PhD, discuss their work on the PBN’s role in need state analgesia and prioritizing survival over persistent pain.

Watch on PURPOSE: bit.ly/4bm2OlR

#Neuroscience #PainResearch #PURPOSE

04.03.2026 00:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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From β€œCan It Work?” to β€œDoes It Work?”

Explore Priority H with Lynn DeBar & Steven Z. George. The discussion unpacks hybrid trials, integrated care pathways, and bridging clinical efficacy with real world implementation.

Read & join the forum: bit.ly/4cCiliP

#PainResearch

27.02.2026 20:35 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Ep. 12 of the Pain Cohort Series is live.

How does adolescent dysmenorrhea shape chronic pain risk?

Laura Payne, PhD explores sensory processing, brain connectivity, and treatment variability.

Watch: bit.ly/3OsE9TO

#PainResearch #HEAL #WomensHealth

19.02.2026 22:48 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Core principles shape how pain research is designed, conducted, and translated.

In a new HEAL Research Priorities interview, Kathleen Sluka, PhD discusses the core principles guiding HEAL pain research with Stephani Sutherland, PhD.

Read the article and join the discussion:
bit.ly/3MnEZR4

06.02.2026 00:28 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 2
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The next phase of NIH HEAL pain research is coming into focus.

A new article series explores the HEAL Strategic Plan and Pain Research Priorities, offering context and perspective on what comes next for the field.

Read more:
bit.ly/49UFCdY

03.02.2026 20:48 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The Neuroscience Scholars Program application is now open!

Connect with mentors, access professional development resources, and build relationships that will support your research career.

Applications close Wednesday, February 11.

πŸ”— vist.ly/4nntf

#neurosky #neuroskyence #academicchatter

21.01.2026 17:29 πŸ‘ 8 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Pain-sensing neurons in the intestines play an important role in defending the body from threats.

New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.

πŸ”— https://go.nature.com/4jTvO7k

21.01.2026 17:50 πŸ‘ 18 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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Pain and suffering are central to care but often framed too linearly. Sullivan and Williams argue for a circular, unified view aligned with modern neuroscience and essential for integrating biological, psychological, social care. #PAIN bit.ly/3N2uZge

20.01.2026 13:00 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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How can social determinants of health be integrated into pain research and clinical practice?

Join Dr. Laura Wandner for a lecture on Social Determinants of Health and Pain, featuring Emma Karran and Flavia Kapos.

πŸ“… February 17, 2026
πŸ”— Register: bit.ly/49L4DXL

20.01.2026 23:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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How do social and demographic factors influence chronic pain prevalence, experience, and management?

Join Dr. Laura Wandner in conversation with Hanna Grol-Prokopczyk for a Zoom lecture on Sociology and Demography of Chronic Pain.

πŸ“… January 20, 2026 | 3 PM ET / 12 PM PT
πŸ”— Register: bit.ly/493Vr0l

17.12.2025 18:38 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Purpose Meeting Success: K01 Application Funding

Learn how strong Specific Aims, clear audience targeting, and direct Program Officer feedback strengthen competitive K award applications.

πŸ“… March 22–23, 2026
πŸ“ Philadelphia + Online
πŸ”— bit.ly/49puWDF

#PainResearch #PURPOSE #NIH #CareerDevelopment

05.01.2026 19:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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HEAL PURPOSE Conference: Learn, Grow, and Mentor

PURPOSE fosters shared learning among trainees and faculty, focused on mentoring, navigating criticism and failure, and engaging patients as partners.

πŸ“… March 22–23, 2026
πŸ“ Philadelphia + Online
πŸ”— bit.ly/49puWDF

#PainResearch #PURPOSE #HEAL

02.01.2026 19:37 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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PURPOSE Conference 2026
Where pain research creates hope.

Connect early-career and senior pain researchers, support the next generation of pain scientists, and advance safe, effective therapies for chronic pain.

March 22–23, 2026 | Philadelphia + Online
πŸ”— bit.ly/49puWDF

#PainResearch #PURPOSE

30.12.2025 21:02 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The PURPOSE Conference puts a human face on pain research.

People with lived experience of chronic pain are essential partners in improving clinical trials. PURPOSE connects patients, clinicians, and researchers to drive real-world impact.

March 22–23, 2026
Philadelphia + Online
bit.ly/49puWDF

29.12.2025 19:25 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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β€œAs a clinician, getting into research can feel challenging.”

The HEAL PURPOSE Conference helps clinicians connect with researchers and bring research into reality.

πŸ“… March 22–23, 2026
πŸ“ Philadelphia + Online
πŸ”— bit.ly/49puWDF

#PainResearch #HEAL #PURPOSE

26.12.2025 20:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Unlock Your Research Career at the HEAL PURPOSE Conference

In-person, one-on-one feedback from NIH program officers.
Career advice from senior investigators
Real connections with other researchers

That’s the HEAL PURPOSE Conference experience

πŸ“Philadelphia + Online
πŸ”—Register free: bit.ly/49puWDF

24.12.2025 23:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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The 3rd Semi-Annual PURPOSE Meeting takes place March 22–23, 2026, just ahead of the 2026 USASP Annual Meeting.

Free, hybrid meeting focused on interdisciplinary pain research, collaboration, and career development.
Philadelphia + online
Register: bit.ly/49puWDF

#PainResearch #PURPOSE #NIH #HEAL

22.12.2025 20:24 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join Nitsan Goldstein, PhD, and Amadeus Maes, PhD, for a live, interactive lecture on how the brain regulates enduring pain under competing survival demands. This session is discussion focused with a live Q&A. Audience questions welcome.

πŸ“… February 4, 2026 | 11:00 AM PT
πŸ”— Register: bit.ly/3N6NiR9

18.12.2025 18:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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How do social and demographic factors influence chronic pain prevalence, experience, and management?

Join Dr. Laura Wandner in conversation with Hanna Grol-Prokopczyk for a Zoom lecture on Sociology and Demography of Chronic Pain.

πŸ“… January 20, 2026 | 3 PM ET / 12 PM PT
πŸ”— Register: bit.ly/493Vr0l

17.12.2025 18:38 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Advance your career in pain research.
Join Elizabeth Sypek, PhD (NINDS), for an overview of NIH and HEAL career development opportunities.
πŸ“… Jan 7 | 11 AM–12 PM PT
πŸ”— Register: bit.ly/48VvFLn

16.12.2025 22:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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When do patients experience meaningful pain relief?
Episode 14 of the PURPOSE Professional Series explores patient-driven approaches to defining MCIDs in acute pain, including the FDA double stopwatch technique.
Watch the full video: bit.ly/456LhdT

15.12.2025 22:47 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Your NIH Biosketch is more than a formality. It is a strategic tool.
This video walks through how to strengthen your biosketch by clearly communicating your experience, contributions, and impact.
Watch here: bit.ly/4oQGq7E

12.12.2025 23:21 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Huerta et al. find that standard analgesics reliably reduce spontaneous neuropathic pain in preclinical models, mirroring clinical efficacy and highlighting the value of assessing non-evoked pain. Learn more in #PAIN bit.ly/4hHOvJU

25.11.2025 21:00 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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How is AI beginning to reshape pain research? Ep. 9 of the Pain Cohort Series features Anson Kairys, PhD, on how machine learning, deep learning, and large language models are informing pain assessment, treatment-response prediction, and research workflows.
Watch: painresearchers.com/media_center...

24.11.2025 23:26 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain Phosphorylation of hundreds of protein extracellular domains is mediated by two kinase families but the functional role of these kinases is underexplored. We find that the presynaptic release of the t...

Big new paper from us published yesterday: The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain
www.science.org/doi/10.1126/...
Led by @hajisciencebaji.bsky.social in my lab and a wonderful collaboration with Matthew Dalva's lab at Tulane

21.11.2025 18:13 πŸ‘ 52 πŸ” 20 πŸ’¬ 5 πŸ“Œ 1
Preview
Minimum Clinically Important Differences in Acute Pain PURPOSE Web Series: Navigating Careers in Research Wednesday, December 3, 20252:00 PM- 3:00 PM ET / 11:00 AM- 12:00 PM PT Topic:Β  Minimum Clinically Important Differences in Acute Pain Featuring: ...

When is pain relief in a trial clinically meaningful? Join Christopher J. Miller and John T. Farrar as they explain how MCIDs help define real improvement in acute pain.

πŸ“… Dec 3, 2025
πŸ•š 11 AM PT / 2 PM ET
πŸ’» Online

Register: painresearchers.com/events/151186

20.11.2025 23:12 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0