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Tatiana Sandoval Guzmán

@tatianasg

A regeneration biologist… Working at TUD Dresden Fascinated by axolotls and everything that regenerates

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Latest posts by Tatiana Sandoval Guzmán @tatianasg

PoL – Physics of Life | Team | PoL Groups | Benjamin Friedrich Physics of Life: Discover new paradigms for understanding life and deepen our knowledge of living biological matter

Looking for a theory partner for an #HFSP project? #morphogenesis in cells and tissues, #chemotaxis, #cilia? Feel free to reach out! Deadline for letters of intent 26.03.2026.
physics-of-life.tu-dresden.de/team/pol-gro...

03.03.2026 07:17 👍 2 🔁 2 💬 0 📌 0

An amazing work of Sean Keely and a great collaboration network between Germany, Colombia and Japan. @cmcb-tud.bsky.social

26.02.2026 09:46 👍 0 🔁 0 💬 0 📌 0

Kazald1, associated with skeletogenesis and odontogenesis ancestral to jawed vertebrates. Kazald3, commonly lost but it evolved novel expression patterns in teleost fish!
Kazald4, of unknown role, but highly expressed in avian brain.

26.02.2026 09:44 👍 0 🔁 0 💬 1 📌 0
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Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds Natural sciences; Evolutionary biology; Evolutionary developmental biology; Evolutionary history

Just published from our group!
Study of a family of genes, one of them previously associated to regeneration in axolotls (Kazald2) and now we associate its expression during regeneration ancestral of bony vertebrates.

www.cell.com/iscience/ful...

26.02.2026 09:39 👍 17 🔁 2 💬 1 📌 0
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European Amphibian Conference 2026, July 3-5, 2026, Prague, Czech Republic www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

19.02.2026 15:24 👍 9 🔁 5 💬 0 📌 2

We deleted a rhomboid protease… and regeneration went into overdrive.

New preprint from the Neal Lab!
Rhbdl2 restrains macrophage-driven regeneration in zebrafish. 🐟🔥 #Regeneration #InnateImmunity
www.biorxiv.org/content/10.6...

17.02.2026 01:59 👍 35 🔁 9 💬 2 📌 1
European Amphibian Conference 2026 - Sciencesconf.org Friday, July 3, 2026

amphib-conf2026.sciencesconf.org/program?lang...

13.02.2026 09:50 👍 1 🔁 0 💬 0 📌 0

Paper accepted today!! How is that for a Christmas present 🎁

25.12.2025 16:27 👍 10 🔁 0 💬 0 📌 0
Left image source: https://nsarchive.gwu.edu/briefing-book/foia/2019-04-18/redactions-declassified-file. Shows a fully page of redaction, but some headers and individual words are still visible. Also, a page header showing the classification is visible.

Left image source: https://nsarchive.gwu.edu/briefing-book/foia/2019-04-18/redactions-declassified-file. Shows a fully page of redaction, but some headers and individual words are still visible. Also, a page header showing the classification is visible.

Former NSA employee (16 years) with a pro tip for you. Released controlled document on the left, Epstein on the right. See the difference?

In real redactions, some words, headers, and bits will almost always still be visible, but especially classification headers. These documents are UNCLASSIFIED

20.12.2025 15:15 👍 868 🔁 333 💬 16 📌 83
Fig. 1. Doble immunodetection of CD68 and F4/80 during ear hole regeneration in early postnatal mice.

Fig. 1. Doble immunodetection of CD68 and F4/80 during ear hole regeneration in early postnatal mice.

Fig. 6. Clodronate liposomes treated ears in re-differentiation show acceleration of cartilage maturation.

Fig. 6. Clodronate liposomes treated ears in re-differentiation show acceleration of cartilage maturation.

Fig. 4. Modifications in the regenerative response by the treatment with clodronate liposomes during wound healing phase of early postnatal mice ear hole regeneration.

Fig. 4. Modifications in the regenerative response by the treatment with clodronate liposomes during wound healing phase of early postnatal mice ear hole regeneration.

Tissue-resident macrophages are doing more than just protecting from infection. In this interesting paper, René Fernando Abarca-Buis et al shows that they can promote reepithelialization and blastema formation and regulate the maturation of chondrocytes. Check it out here:
doi.org/10.1016/j.cd...

28.11.2025 17:57 👍 8 🔁 5 💬 0 📌 0

I am proud, happy and consider myself lucky to have amazing collaborations, @poldresden.bsky.social @crtd-tud.bsky.social Medical Faculty @tudresden.bsky.social

18.12.2025 14:11 👍 1 🔁 0 💬 0 📌 0

This analysis revealed similarities but also striking differences to what we know in animal models (axolotl for example). It remains a mystery, why more proximal injuries do not regenerate. But studies like this help us understand more closely how we humans can re-form missing structures.

18.12.2025 14:11 👍 0 🔁 0 💬 1 📌 0
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A bit late but a paper from our lab has been published!
Human fingertip regeneration is a fact, it happens in children and adults (not only in children as it has been long believed). We describe here the regenerative phases and analyse the proteome of wound exudates.

www.nature.com/articles/s41...

18.12.2025 14:11 👍 22 🔁 12 💬 1 📌 0
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Could axolotls hold the key to restoring human vision? Axolotls can regenerate optic nerves, retinas, and parts of their brain. Provost's Undergraduate Research Award-winner Ted Chor wants to understand how.

Recent Hopkins Hub article highlighting our work on optic nerve regeneration in axolotl. Congratulations to Ted!
hub.jhu.edu/2025/12/11/s...

12.12.2025 13:53 👍 9 🔁 3 💬 0 📌 0
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LimbNET, an open platform to visualise limb development - El·lipse A new open access platform for the limb development community will close the gap between experiments and mathematical models.

Want to discover LimbNET? 🦵

A platform created by EMBL Barcelona scientists to visualize limb development.

Explore the “Morphomovies”
👉 tuit.cat/M8Kjg

12.12.2025 12:10 👍 7 🔁 3 💬 0 📌 0
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Large language models are biased — local initiatives are fighting for change Despite advances, AI models continue to be geared towards the needs of English-speaking people in high-income countries.

Large language models are biased — local initiatives are fighting for change www.nature.com/articles/d41...

12.12.2025 11:04 👍 1 🔁 0 💬 0 📌 0

Thanks!

11.12.2025 13:31 👍 0 🔁 0 💬 0 📌 0
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A new research facility dedicated to axolotls, will be opening soon. Hosting the UK’s only dedicated axolotl research colony and will support world class studies into regeneration, ageing, cancer resistance and stem cell biology.

edin.ac/4pAAJeW

@edinuni-irr.bsky.social @aidarodrigo.bsky.social

02.12.2025 13:28 👍 10 🔁 3 💬 0 📌 2
Picture of the page of a book where there is a dedication in Spanish signed on the 27th of November, 2025

Picture of the page of a book where there is a dedication in Spanish signed on the 27th of November, 2025

What are the odds??
Yesterday I bought a book that was dedicated exactly 44 years ago!!

28.11.2025 14:39 👍 2 🔁 0 💬 0 📌 0

New paper from our lab and @friedrich-group.bsky.social !! Insights into morphogen gradient scaling to regenerate a limb at the appropriate size. #axolotl, #limbregeneration

28.11.2025 13:19 👍 28 🔁 11 💬 1 📌 0
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Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians A conserved POU4-dependent developmental program underlies mechanosensory neuron regeneration in adult planarians.

Our study on the role of the Pou4 gene in planarian neural regeneration has been published. Congratulations to the trainees and team members who led this work!

doi.org/10.7554/eLif...

20.11.2025 18:46 👍 12 🔁 5 💬 1 📌 0
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El 20 de noviembre en la Casa de las Humanidades (en Coyoacán) presentaremos este directorio ¡¡acompáñennos!!!

06.11.2025 17:01 👍 7 🔁 7 💬 0 📌 1
Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."

Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."

Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.

09.10.2025 19:00 👍 3447 🔁 774 💬 86 📌 69

Very sad news. Our group had the great fortune to collaborate with him and his group and to be inspired by his passion for science and patience for those of us not in the field. We are forever grateful to have had that opportunity.

09.10.2025 10:23 👍 4 🔁 1 💬 0 📌 0

Double Yay for regenerative biology 🥳 congrats Can 🥂!!

05.09.2025 07:42 👍 2 🔁 0 💬 1 📌 0

🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration!

How can we unlock limb regeneration in adult mammals?

It’s time to apply what we learned from 🐸 ➡️ 🐭

Thank you @erc.europa.eu for supporting ambitious science!!!

04.09.2025 13:27 👍 98 🔁 10 💬 21 📌 1

Congrats @aniaczark.bsky.social !! I am so happy for you (and the regeneration field 😉) 🥳🥳

04.09.2025 12:28 👍 3 🔁 0 💬 0 📌 0
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🥳 Congratulations to our postdoc, Dr. Anna Czarkwiani @aniaczark.bsky.social, on receiving the ERC Starting Grant @erc.europa.eu!

With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠

#CMCBnews @tudresden.bsky.social #ERCStG

04.09.2025 10:13 👍 36 🔁 13 💬 9 📌 2
receiving the ISRB2025 Distinguished Achievement Award medal in Madison (WI, USA) from Elly Tanaka, president of ISRB

receiving the ISRB2025 Distinguished Achievement Award medal in Madison (WI, USA) from Elly Tanaka, president of ISRB

#ISRB2025 I am honored and delighted to have received the Distinguished Achievement Award from International Society for Regenerative Biology for the pioneering work that we have done with my team on Hydra regeneration over the past decades!
internationalsocietyforregenerativebiology.org/page-18246

22.08.2025 16:43 👍 17 🔁 2 💬 4 📌 0

Very proud of our @canaztekin.bsky.social on his Rising Star Award 2025 from @isrbio.bsky.social! Find out more about his work on the structural limb #regeneration, specifically in understanding the differences in regeneration abilities across various species: s.gwdg.de/QidoUL #biology #maxplanck

18.08.2025 08:50 👍 29 🔁 8 💬 1 📌 0