Israel has committed genocide in the Gaza Strip, UN Commission finds GENEVA – Israel has committed genocide against Palestinians in the Gaza Strip, the UN Independent International Commission of Inquiry on the Occupied Palestinian Territory, including East Jerusalem, a...

"Israel has committed genocide in the Gaza Strip, UN Commission finds"

The UN joins other experts including the International Association of Genocide Scholars, Holocaust historians, and multitudes of lawyers in concluding this is genocide.

www.ohchr.org/en/press-rel...

Excited to share our preprint, now available online on BioRxiv! biorxiv.org/content/10.1.... We uncovered the coupling of translation and secretion machineries at the #axonalER to promote local delivery of axonal transmembrane proteins (TMPs) to the plasma membrane.

Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons - Nature Communications It is unclear how new lysosomal proteins are properly delivered in polarized neurons. Here, the authors developed a method combining the synchronization of protein release from the endoplasmic reticul...

www.nature.com/articles/s41...

POTATOMap is officially out today! (Even tho it says 2024Dec30… yeah long story😂)

Thank you to all the authors and everyone involved! I hope we have provided something useful and maybe leave a little (just a little) impact in your research.

Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins | Journal of Cell Biology | Rockefeller University Press Holmes and colleagues show that AKT activation is blocked by commonly used PIP3 biosensors, but that this can be overcome by expressing biosensors at singl

The most frequently asked question we get: do #lipidtime genetically encoded lipid biosensors compete out cells’ native effector proteins?

Victoria Holmes and Morgan Ricci led a paper in JCB that answers this question:

rupress.org/jcb/article/...

Read on for a brief thread.

Bovyn, M. J., & Haas, P. A. (2024). Shaping epithelial lumina under pressure. Biochemical Society transactions, 52(1), 331–342. #EpithelialMechanicsReview
portlandpress.com/biochemsoctrans/article/...

Heading to #CellBio2024? Do you love #lipids? Join us for an exciting subgroup on Lipids in Organelle Form and Function, Saturday at 1:45 PM! Lipid-themed happy hour to follow but you must attend the session to find out the location!

Maarten Bebelman, Lenka Belicova and Marino Zerial (left to right)

To know more about their work, we spoke to the first authors, Maarten Bebelman @mpbebelman.bsky.social and Lenka Belicova @lenkabelicova.bsky.social, and the corresponding author, Marino Zerial, Director and Scientific Member @mpicbg.bsky.social:

journals.biologists.com/dev/article/...

Lumen morphogenesis - the key to functional hepatocytes Hepatoblasts are bipotential progenitors that are destined to become either hepatocytes or cholangiocytes in the liver. Hepatocytes exhibit a unique cell polarity, called multiaxial polarity, which me...

Thanks to @dev-journal.bsky.social for writing a highlight for our paper: tinyurl.com/3aksju9f.

Thanks to all co-authors and the Vingron Lab @molgen.mpg.de and the Shevchenko Lab @mpicbg.bsky.social for the nice collaboration.

Very happy that the second paper from my postdoc
in the Zerial lab @mpicbg.bsky.social is now published in
@dev-journal.bsky.social. Together with co-first author
@lenkabelicova.bsky.social we found that apical lumen morphology influences hepatoblast differentiation. doi.org/10.1242/dev....