Kidney International

Kidney health for all: caring for people, protecting the planet

doi.org/10.1016/j.kint.2025.12.020

#OpenAccess #NephSky #MedSky #WorldKidneyDay

The relationship between obesity and chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

doi.org/10.1016/j.kint.2025.09.019

#MedSky #NephSky #OpenAccess #KDIGO #CKD #Obesity #kidneydisease

Commentary
RNA methylation in acute kidney injury: opening up new therapeutic avenues

doi.org/10.1016/j.kint.2025.12.019

Original article: doi.org/10.1016/j.kint.2025.11.010

#MedSky #NephSky #AKI #acutekidneyinjury

Histoplasma capsulatum: a rare cause of interstitial nephritis

doi.org/10.1016/j.kint.2025.07.031

#NephSky #MedSky #PathSky

Brown tumor of the patella in a long-term hemodialysis patient

doi.org/10.1016/j.kint.2025.08.045

#NephSky #MedSky #hemodialysis

Kidney Disease: Improving Global Outcomes (KDIGO): navigating a rapidly changing landscape

doi.org/10.1016/j.kint.2025.12.028

#OpenAccess #MedSky #NephSky #CKD #chronickidneydisease #KDIGO

Tubular cell-specific platelet-derived growth factor-B drives formation of fibrogenic niches in kidney fibrosis

doi.org/10.1016/j.kint.2026.01.029

#NephSky #MedSky #OpenAccess @rwth.bsky.social

Increased Smoothened signaling promotes kidney fibrosis through inhibiting autophagy in fibroblasts

doi.org/10.1016/j.kint.2026.01.028

#OpenAccess #MedSky #NephSky #renalfibrosis #kidneyfibrosis

Klotho in the kidney distal convolution regulates urinary Klotho excretion and kidney calcium reabsorption, but not phosphate homeostasis

doi.org/10.1016/j.kint.2026.01.030

#NephSky #MedSky #OpenAccess @uzh-en.bsky.social

Polygenic Risk Scores and HLA Class II Variants are Biomarkers of Corticosteroid Response in Childhood Nephrotic Syndrome

doi.org/10.1016/j.kint.2026.01.026

#NephSky #MedSky #PedsNeph #pediatricnephrology

The splenic norepinephrine–β2-adrenergic receptor axis aggravates sepsis-associated acute kidney injury via neutrophil-mediated immunosuppression

doi.org/10.1016/j.kint.2026.01.024

#MedSky #NephSky

Association between the gut microbiota and estimated glomerular filtration rate in two Swedish population-based cohorts

doi.org/10.1016/j.kint.2026.01.021

#NephSky #MedSky #OpenAccess

METTL3-targeted intervention on nuclear factors RORA/RORγt suppressing pathogenic T helper 17 cell differentiation and restores kidney damage in lupus nephritis.

doi.org/10.1016/j.kint.2026.01.025

#MedSky #NephSky

Disruption of the human cystin-1 myristoyl-electrostatic switch causes polycystic kidney disease that phenocopies autosomal recessive polycystic kidney disease

doi.org/10.1016/j.kint.2026.01.023

#MedSky #NephSky #OpenAccess @childrensphila.bsky.social

Telomere recapping via gene therapy as a beneficial strategy for cardio-renal syndrome type 4

doi.org/10.1016/j.kint.2026.01.022

#NephSky #MedSky #OpenAccess

Polygenic Risk Scores and HLA Class II Variants are Biomarkers of Corticosteroid Response in Childhood Nephrotic Syndrome

doi.org/10.1016/j.kint.2026.01.026

#NephSky #MedSky #PedsNeph
@dukemedschool.bsky.social @childrensphila.bsky.social @umnpeds.bsky.social @washunephrology.bsky.social

Brown tumor of the patella in a long-term hemodialysis patient

doi.org/10.1016/j.kint.2025.08.045

#MedSky #NephSky #hemodialysis #hyperparathyroidism

A population based, regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on healthcare and patient outcomes
doi.org/10.1016/j.kint.2026.01.019

#NephSky #MedSky
@nhsresearchscotland.org.uk @stanfordmedicine.bsky.social @ucalgarymed.bsky.social

Fibrillin-1 is a novel ligand of the epidermal growth factor receptor promoting mesangial cell activation and glomerulosclerosis

doi.org/10.1016/j.kint.2026.01.018

#MedSky #NephSky #glomerulosclerosis

Review
Targeting cellular senescence in diabetic kidney disease: potential of regenerative, cell-based therapies and other senotherapeutic approaches.

doi.org/10.1016/j.kint.2025.10.019

#NephSky #MedSky #OpenAccess #CKD #chronickidneydisease @mayoclinic.org

Bridging global kidney care gap through data: introducing the International Society of Nephrology–Global Kidney Health Atlas (ISN-GKHA) Interactive Map

doi.org/10.1016/j.kint.2025.09.013

#NephSky #MedSky #OpenAccess #kidneycare #globalkidneyhealth @theisn.org

Pericatheter vascular calcification in a long-term hemodialysis patient

doi.org/10.1016/j.kint.2025.07.042

#MedSky #NephSky #hemodialysis

Endothelial Prolyl Hydroxylase 3 Mitigates Maladaptive Inflammation to Promote Post-Ischemic Kidney Repair

doi.org/10.1016/j.kint.2026.01.017

#MedSky #NephSky #AKI #acutekidneyinjury @nu-nephrology.bsky.social @feinberg.northwestern.edu

B-cell maturation antigen-Targeted T-cell Engager Therapy Combined with B cell Depletion for Treatment of Refractory HLA Sensitization

doi.org/10.1016/j.kint.2026.01.020

#NephSky #MedSky #OpenAccess @inserm.fr @hopitalnecker.bsky.social

Nephrocalcinosis secondary to a parathyroid adenoma

doi.org/10.1016/j.kint.2025.07.030

#NephSky #MedSky #AKI #kidneybiopsy #renalpath #kidneypath

Commentary
The many faces of cholesterol in autosomal dominant polycystic kidney disease

doi.org/10.1016/j.kint.2025.11.007

Original article: doi.org/10.1016/j.kint.2025.08.037

#NephSky #MedSky #ADPKD @mayoclinic.org

Scurvy diagnosed in a patient undergoing peritoneal dialysis

doi.org/10.1016/j.kint.2025.06.026

#NephSky #MedSky #PedNeph #pediatrics

Commentary
JAG1 of all trades, master of CKD? The role of JAG1 in autosomal dominant tubulointerstitial kidney disease

doi.org/10.1016/j.kint.2025.11.006

Original article: doi.org/10.1016/j.kint.2025.08.033

#NephSky #MedSky #ADTKD #chronickidneydisease #CKD

Podocyte derived endothelin-1 and endothelial cell endothelin A receptors are essential for glomerular injury in mouse models of focal segmental glomerulosclerosis

doi.org/10.1016/j.kint.2026.01.014

#NephSky #MedSky #OpenAccess #FSGS

Commentary
Genomics of kidney volumes: one size does not fit all

doi.org/10.1016/j.kint.2025.12.003

Original article: doi.org/10.1016/j.kint.2025.08.038

#NephSky #MedSky #GWAS #kidneydisease