You can fund this proposal toward its $1k goal on ResearchHub.
Or earn $150 in $RSC by submitting a peer review.
www.researchhub.com/fund/5614/a...
You can fund this proposal toward its $1k goal on ResearchHub.
Or earn $150 in $RSC by submitting a peer review.
www.researchhub.com/fund/5614/a...
They will test it on 92 triple-negative breast cancer patients to assess whether integrated representations improve tumor microenvironment characterization beyond either modality alone.
A team from the @ohsuknight.bsky.social Cancer Institute applied for a $1k microgrant to build a reusable multi-agent MCP server that brings both into a shared embedding space.
Most AI models in biomedicine work in silos.
Histology captures tissue structure.
Spatial transcriptomics captures gene expression.
But their representations are typically analyzed separately.
Crowdfunding toward the preregistration's $10k goal is now live on ResearchHub.
Donations are tax-deductible.
www.researchhub.com/fund/5094/d...
The proposal uses AI-based de novo protein design to create binders that capture and neutralize AGEs before they trigger damage.
An application to our $10k Aging & Longevity RFP targets a quiet driver of aging: advanced glycation end products (AGEs).
These sugar-derived molecules accumulate over time and contribute to cardiovascular disease, neurodegeneration, and diabetes.
Fund this proposal toward its $5k goal on ResearchHub.
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www.researchhub.com/fund/5606/a...
AxonVoice, led by investigators at @axondao.bsky.social, proposes a $5k Phase I build to create a standardized, reproducible, AI-ready voice biomarker infrastructure.
The goal: scalable, reliable phenotyping of neurological and psychological states for research and future clinical use.
Crowdfunding toward the $10k goal is live on ResearchHub.
Donations are tax-deductible.
www.researchhub.com/fund/5532/s...
Their proposal combines Perturb-seq with single-cell aging clocks to move from correlational signatures to causal regulators.
By systematically perturbing genes and measuring shifts in aging state, they aim to produce a ranked map of aging drivers and druggable pathways.
Most aging clocks can measure biological age.
But they donβt reveal which genes to target to slow it.
A team from MIT, @ragoninstitute.bsky.social of @massgenbrigham.bsky.social, and @broadinstitute.org of @mit.edu and @harvard.edu applied to our Aging & Longevity RFP to address that gap.
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www.researchhub.com/fund/5611/r...
A research team applied to our Aging & Longevity RFP to test if gut proteins become less soluble as we age.
They compare the small intestine and colon to determine if changes differ by region.
If true, the findings could link immune metabolic remodeling to region-specific proteostasis instability.
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Neuroscience experts can submit a peer review on ResearchHub to earn $150 in $RSC.
www.researchhub.com/paper/10771...
Exercise is known to lower dementia risk.
But how exactly?
This preprint shows that aerobic activity may strengthen the brainβs smallest blood vessels.
Making them more resilient during aging and early Alzheimerβs pathology.
The preprint is live on ResearchHub.
You can read it, start a conversation, create a bounty, or tip the authors in $RSC to support the work.
www.researchhub.com/paper/99289...
Most fMRI studies rely on relatively small datasets, often just dozens or a few hundred people.
This preprint introduces NeuroSTORM, a foundation model pretrained on 28.65 million fMRI frames, over 9,000 hours of scans from 50,000+ individuals.
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www.researchhub.com/paper/15308...
It performed surprisingly well, especially at segmentation, and became competitive with minimal tuning.
The takeaway: general vision foundation models can transfer to medical imaging, reducing the need to build models from scratch.
Can an AI trained on regular photos learn to read medical scans?
Researchers put DINOv2, trained on 142M natural images, to the test across 100+ experiments on X-rays, CT, and MRI.
They asked it to detect disease and outline organs.
Biology and biochemistry experts are invited to peer review this preprint for $150 in $RSC.
www.researchhub.com/paper/11079...
Exercise clearly improves health and longevity, but the molecular signals behind it are hard to measure.
This recent study uses multi-platform plasma proteomics to track how proteins change after exercise and with long-term training.
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www.researchhub.com/paper/11080...
Many drugs for bowel disease fail because they target the wrong cells in the human gut.
To address this, researchers built an atlas of ~1 million human intestinal cells and used machine learning to identify the specific gene programs driving disease in each cell type.
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The preprint is live on ResearchHub with a peer review bounty assigned.
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www.researchhub.com/paper/10764...
This matters because gene therapies today are limited by how precisely and safely DNA can be inserted.
Improving that control could impact cancer treatments, genetic diseases, and antimicrobial design.