Boris Vauzeilles

The 2026 Honorary Fellows include Carolyn R. Bertozzi, Sir David MacMillan, Dame Margaret Brimble, Dame Clare Grey, Kelly Chibale, Jane Catherine Ngila and Sir Demis Hassabis.
See the full list: rsc.li/4qXScPv #ChemSky

#ChemBioParis2025 showed what an inclusive, united and vibrant European & global ChemBio community can achieve together.
Huge thanks to speakers, attendees, volunteers, partners and trainees for this shared success.

Something important might be taking shape next… 🧪✨

Glad to have contributed to the “Prospective in Chemistry” session at the French Academy of Sciences.
A stimulating discussion on the future of the discipline, including perspectives in chemical biology.
Many thanks to the organisers.

The #ChemBioParis2025 photo galleries are live! ✨
Take a look back at the highlights of the meeting through three sections: Speakers, Atmosphere, and Social Events.
Many thanks to our photographer, Fabien Venturi (venturifab@yahoo.fr), for capturing these great moments
👉 chembioparis2025.com/photos/

Synthetic fluorophores for live-cell fluorescence microscopy and biosensing - Nature Chemical Biology Performing live-cell microscopy experiments with high spatial and temporal resolution requires fluorophores with highly optimized properties. This Review examines the progress in developing synthetic ...

🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩‍🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...

Barcelona

Kathrin Lang is giving a fascinating closing Plenary Lecture on "Expanding the Genetic Code - New Tools for Biology" - What a conclusion for #ChemBioPhys2025 #CBCCPC25 -#ChemBioChem & #ChemPhysChem 25th anniversary - #ChemBioEurope #Happy25

Claus Seidel, at #ChemBioPhys2025, presenting FRET Spectroscopy and Nanoscopy Resolve the Structure and Dynamics of Biomolecules at the Single-Molecule Level #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Final communication of this first afternoon session is given by Jan Götze, on FRET-Based Models Unveil Functional Roles of Photosynthetic Complexes, at #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Next communication was given by Anahita Khammari, on the "Investigation of Protein-Ligand Interactions Of USP48 Inhibitors" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

"Unlocking the Secrets of Heart Muscle Structure", by Stefan Raunser #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

First talk of the afternoon, Sandrine Lévêquer-Fort is showing us her impressive developments in "Taking Advantage of Alternative Fluorescence Properties in Single Molecule Localization Microscopy" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Roman Renter, from Exciting Instruments, presenting their instrument - "Adding Dynamics to Structural Biology - Easy-to-Use Single-Molecule Tools to Bring Static Biomolecular Models to Life " #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

The next communication was given by Hsuan-Ai Chen on "Structure and Catalysis of the Alkyltransferase Ribozyme Samuri" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

This morning session continued with an Oral communication by Joseph J. BRAYMER, showing how "Yeast [FeFe]-Hydrogenase-like Protein Nar1 Binds a [2Fe-2S] Cluster" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Thank you @stephanhacker2.bsky.social, this was great session, perfectly chaired... 👍

Facscinating talk by Stephen Kent on "Racemic and Quasi-racemic Protein X-ray Crystallography Enabled by Chemical Protein Synthesis" at #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Now on stage Ezgi Karaca, for a very interesting talk on "AI Revolution in the Structure Prediction of Biomolecular Complexes" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

A very inspiring talk by Harald Schwalbe: "Following 25 Years of ChemBioChem: Towards the Development of Low Molecular Weight Inhibitors Targeting Viral RNA - A Combined NMR/Med Chem Approach" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

Today's morning session started with Gilles Gasser, presenting a stunning overview of "Radiometals in Nuclear Medicine" #ChemBioPhys2025 #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

@rubenragg.bsky.social opens the #ChemBioPhys2025 symposium in Berlin. Looking forward to two days of exciting science.

#Chemistry #ChemSky #ChemBio #Biophysics #ChemBioChem #ChemPhysChem
CC: @chemistryeurope.bsky.social

#ChemBioPhys2025 is off to a great start with a talk by Teresa Carlomagno. She talked about NMR to study the structure of proteins especially in cases, in which multiple conformation exist simultaneously. www.nature.com/articles/s41...

#ChemSky #ChemBio #Biophysics #ChemBioChem #ChemPhysChem

Inspiring talk by Johannes Broichhagen at #ChemBioPhys2025. He talked about the power of organic chemistry to optimize fluorophores for biological applications. Exciting insights into the effects of fluorophore deuteration.
pubs.rsc.org/en/content/a...
pubs.rsc.org/en/content/a...
#ChemSky #ChemBio

Great talk by @uendesfelder.bsky.social at #ChemBioPhys2025. She talked about her group's work on single molecule microscopy to study structure and dynamics in biological systems. Exciting insights into kinetochore structure and bacterial injectisome dynamics (T3SS). rupress.org/jcb/article/...

Diffraction minima resolve point scatterers at few hundredths of the wavelength - Nature Physics The central maximum of a diffraction pattern is commonly used to resolve point-like scatterers. Now spatial resolution far below the diffraction limit is achieved by using the scattering minima.

He also presented a fundamental study that allows doing super-resolution microscopy for the first time without using any ON-/OFF-state transitions. (2/2) www.nature.com/articles/s41...

Amazing talk by Nobel laureate Stefan Hell @stefanhelllabs.bsky.social at #ChemBioPhys2025. He talked about the MINFLUX super-resolution microscopy technology. Exciting applications to measuring distances between fluorophores on the single-digit nm scale. (1/2)
www.science.org/doi/10.1126/...

Interesting talk by @fragrisoni.bsky.social at #ChemBioPhys2025. She talked about her group's exciting research into exploring the vast chemical space for #DrugDiscovery using #ArtificialIntelligence in low-data scenarios. www.nature.com/articles/s43...
#ChemBio #ChemSky

The first day of #ChemBioPhys2025 comes to a close with an inspiring lecture by @lynnkamerlin.bsky.social. She talked about her group's research into the importance of conformational dynamics for enzyme engineering and #evolution. www.nature.com/articles/s41...
#ChemSky #ChemBio

Very informative talk on evolution of proteins, the last of this superb first day, by Lynn Kamerlin on "Harnessing Conformational Dynamics in Enzyme Engineering and Evolution" #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25

"Design and Synthesis of New Glycerophospholipids Probes to Explore the Lipidomic", new and original probes by Sébastien Balieu at #CBCCPC25 #ChemBioChem #ChemPhysChem #ChemistryEurope #Happy25