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Richard Sever

@richardsever

Chief Science and Strategy Officer, openRxiv. Co-Founder, bioRxiv and medRxiv.

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Latest posts by Richard Sever @richardsever

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FDA’s controversial vaccine chief will exit agency next month | CNN The US Food and Drug Administration’s head of vaccines and biologic medicines will leave the agency at the end of April, a spokesperson confirmed to CNN on Friday.

Prasad out at FDA www.cnn.com/2026/03/06/h...

07.03.2026 00:19 👍 16 🔁 3 💬 4 📌 1

I can't speak to individual papers. but emailed appeals are considered and that is the best way to go if you feel a judgment was in error. The FAQ is always handy too www.biorxiv.org/about/FAQ

06.03.2026 16:46 👍 1 🔁 0 💬 1 📌 0
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Journals and publishers crack down on research from open health data sets PLOS, Frontiers, and others announce policies trying to stem the tide of suspect research

yes - there is certainly an uptick in fairly simple analyses. we've always had a policy excluding simple analyses (BLAST search etc) but what counts as simple is tricky to define and LLMs make a lot of things more simple to do... Others are seeing this too www.science.org/content/arti...

05.03.2026 14:53 👍 2 🔁 1 💬 0 📌 0

yep - and imagine if there were dozens!

05.03.2026 14:50 👍 1 🔁 0 💬 0 📌 0
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viXra.org open e-Print archive

vixra to the rescue vixra.org

05.03.2026 12:24 👍 3 🔁 0 💬 0 📌 0

Reminder: bioRxiv's "no reviews/hypotheses" policy is something we had from the outset, because it would require subjective judgments akin to peer review (and rapid dissemination seemed less critical for this type of article). The ease of generating these with LLMs make me glad we have it. 2/n

05.03.2026 12:23 👍 27 🔁 7 💬 0 📌 0

"Non-scientists with pet theories should ideally be directed away from arXiv"

www.nature.com/articles/d41...

bioRxiv: "Hypotheses without new data...are considered out of scope and will not be posted"

www.biorxiv.org/about/FAQ 1/n

05.03.2026 12:14 👍 26 🔁 5 💬 4 📌 1
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Hey ChatGPT, write me a fictional paper: these LLMs are willing to commit academic fraud Mainstream chatbots presented varying levels of resistance to deliberate requests for fabrication, study finds.

"All major LLMs can be used to either commit academic fraud or facilitate junk science...guard rails are easily circumvented"

Is anyone surprised? www.nature.com/articles/d41...

05.03.2026 12:10 👍 13 🔁 5 💬 2 📌 0

Yep - it’s really nice to make the point that negative data are important but not all negative data are equal

04.03.2026 01:58 👍 2 🔁 0 💬 0 📌 0
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Reframing “disappointing” data at Life Science Alliance The systemic bias against negative results allows gaps and errors to persist in the scientific record - research dead ends and flawed hypotheses left unresolved. This month Life Science Alliance showc...

"Null results are essential to refutations [that] correct the scientific record...but data are not a democracy" www.life-science-alliance.org/content/9/3/...

03.03.2026 14:43 👍 9 🔁 3 💬 1 📌 0

Yes, a friend just underwent this, it is an extraordinarily difficult thing to go through, and I really wish RFK Jr would stop promoting horrific, dangerous lies about the HPV vaccine

02.03.2026 23:41 👍 24 🔁 7 💬 0 📌 0

so what/where is the image with 6p on...?

02.03.2026 18:49 👍 0 🔁 0 💬 1 📌 0
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Lack of reviewers threatens robustness of neuroscience literature Simple math suggests that small groups of scientists can significantly bias peer review.

Do low review response rates produce filter bubbles that bias fields? www.thetransmitter.org/publishing/l...

02.03.2026 16:40 👍 17 🔁 2 💬 1 📌 0
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Does the type of publisher response to integrity concerns influence subsequent citations? A cohort study. Background: Journals may respond to integrity concerns by publishing an editorial response (editorial notice, expression of concern (EoC) or retraction). We investigated whether the type of editorial ...

"little evidence retraction or editorial notice had any effect on the rate of citation"

Perpetuating signals that a paper is flawed is critical. We need to do this better systemically. In other news, people don't read papers they cite...

ht @deevybee.bsky.social

www.medrxiv.org/content/10.6...

02.03.2026 15:04 👍 21 🔁 4 💬 0 📌 1

In my simple brain, it's exciting but you need to understand the limitations: cell free systems allow you to ask q's about molecules; in vitro systems allow you to ask q's about molecules & cells; organoids may one day allow you to ask q's about mols, cells, and tissues/organs - but never organisms

01.03.2026 10:23 👍 6 🔁 3 💬 1 📌 1
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‘Unbelievably dangerous’: experts sound alarm after ChatGPT Health fails to recognise medical emergencies Study finds ChatGPT Health did not recommend a hospital visit when medically necessary in more than half of cases

"ChatGPT Health regularly misses the need for medical urgent care and frequently fails to detect suicidal ideation...we don’t know how [it] was trained...what is embedded into its models" www.theguardian.com/technology/2...

28.02.2026 03:13 👍 6 🔁 2 💬 0 📌 0
Making sure you're not a bot!

TIL the German life science portal Livivo indexes preprints www.livivo.de/app/misc/hel...

27.02.2026 16:40 👍 7 🔁 3 💬 0 📌 0

This is one of the most interesting developments as it appears that authors are now submitting preprints earlier in the process.

A reminder that our data suggests that the best time to post is approx 1 month prior to journal submission (which ~30% now are).

27.02.2026 14:31 👍 5 🔁 3 💬 0 📌 0

Yep - though GitHub is owned by Microsoft and people can remove stuff whenever they want…

27.02.2026 13:42 👍 2 🔁 0 💬 0 📌 0

When you make the cover of a high-impact journal...

27.02.2026 00:11 👍 17 🔁 1 💬 0 📌 0

the problem with email is it does not help readers. the hope is that comments can also help readers understand the strengths and weaknesses of a paper. I was just at a seminar where some of the most interesting stuff came in the Q&A. it would be great to replicate that online.

27.02.2026 00:08 👍 2 🔁 0 💬 1 📌 0

bsky.app/profile/agro...

26.02.2026 22:27 👍 0 🔁 0 💬 0 📌 0

the other challenge is maintaining those interactive formats. when this has been tried in the past, a few years alter those interactive things don't work (sadly as some of us predicted). contrast that with research data repositories, which do (for the most part) becasue the community sees value.

26.02.2026 21:09 👍 3 🔁 0 💬 1 📌 0

my feeling was data first, but my instinct is not to be prescriptive and instead build asynchrony in as a feature since it might work different for different fields, data types, etc.

26.02.2026 21:05 👍 2 🔁 0 💬 0 📌 0

This is where I think the concept of an Addendum or Follow-Up article is nice - kind of is best of both worlds. I introduced this at a journal I created years ago - not very well indexed by PubMed though (which is a problem, as ever).

26.02.2026 21:03 👍 4 🔁 0 💬 1 📌 0

💯

26.02.2026 21:01 👍 1 🔁 0 💬 0 📌 0
Post image

That ‘constellation’ model in which repos and servers collaborate to support the aspects of the ecosystem they do best is articulated here. One thing that is needed is better mapping of the graph, discovery. 3/n openrxiv.org/openrxiv-day/

26.02.2026 20:11 👍 7 🔁 2 💬 2 📌 0

IMO we can have our cake and eat it by using the Web as intended: linking a narrative (online article) with data in repositories with dedicated functionality (NCBI, image repos, PDB, etc.) such that the format limitations/archiving requirements of the former don’t constrain outputs of the latter 2/n

26.02.2026 19:47 👍 10 🔁 2 💬 1 📌 0

Huge spectrum of views on this. At one end, visions of a living 'article of the future' with embedded data in wondrous new formats. At the other, "just a PDF".

What is most interesting to me is that someone's position on that spectrum does not correlate with how tech savvy they are. 1/n

26.02.2026 19:46 👍 9 🔁 2 💬 2 📌 2

IMO we can have our cake and eat it by using the Web as intended: using links to connect a narrative (online article) with data in repositories with dedicated functionality (PDB, code hubs, NCBI, etc.). The format limitations/archiving requirements of the former then don't constrain the latter. 2/3

26.02.2026 19:41 👍 2 🔁 0 💬 0 📌 0