Dr David Vauzour

Still time to take part in this study!

I’m speaking at the Alzheimer’s Research UK Conference 2026 on How Microbial Metabolites and Polyphenols Shape Cognitive Ageing and Alzheimer’s Risk
Will I see you there?
Register here:
Registration information - Alzheimer's Research UK
#ARUKconf; @alzheimersresearchuk.org;

Full article: A novel Mediterranean diet-inspired supplement reduces hippocampal amyloid deposits and microglial activation through the modulation of the microbiota gut-brain axis in 5xFAD mice www.tandfonline.com/doi/full/10....

Still time to take part in this study!

A novel Mediterranean diet-inspired supplement reduces hippocampal amyloid deposits and microglial activation through the modulation of the microbiota gut-brain axis in 5xFAD mice Alzheimer's disease (AD) is projected to increase in prevalence, heightening the need for strategies to alleviate its neuropathological burden. The bioactive constituents of a Mediterranean-style d...

Very pleased this is now published - led by Dr Emily Connell & @dvauzour.bsky.social, we show that a Mediterranean diet-inspired supplement can improve disease signs in an Alzheimer's mouse model, acting via the gut microbiota www.tandfonline.com/doi/full/10....

🧪🧠 #gutbrainaxis #meddiet

A novel Mediterranean diet-inspired supplement reduces hippocampal amyloid deposits and microglial activation through the modulation of the microbiota gut-brain axis in 5xFAD mice Alzheimer's disease (AD) is projected to increase in prevalence, heightening the need for strategies to alleviate its neuropathological burden. The bioactive constituents of a Mediterranean-style d...

Our latest paper is online!
Here we report that a novel #Mediterranean diet-inspired supplement promotes a significant reduction in hippocampal #amyloid deposits and #neuroinflammation through the modulation of the #microbiota #gut-brain axis.

www.tandfonline.com/doi/full/10....

✅NOW RECRUITING !!!
If you are aged 18-40, live in Norwich or surrounding areas and want to test your #brain function, then see below and take part in the REACT study assessing the impact of #ginseng on #attention and #memory. @ueamedical.bsky.social @uniofeastanglia.bsky.social

The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials - GeroScience The rising prevalence of cognitive disorders highlights the urgent need for effective prevention strategies and therapeutic interventions. While adherence to a balanced diet has been associated with a...

A great collaboration with the @International Network for Evidence on Phytochemicals, Biotics for Human Health. A must read systematic review and meta-analysis on the role of #anthocyanins and anthocyanins-rich #foods on #cognitive function
link.springer.com/article/10.1...

How does your Christmas Dinner shape your gut, brain and immunity? 🎄🍽️

Join us for Feast for Thought – a festive deep dive for all with short talks and questions on food & health!

📅 11th Dec, 7pm-8pm
🎟️ Book now: feast-for-thought.eventbrite.com

#GutHealth #BrainFood #ChristmasDinner

🚨 Research Fellow Opportunity 🚨

Join @uniofeastanglia.bsky.social & @quadraminstitute.bsky.social to explore the Brain-Gut Axis.

📍 Norwich Medical School
✅ £48,822–£56,535
📅 Apply by 1 Dec

Lead pioneering research at the neuroscience–microbiome interface.

👉 vacancies.uea.ac.uk/vacancies/18...

✅NOW RECRUITING !!!
If you are aged 18-40, live in Norwich or surrounding areas and want to test your #brain function, then see below and take part in the REACT study assessing the impact of #ginseng on #attention and #memory. @ueamedical.bsky.social @uniofeastanglia.bsky.social

Building a roadmap to nutrition for Healthy Ageing: a brief report on the ILSI Europe Healthy Ageing Task Force At the end of October 2024, ILSI Europe brought together industry and academic experts from different fields to identify research gaps and challenges …

I enjoyed contributing to the @ilsieurope.bsky.social Healthy Ageing Task Force. Leonie and Thomas have done a great job summarising workshop findings on what's needed to develop nutritional interventions that support healthy ageing.

@dvauzour.bsky.social @drsimonmcarthur.bsky.social

The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: A pilot double-blind randomised crossover trial | Gut Microbiome | Cambridge Core - www.cambridge.org/core/journal...

A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the Gut-Sleep-Brain Axis randomised, double-blind, placebo-controlled pilot study https://www.medrxiv.org/content/10.1101/2025.02.20.25322405v1

Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and APOE4 genotype Abstract. Apolipoprotein E4 (APOE4) genotype and nitric oxide (NO) deficiency are risk factors for age-associated cognitive decline. The oral microbiome pl

Very pleased to see this paper out! A great collaboration with colleagues @exeter.ac.uk
Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and APOE4 genotype academic.oup.com/pnasnexus/ar...
@ueamedical.bsky.social

IGMS2025 Home Page

14th INTERNATIONAL GUT MICROBIOLOGY SYMPOSIUM - 3-5 JUNE 2025 gutmicrobiology-2025.symposium.inrae.fr

Toxin in blood of kidney disease patients could contribute to stroke risk, study suggests Scientists have revealed that a toxin found in the blood of patients with chronic kidney disease (CKD) damages the body’s protective blood–brain barrier, likely contributing to the risk of stroke.

Nice write-up of our work from NTU's press office.

@drsimonmcarthur.bsky.social @dvauzour.bsky.social

Over 7M people in the UK are estimated to live with #CKD. Researchers at #COIRM found a #gut #microbiome toxin in #CKD patients, p-cresol sulfate, damages the blood-brain barrier risking stroke & cognitive decline, but promising drugs may block this. More here: www.tandfonline.com/doi/full/10....

Just landed here from Twitter/X! 🚀 Time to rebuild my followers/following list. If u’re into microbiome science like me, let’s connect and grow a refreshed community!
🔁 Please RT & ❤️ this post so we can gather all the microbiome enthusiasts and scientists in one place. #MicrobiomeScience #Networking

New translational study from @bugsinyourguts.bsky.social and @drsimonmcarthur.bsky.social (at QMUL) showing how a microbiome-associated metabolite implicated in chronic kidney disease affects the blood–brain barrier. #microbiomesky

🧵 on our (@drsimonmcarthur.bsky.social) work showing the mechanism through which the microbiome-associated metabolite p-cresol sulfate damages the blood-brain barrier in chronic kidney disease (CKD). #microbiomesky #gutbrainaxis

Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor The gut microbiota-brain axis has been associated with the pathogenesis of numerous disorders, but the mechanism(s) underlying these links are generally poorly understood. Accumulating evidence ind...

Brand new paper from our group! www.tandfonline.com/doi/full/10.... with @bugsinyourguts.bsky.social, looking at the role of the #gutbrainaxis and the #bloodbrainbarrier in #chronickidneydisease, and how we could protect it.

Only started the work in 2016 - I blame (hand waves) everything... 1/5