Benjamín Hernández-Rodríguez

Cohesin as an essential disruptor of chromosome organization Cohesin is a multi-subunit molecular machine that is able to create lateral chromatin loops within a linear chromosome fiber. Despite intense study, a…

Plenty of work required to rigorously test the proposed hypothesis but my initial thoughts are this perspective by Adrian Bird in @cp-molcell.bsky.social may well be the most significant conceptual advance in the 3D genome organisation field in years:
www.sciencedirect.com/science/arti...

Peter MacCallum Cancer Centre https://commons.m.wikimedia.org/wiki/File:Eastern_entrance_of_the_Peter_MacCallum_Cancer_Centre_in_Parkville_(19_September_2024).jpg#mw-jump-to-license

Wrapping up my first week as a postdoc in the @meleckmas.bsky.social lab at @petermaccc.bsky.social!
Excited to be diving into epigenetic plasticity in cancer and looking forward to working with a fantastic team!

Wellcome Connecting Science laboratory and computational course Low Input Epigenomics Course dates: 9-16 May 2025 Location: Wellcome Genome Campus, UK Application and bursary deadline: 18 February 2025

🔬 Deepen Your Chromatin Insights 🧬

Strengthen your understanding of an organism's #chromatin using low-input techniques, supporting your research at both the gene and genome-wide levels.

⏰ Apply for #LowInput25 training place by 18 February!

📎bit.ly/40fdETV

#ChromatinSky @nmaziak.bsky.social

Wellcome Connecting Science laboratory and computational course. Low Input Epigenomics Course dates: 9-16 May 2025 Location: Wellcome Genome Campus, UK Application and bursary deadline: 11 February 2025

Do you want to explore the #chromatin of an organism?

Join our expert instructors at #LowInput25, and learn how to use low input techniques to support your #epigenomics research at the gene & genome-wide level

⏰Application deadline: 11 February
📎bit.ly/40fdETV

#ChromatinSky @nmaziak.bsky.social

We have had multiple discussions about why people have not previously observed the very dramatic reduction in transcription upon PNUTS depletion. So I looked at our own TT-seq data and analysed it without including the spike-in. The numbers speak for themselves! Spike-in calibration is important!

Hi Bluesky! I made a 3D chromatin starter pack.
Let me know if you would like to be added.
go.bsky.app/6tTQdqQ