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Lee Zamparo

@lzamparo

Interested in ML, comp bio, immunology, and just about anything one hop away from either.

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Latest posts by Lee Zamparo @lzamparo

Gee I wonder who could be behind this

10.03.2026 01:03 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

does the province have the authority to unilaterally cut the city out of the tripartite agreement governing Billy Bishop?

10.03.2026 01:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
'One year of failure.' The Lancet slams RFK Jr.'s first year as health chief In a scathing review, the top US medical journal's editorial board warned that the "destruction that Kennedy has wrought in 1 in office might take generations to repair."

In a scathing review, the top US medical journal's editorial board warned that the "destruction that Kennedy has wrought in 1 in office might take generations to repair."

08.03.2026 12:30 πŸ‘ 3647 πŸ” 1541 πŸ’¬ 154 πŸ“Œ 97

Another lesson: be clear when speaking about Lucky Dan

08.03.2026 14:54 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Opinion: Bluesky is a dangerous echo chamber because no one wants to hear from me, specifically

Opinion: Bluesky is a dangerous echo chamber because no one wants to hear from me, specifically

07.03.2026 00:04 πŸ‘ 1395 πŸ” 356 πŸ’¬ 8 πŸ“Œ 9

Don't build stupid artificial islands that nobody wants or needs, don't propose insane tunnel highways nobody think are feasible, do fund education adequately.

Governing ON is hard, but not that hard.

06.03.2026 16:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Unspeakably envious, looks sooooo good

06.03.2026 00:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

This *is* insane. His ignorance knows no bounds, nor does his contempt for the city. The sooner we're rid of him and back to saner governance, the better.

06.03.2026 00:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

For avoiding this, I find Scholar Inbox is an essential tool.
Are there other strategies you'll share w your lab that you can also share more broadly?

05.03.2026 21:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Such a good essay

05.03.2026 21:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I'm not sure you did miss anything important

05.03.2026 20:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
β€œRough Men Stand Ready”: Neither Churchill nor Orwell The famous quotation about Rough Men defending civilization, misattributed to Churchill, has a distant relation to something by Kipling.

Goes without saying that Orwell did not say the thing she attributed to him.

05.03.2026 19:34 πŸ‘ 23 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
Video thumbnail

A new preprint with Matthew Schmitt, @kiseokmicro.bsky.social and Vincenzo Vitelli makes a huge step forward in learning functional groups of components in complex biological systems. It's dimension reduction that speaks to biological function. www.biorxiv.org/content/10.6...

05.03.2026 12:22 πŸ‘ 38 πŸ” 22 πŸ’¬ 0 πŸ“Œ 1

!!!

05.03.2026 18:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

> (*) I noodled around with this idea on BlueSky, and intend to write much more on it at a later date.

I certainly hope so!

05.03.2026 18:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Another thought that rankles all to hell: you point out a good comparable in Petr Musa.

Maybe Jason Hernandez tried, but would it not have been less money for the same likely outcome to just try and throw $15m at FCD to buy Petr Musa? Or Dejan Jovelic from SKC for ~10m? What's the arg for $argent?

05.03.2026 17:40 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

*You* have mixed feelings about Josh Sargent on TFC? Imagine how fans feel when MLSE brass talk him up as the second coming, post-Italians.

I get they want him to feel welcome. But he hasn't played in weeks, the team aren't creating many chances for a quality 9 to convert, so it's alarming yah.

05.03.2026 17:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

That quote is certainly a faceplant. He hasn't even played a minute yet, we don't even know if this team can get him the ball enough to score, can we temper expectations? Why would you go and say something so outlandish in the recent history of Insigne & Bernardeschi?

MLSE, get it together.

05.03.2026 15:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Surely the answer is yes?

04.03.2026 21:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wishful thinking is powerful

04.03.2026 21:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As far as I get it, it's markdown instruction / guidelines all the way down

04.03.2026 17:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I don't want to seem down on COT civil servants; they make the city what it is, I enjoy the output of their labour every day. But where it's clear the city should be better, the mayor has to work, push, cajole (and now on some issues just dictate?) for that change.

04.03.2026 17:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Yes, but there are some clear directions for improvement where there's a broad public consensus (e. g more public restrooms, denser development) yet inertial resistance to be overcome (e.g Councillor Holyday, rigid civil service mgmt). The leadership's job is clear: make a consensus & get it done.

04.03.2026 17:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸ’― agree. Toronto civil service is a slow moving ship & needs someone with both popular support and political capital to invest to effect change.

That Tory instead chose to keep a status quo & slowly strangle the city, despite it being plain that it wasn't working, tells me he's a poor leader.

04.03.2026 16:58 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

This is well and truly dreadful. I'm sure these artists did their best to make it less so, but my goodness. I cannot look at it for more than second and my eyes want to desperately look anywhere else

04.03.2026 15:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The New Yorker at 100; doc on Netflix

04.03.2026 00:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Flip Q: who would play you in the WITAOD movie?

03.03.2026 23:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As do we all

03.03.2026 21:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

SJ was the big loss. His xGoals saved was basically top of the league. Rosted & Long were good (not great) at recoveries, tackles, interceptions, xG against, but the keeper is the largest change

I hope an upgrade at CB, plus their young CB prospects actually being healthy enough to play will help

03.03.2026 21:04 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank goodness

03.03.2026 20:35 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0