Yes, we use www.labguru.com for inventory and as our electronic lab book (through an institutional account)
06.03.2026 19:50
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Yes, we use www.labguru.com for inventory and as our electronic lab book (through an institutional account)
3000th clone added to our clone library. Happy weekend
I’m with you on this 😭
Sudha (@chakrapanilab.bsky.social) and Julio (@cvlab.bsky.social) are organizing the 2026 Ion Channel Gordon Research Conference: Ion Channels Across Scales — Bridging Molecular Events to Physiological Outcomes, to be held at Mount Holyoke College, July 12–17, 2026.
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Kicking off 2026 on a positive note!
Check out our latest work on developmental channelopathies.
#IonChannels #NALCN #IHPRF1
Time to sign up!
Registration for the joint FEBS/EMBO course on ion channels and transporters in Erice, Italy (May 13-19th 2026) is now open:
meetings.embo.org/event/26-ion...
Please share and repost.
Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders.
🔗 Register now: www.lorneproteins.org
The commitments in the SAFE Labs Handbook.
A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers.
buff.ly/K7CGFLV
So sad. I love his work.
To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026:
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️
Game changer, no doubt. Commercial systems will have expensive consumables I suppose, but huge savings to be made in cell culture, and many important but sparse native targets come into play.
Crispr-tagged targets from iPSC neurons, for example.
TRPC6 blind? 🤯
Congratulations to everyone involved in this amazing project!
Very grateful to have been able to attend the second-ever NALCN conference. This provided a fantastic opportunity to catch up with collaborators and meet patients and families affected by NALCN-related diseases. Huge thanks to everyone at the Channeling Hope Foundation for making this event happen!
Phosphorylation on tyrosines control key pathways in immunity, cancer, and metabolism. For the first time, we can now design proteins that specifically recognize individual phosphotyrosines, even in disordered regions. (1/8)
Preprint: www.biorxiv.org/content/10.1...
When I started working on ion channels 20+ yrs ago, I could have never imagined how many channels there are to explore! Now I’m delighted to be heading to thematic meetings on two of our favorite channels in the span of just weeks - can’t wait to catch up with the ASIC and NALCN communities!
Thanks so much for contributing to this!!
A huge thank you to everyone involved and of course @lundbeckfonden.bsky.social, @carlsbergfondet.dk and DFF for funding.
Collaborator @amelierocks.bsky.social complemented this with predictions of protein stability and conservation scores. In combination with functional work this establishes a framework for classifying suspected disease variants, which we hope will aid assessment of NALCN variant pathogenicity
@chowhanchua.bsky.social implemented use of a combination of multiple parameters derived from two-electrode voltage-clamp electrophysiology recordings. These allow us to classify LoF and GoF phenotypes and to provide mechanistic insight into the molecular mechanism underlying specific variants.
De novo and inherited NALCN variants can lead to severe developmental syndromes. Although variants of uncertain significance or presumed pathogenic variants have been studied in heterologous systems before, there is no generally accepted framework on how to assess or predict variant pathogenicity.
After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN:
www.biorxiv.org/content/10.1...
Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions!
🔗 Register here: www.lorneproteins.org/register
Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.
Adriano Senatore @utoronto.ca and colleagues explore the evolutionary origins of the sodium leak channel NALCN and its ancillary subunits FAM155/Mid1, UNC79, and UNC80. rupress.org/jgp/article/...
#Evolution #IonChannels
2nd #WSCC26 will take place in Grindelwald (Switzerland) 🚠 from 4th to 6th of February, 2026.
🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others.
💡 Submit abstracts by the 26th of September, 2025:
lnkd.in/eDhPUVKd
💻 More info:
lnkd.in/eJw9pfMz
Great to see so much exciting ion channel/membrane protein work going on in the far North!
Wonderful visit to beautiful Bergen, Norway. Big thanks to @herculeria.bsky.social for hosting and to Tim Lynagh for guiding me up the local hills
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The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞
February 8–12, 2026
Register here: www.lorneproteins.org
Congratulations to you and the team - amazing work!
