And we've got metathesis vs CuAAC in the first round - that's a 1a seed vs a 1b seed

I do have a copy of this in my lab to educate the youth. I also had to procure a dvd player they could borrow.

Congratulations!

Thunder snow/graupel in Denver! #cowx

An Amplificative Detection Approach for Autocatalytic Sensing of Ethylene Amplified sensing offers the potential for high sensitivity; however, the vast majority of molecular strategies involve stoichiometric detection and signal transduction, including numerous recent examples of systems inspired by transition-metal-catalyzed reactions. Activation of latent precatalysts by a target analyte represents an attractive strategy for detecting low-concentration species. Analyte amplification represents another attractive approach, akin to PCR-based assays. Here we report an autocatalytic detection system based on the ethylene activation of Ru–I2 olefin metathesis precatalysts. Signal transduction is amplified by both catalytic ring closing metathesis of profluorescent substrates and ethylene propagation to activate additional units of catalyst. High sensitivity is observed as a result of this dual-mode amplified detection of ethylene. Detection of endogenous ethylene from fruit and oxidation-decomposition of polyunsaturated fatty acids via lipid peroxides is demonstrated.

Out now in JACS! Our new approach to amplified ethylene detection via autocatalysis - pubs.acs.org/doi/full/10.... . Congrats to Autumn and Jaiden!

Awesome, this will be my morning read tomorrow.

Awesome to see my colleague Scott's work written up by Derek here: bsky.app/profile/dere...

Sure we do. What’s up?

Preprint of our new catalytic detection system is now up. Ethylene can trigger latent metathesis catalysts and converted into signal. Let the catalyst inspired ABS be catalysts!