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Conor McCann

@conormccann-ens

Principal Investigator at UCL in Enteric Nervous System Development and Stem Cell Therapy. All views my own https://www.ucl.ac.uk/child-health/conor-mccanns-research-group

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13.11.2024
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Latest posts by Conor McCann @conormccann-ens

https://www.lbbb2026.com/apply

https://www.lbbb2026.com/apply

πŸ“’REMINDER: The deadline to apply for LBBB2026 is Monday (2nd February)
πŸ“The meeting takes place in Fusagasuga (Colombia) 31st October - 4th November
πŸ“¬Apply Now to be part of a small meeting with big ideas
@dgnm.bsky.social

31.01.2026 08:35 πŸ‘ 3 πŸ” 5 πŸ’¬ 1 πŸ“Œ 1
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Graduate Open Events: Cell, Gene and Novel Therapies Explore our Cell, Gene and Novel Therapies MSc. Join our virtual open event to meet our Programme Directors and plan your next career step.

Thinking of studying Cell, Gene and Novel Therapies?
Join our online information session where you’ll meet our Programme Directors and find out what it’s like to study at a world-leading institution. 🌍
πŸ“… Cell, Gene and Novel Therapies MSc – 12 February, 12:00-13:00
πŸ”— Sign up: bit.ly/4bwZXah

13.01.2026 16:14 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite corrective surgery, can lead to recurrent hospitalisations and reduced quality of life throughout childhoo...

Delighted to share our paper on Hirschsprung disease outcomes in England in Frontline Gastroenterology. This work brought together multiple collaborators to explore the experiences of children with Hirschsprung disease. Thanks to all involved and a great start to 2026. fg.bmj.com/content/earl...

02.01.2026 21:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Hopefully some of this information is useful for families, clinicians and researchers to demonstrate the ongoing needs of children with Hirschsprung Disease......and highlight the need for new treatments!

20.10.2025 10:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite lifesaving surgery, can result in increased hospitalisations and a lower quality of life throughout childh...

Hot on the heels of our recent basic science preprint. Check out our preprint of a data driven study looking at Hirschsprung Disease Outcomes of children in England using ECHILD (medrxiv.org/cgi/content/...).

20.10.2025 10:28 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease Hirschsprung disease (HSCR) is a devastating congenital disorder characterised by absence of the enteric nervous system (ENS) in the distal gut. Cell therapy, using human pluripotent stem cell-derived...

Check out our lab’s new preprint (www.biorxiv.org/content/10.1...) on the consequences of ENS progenitor transplantation to mouse Hirschsprung disease explants. Delighted to continue a fruitful collaboration with
@tsakiridis.bsky.social
to develop a #celltherapy for #Hirschsprungs

17.10.2025 11:08 πŸ‘ 6 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0
INSPIRE Programme β€” HDBI - Human Development Biology Initiative

For the fourth year running, our INSPIRE Programme (hdbi.org/inspire) is welcoming A-level students to @uclchildhealth.bsky.social this week. This has been possible thanks to Wellcome Trust and Human Developmental Initiative funding, and all our volunteers. #workexperience #childheath #research

14.07.2025 06:51 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

New preprint from our group on bioRxiv, a little step towards a better understanding of how coordinated contractions develop in the human intestine. Please check it out and let us know your thoughts.

20.04.2025 11:27 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Funded PhD Project in stem cells, mechanobiology and developmental biology - the Node A BBSRC Yorkshire Bioscience DTP-funded PhD project (jointly with the group of Chris Toseland) focusing on the role of biomechanical cues in embryonic cell fate decisions using human pluripotent stem ...

Second (BBSRC Yorkshire Bioscience DTP-funded) PhD project available in our lab (jointly with
@christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...

18.11.2024 15:17 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1