Nikita Vladimirov's Avatar

Nikita Vladimirov

@nvladimus

Imaging scientist, light-sheet aficionado, #mesoSPIM developer, open source contributor. Building cool microscopes for cool people. www.mesospim.org www.github.com/nvladimus

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01.12.2024
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Latest posts by Nikita Vladimirov @nvladimus

A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.

A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.

Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx

Part of sfb1690.uni-goettingen.de to study hearing, vision, and more.

Plus, you can create pretty pictures as the one below :).

05.03.2026 10:25 πŸ‘ 19 πŸ” 14 πŸ’¬ 0 πŸ“Œ 1
This glass wafer could back up your phoneβ€”and last 10,000 years

This glass wafer could back up your phoneβ€”and last 10,000 years

Writers for the Superman, Star Trek, and Mission Impossible franchises all dreamed up the idea of storing libraries of data in glass.

Now, Microsoft researchers say they are bringing this vision closer to reality. Learn more: https://scim.ag/4cZ9aJd

05.03.2026 14:30 πŸ‘ 36 πŸ” 8 πŸ’¬ 4 πŸ“Œ 0

Indeed! I managed to generate a decent online documentation for our #mesoSPIM project in 2h, something I was procrastinating for 5 years. Feels like magic.

04.03.2026 08:41 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I have mixed feelings about the music choice, but the tutorial is NICE! Thank you!

25.02.2026 13:41 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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GitHub - saalfeldlab/lens-correct: Correcting lens-distortion in confocal stacks Correcting lens-distortion in confocal stacks. Contribute to saalfeldlab/lens-correct development by creating an account on GitHub.

If your imaging system has poorly characterized constant distortions leading to chromatic aberration, shoddy stitching, or false measurements (the answer is likely yes), you may want to give this tool a try. Native installers for Linux, Mac, Win under Releases github.com/saalfeldlab/...

20.02.2026 20:51 πŸ‘ 26 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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I used this one for sealing coverslips in contact with argessive medium (BABB), worked well for me.

12.02.2026 15:35 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Silicon sealant, the type used eg for aquariums, is extremely stable, should work for this application.

12.02.2026 06:51 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Tip: never use superglue anywhere near optics. It slowly outgasses and makes optical surfaces around it hazy. For coverslips one can use nail polish, Picodent dental glue, or silicon from hardware store.

11.02.2026 20:16 πŸ‘ 21 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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A high-resolution, easy-to-build light-sheet microscope for subcellular imaging An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.

In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...

05.02.2026 22:53 πŸ‘ 47 πŸ” 23 πŸ’¬ 1 πŸ“Œ 0
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We have two funded postdoctoral positions available. Topics encompass:

-Next gen light-sheet fluorescence microscopy instrumentation

-Structured illumination microscopy and other approaches to extend the resolution limit.

-Nonlinear microscopy combined with adaptive optics / phase conjugation

27.01.2026 22:29 πŸ‘ 51 πŸ” 25 πŸ’¬ 3 πŸ“Œ 2

Agreed. Strategic quitting is a power move that can open new opportunities. But it must be strategic, not because one is simply tired and needs a vacation.

31.12.2025 09:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Has napari helped your research this year? Why not say thank you to free and open source software by making a small donation? Every bit helps your friendly core team fix bugs and bring new features to life! CZI will match up to $75K in donations! opencollective.com/napari/donate

24.12.2025 02:59 πŸ‘ 19 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

Happy to hear that!

12.12.2025 11:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Nice work, bravo!

10.12.2025 20:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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BigVolumeBrowser: a new 3D multi volume/mesh/point clould (SMLM) data viewer Hello everyone, I’d like to share with you another 3D viewer for FIJI, BigVolumeBrowser (full documentation link). Itβ€˜s a first initial public release, so there is still space for improvements. Le...

Finally, the first public release of #BigVolumeBrowser, so after teasers, you can try it yourself. For details, please check the announcement post (1/2)
forum.image.sc/t/bigvolumeb...

21.11.2025 09:29 πŸ‘ 86 πŸ” 31 πŸ’¬ 3 πŸ“Œ 4

Your talk knocked everyone out! Everyone was speechless and could only say "wow, didn't expect that" πŸ™‚Thank you for joining us!

16.10.2025 18:48 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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The 10 Years of #mesoSPIM Symposium was a blast! πŸ”ŸπŸŽ‚The excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! πŸ’ͺβ€οΈπŸ”¬

16.10.2025 15:42 πŸ‘ 8 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope - Nature Communications Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely distributed applications in diagnostics, biosensing, and science education.

This is insane. 13 years ago we bought a million dollar #microscope to do this type of super-resolution imaging. Today, all you need is a smartphone and a few hundred bucks of off-the-shelf components 🀯

www.nature.com/articles/s41...

09.10.2025 18:36 πŸ‘ 29 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Job opportunity at the University of Zurich! πŸ“’

We are looking for a π‹πšπ›π¨π«πšπ­π¨π«π² π“πžπœπ‘π§π’πœπ’πšπ§ / π‘πžπ¬πžπšπ«πœπ‘ π€π¬π¬π’π¬π­πšπ§π­ (πŸ’πŸŽ%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.

1/3

10.10.2025 08:58 πŸ‘ 4 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

07.10.2025 12:39 πŸ‘ 62 πŸ” 80 πŸ’¬ 2 πŸ“Œ 8

We are using them in real life :) We are working on making them more readily available and user-friendly in the near future.

30.09.2025 12:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
CBIAS2025 flier, showing the conference logo, listing the topics, confirmed speakers and sponsors. On the top right corner, a QR code is available to access the registration page.

CBIAS2025 flier, showing the conference logo, listing the topics, confirmed speakers and sponsors. On the top right corner, a QR code is available to access the registration page.

The program for the #CBIAS2025 is now live – space is limited, so register now to secure your spot! 24th-25th Nov, Wellcome Trust, London (UK) - see you there!

πŸ”—β¬‡οΈ
www.crick.ac.uk/whats-on/cri...

23.09.2025 13:13 πŸ‘ 10 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

"Seems"? What's the scientific evidence? Any data supporting that? This is not science, this is someone's opinion. 🀣

23.09.2025 08:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

If there is a way in, there should be a way out.

19.09.2025 10:00 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Want to hack with ~40 motivated developers in the OME-Zarr space this fall in Zurich, November 12 - 14th? The application window for the 2025 OME-NGFF workflows hackathon is closing on September 30th! Apply here to be part of this exciting week about OME-Zarr: forms.gle/849cf2fBk1pJ...

18.09.2025 09:42 πŸ‘ 11 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0

Of course I did. So stupid, could get so rich now!

16.09.2025 15:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

14 of my papers. Where can I get a settlement check from Meta? πŸ˜…

15.09.2025 19:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

6 of my papers are on the list...

15.09.2025 13:49 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Your ICE driver was very honest, that counts for something.

29.08.2025 16:10 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Last few days to submit an abstract for #CBIAS2025 (deadline 31/08)!

We invite submissions on all topics related to #bioimageanalysis, from new software tools to discoveries made using existing methods. Early career researchers are especially encouraged to submit!

www.crick.ac.uk/whats-on/cri...

28.08.2025 09:01 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0