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Chris Schaich

@chrisschaichphd

Physiologist/epidemiologist 🎩 Study design in critical care, Alz-dementia, and heart failure πŸ«€πŸ§  New England native πŸ‚ Cat pic poster 😺

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24.12.2023
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Latest posts by Chris Schaich @chrisschaichphd

Long haired domestic calico mix Chloe (aka the Princess) sitting in my lap

Long haired domestic calico mix Chloe (aka the Princess) sitting in my lap

She’s not moving πŸ₯°

21.01.2025 16:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The tuxedo looks like Lemur!

18.01.2025 04:18 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
The Psychology of Severance | Who You Are... Without Memory
The Psychology of Severance | Who You Are... Without Memory YouTube video by Like Stories of Old

A beautiful video to watch on the dawn of Severance season 2: youtu.be/duGfOLzCWmM

17.01.2025 14:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Don’t worry, I thought the same at first but my sales rep made sure to set the record straight! It looks like it launched 2 years before SpaceX’s… no pun intended haha

02.01.2025 19:57 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Subaru Starlink is Subaru’s own service; it shares a name, but is NOT the SpaceX Starlink!

02.01.2025 19:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Still image from the movie SLC Punk (1998) of a man played by Til Schweiger holding a LaserDisc and exclaiming β€œThere’s a movie on there!”

Still image from the movie SLC Punk (1998) of a man played by Til Schweiger holding a LaserDisc and exclaiming β€œThere’s a movie on there!”

Me talking to students:

12.12.2024 13:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Assorted photos of a very fancy cat named Clementine (fostering until the in-laws notice him living at their place)

02.12.2024 21:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
DMB on stage at Mohegan Sun Arena performing Tripping Billies to open the set.

DMB on stage at Mohegan Sun Arena performing Tripping Billies to open the set.

Eat, drink, and be merry. β€˜Twas a good good time.

20.11.2024 14:21 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Long live The Whale πŸ‹πŸ’

17.11.2024 21:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
A series of pictures of my cat with his head buried in an empty bag of dry food

A series of pictures of my cat with his head buried in an empty bag of dry food

Post image Post image Post image

(Movie trailer voiceover) Something has awoken. He will stop at nothing.

One kitty.

One desire.

(Explosions)

Right now, in a kitchen near you.

16.11.2024 14:18 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Do Statins Affect Cognitive Health? A Narrative Review and Critical Analysis of the Evidence - Current Atherosclerosis Reports Purpose of Review Statins are the first-line treatment for hypercholesterolemia and play a key role in the prevention of cardiovascular disease (CVD). Current studies report mixed effects of statins o...

Did you start to feel brain-foggy after starting statin therapy? Could they affect your cognitive health? Let's review the evidence, and await exciting clinical trial results! link.springer.com/article/10.1...

12.11.2024 17:23 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Still with Wake Forest though 🎩

11.11.2024 01:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Today was a GREAT day to wake up and be a resident of the great state of Connecticut, my first time doing so in over 18 years 😁

11.11.2024 01:15 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Oh awesome, thank you @citybeautiful21.bsky.social!

11.11.2024 01:12 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Been getting an influx of followers after months of inactivity. Not that I’m complaining (hello all!) but any idea how this is happening?

10.11.2024 23:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Camera still of two stray cats getting cozy in an insulated outdoor shelter

Camera still of two stray cats getting cozy in an insulated outdoor shelter

Camera still of two stray cats getting cozy in an insulated outdoor shelter

Camera still of two stray cats getting cozy in an insulated outdoor shelter

A stray cat curled up asleep

A stray cat curled up asleep

20 years and I’m still really bad at social media. Here’s some pictures of the outdoor kitties snuggling up together last night 😻πŸ₯°

07.04.2024 14:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Mean +/- SD

04.03.2024 14:47 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Gray tabby on his back exposing floofy belly that is primed for rubs

Gray tabby on his back exposing floofy belly that is primed for rubs

We got it.

01.03.2024 14:10 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

DAT BELLY 😻 πŸ‘‹

01.03.2024 13:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Black cat and tabby cat sitting on a ledge next to each other looking down at the camera

Black cat and tabby cat sitting on a ledge next to each other looking down at the camera

β€œWe are the Watchers on the Wall.” 😺

01.03.2024 02:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Fascinating- I went to Brazil some time ago for just two weeks but stayed with a host family. It took several days for my accent to return to normal upon getting back!

25.02.2024 14:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

This is one of those no-brainer, expected findings that was, surprisingly, fairly underreported.

23.02.2024 17:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Small dense low-density lipoprotein cholesterol and coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis AbstractAims. Elevated small dense LDL cholesterol (sd-LDL-C) increases atherosclerotic cardiovascular disease (CVD) risk. Although coronary artery calcificatio

New article in print in the European Journal of Preventive Cardiology! Small dense low-density lipoprotein cholesterol and coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis πŸ§ͺ πŸ˜·πŸ’‰ πŸ«€ MedSky

23.02.2024 17:26 πŸ‘ 10 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Princess Chloe: the prettiest kitty in the world.

Princess Chloe: the prettiest kitty in the world.

Two weeks without a cat pic. I’m ashamed πŸ™€ here is Princess Chloe, the prettiest kitty in the world:

23.02.2024 04:00 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

β€œOur editorial team has reached a decision to publish the above referenced manuscript, which you recently peer reviewed and found to be fundamentally flawed, on the basis of Reviewer 1’s three-word review recommending Accept.”

19.02.2024 14:03 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
It is sometimes assumed that the presence of competing risks requires the use of a Fine-Gray model (we have seen it in referee reports), but this is not correct. The model may often be useful, but is one available option among many. Grasping the big picture for a multi-state dataset is always a challenge and we should make use of as many tools as possible. It is not always easy to jump between observed deaths, hazard rates, and lifetime risk. We are often reminded of the story of the gentleman on his 100th birthday who proclaimed that he was looking forward to many more years ahead because "I read the obituaries everyday, and you almost never see someone over 100 listed there."

It is sometimes assumed that the presence of competing risks requires the use of a Fine-Gray model (we have seen it in referee reports), but this is not correct. The model may often be useful, but is one available option among many. Grasping the big picture for a multi-state dataset is always a challenge and we should make use of as many tools as possible. It is not always easy to jump between observed deaths, hazard rates, and lifetime risk. We are often reminded of the story of the gentleman on his 100th birthday who proclaimed that he was looking forward to many more years ahead because "I read the obituaries everyday, and you almost never see someone over 100 listed there."

This reminds me of asking a room of epidemiologists to raise their hand if they've heard of the term 'selection bias' and concluding it is evidently well known by the general public.

14.02.2024 23:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
There are two problems with the pcmbad fit. The first is that it attempts to estimate the expected occurrence of plasma cell malignancy (PCM) if all other causes of death were to be disallowed. In this hypothetical world it is indeed true that many more subjects would progress to PCM (the incorrect curve is higher), but it is also not a world that any of us will ever inhabit. This author views the result in much the same light as discussions of survival after the zombie apocalypse. The second problem is that the computation for this hypothetical case is only correct if all of the competing endpoints are independent, a situation which is almost never true. We thus have an unreliable estimate of an uninteresting quantity. The competing risks curve, on the other hand, estimates the fraction of MGUS subjects who will experience PCM, a quantity sometimes known as the lifetime risk, and one which is actually observable.

From Therneau et al. (2023) Multi-state models and competing risks

There are two problems with the pcmbad fit. The first is that it attempts to estimate the expected occurrence of plasma cell malignancy (PCM) if all other causes of death were to be disallowed. In this hypothetical world it is indeed true that many more subjects would progress to PCM (the incorrect curve is higher), but it is also not a world that any of us will ever inhabit. This author views the result in much the same light as discussions of survival after the zombie apocalypse. The second problem is that the computation for this hypothetical case is only correct if all of the competing endpoints are independent, a situation which is almost never true. We thus have an unreliable estimate of an uninteresting quantity. The competing risks curve, on the other hand, estimates the fraction of MGUS subjects who will experience PCM, a quantity sometimes known as the lifetime risk, and one which is actually observable. From Therneau et al. (2023) Multi-state models and competing risks

On the importance of accounting for competing risks during the zombie apocalypse--I mean, in survival analysis:

14.02.2024 22:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Yes, usually. I think it’s interesting to read an author’s more authentic voice, which usually shines through in sections like those.

13.02.2024 01:31 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
β€œThe p-value is the probability that H0 is true, right?
β€œYes honey, that’s close enough”
β€œYour foster parents are dead”

β€œThe p-value is the probability that H0 is true, right? β€œYes honey, that’s close enough” β€œYour foster parents are dead”

Oh I love this meme format. Here’s my favorite:

11.02.2024 18:50 πŸ‘ 16 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1