π Think all white matter (WM) astrocytes are the same? Think again! π Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. π§
www.nature.com/articles/s41...
@carleton-lab
Account for the Carleton and Rodriguez laboratories at the university of Geneva, Switzerland. rodriguez-carleton-labs.unige.ch Studying claustrum and cognitive dysfunctions in neuropsychiatric disorders.
π Think all white matter (WM) astrocytes are the same? Think again! π Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. π§
www.nature.com/articles/s41...
Thanks
Thank a monkey !
No idea but I hope someone will tell us!
Dive into our latest findings on this powerful structure here: βThe claustrum is critical for maintaining working memoryβ biorxiv.org/cgi/content/...
π‘ Our recent study suggests that the claustrum could be fundamental for maintaining working memory, supporting attention, cognitive control, and more!
β¨ New findings reveal something groundbreaking: the claustrum may be the essential working memory storage hub of the brain! Could it be the βRAMβ that cortical areas rely on for complex functions? #WorkingMemory #BrainResearch
Every year during neuroanatomy practical classes, medical students ask the same questions: "What is this structure located between the insula and the putamen? Is it part of the basal ganglia involved in motor control?
This work would not have been possible without the dedicated, collaborative efforts of my colleagues, Madlaina Boillat and Marie Moulinier, from the @carleton-lab.bsky.social labs. 9/9
We are hiring TWO Assistant Professors!!! Please share!!
neurojobs.sfn.org/job/38211/tw...
π§© Our findings provide a detailed cellular map of the claustro-insular region and offer new insights into how Nr4a2 regulates the molecular identity of its neurons.
www.biorxiv.org/content/10.1...
π This shift involved activating a transcription factor cascade, resulting in altered neuronal firing patterns. This suggests NR4A2 acts as a master regulator of claustrum neuron identities and influences their functional dynamics. β‘ #NeuronalFunction
π§ We focused on NR4A2, a gene linked to neuropsychiatric risk and highly expressed in the claustro-insular region. Using an Nr4a2 haploinsufficiency model, we found that only claustrum neurons showed shifts in molecular identity. π§© #Genetics
π§« By combining single-cell RNA sequencing with spatial transcriptomics, we created an atlas of the claustro-insular region in mice. This approach unveiled diverse neuronal subtypes and unexpected complexity. π #BrainAtlas
π The claustro-insular region: a critical but poorly understood part of the brain, known for its roles in attention, cognitive flexibility, interoception, and affective processing. Our recent research provides a new, high-resolution map of this fascinating area.