Sebastian S. Cocioba's Avatar

Sebastian S. Cocioba

@atinygreencell

Flower Designer at Neoplants 🌺 Researcher at Binomica Labs Degreeless Heathen Petunia and Snapdragon Breeder Open Lab Notebook: http://tinyurl.com/ATGCFFE

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Latest posts by Sebastian S. Cocioba @atinygreencell

Getting ready for my quarterly trip to Neoplants HQ in Paris end of month. This quarter went by SO FAST. We got a new intern and I'm so jealous of their cool projects. Critical path work but in a safe sandbox where they can make mistakes and learn. Wish I had that growing up, lol

05.03.2026 02:18 πŸ‘ 8 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Exapted CRISPR–Cas12f homologues drive RNA-guided transcription - Nature Specialized Οƒ factors interact with nuclease-dead, CRISPR–Cas12f proteins to form potent, RNA-guided gene activation systems that function independently of fixed promoter motifs.

Just amazing what evolution can come up with. Naturally occurring nuclease deficient Cas12 family members use gRNAs to bind DNA and recruit sigmaE family members that drive txn initiation proximally. 2 papers! 1- describes 2- structure!
www.nature.com/articles/s41... www.nature.com/articles/s41...

04.03.2026 17:06 πŸ‘ 38 πŸ” 21 πŸ’¬ 0 πŸ“Œ 2
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Trump’s War on Iran Could Screw Over US Farmers The Middle East supplies a huge amount of the world’s fertilizer. Conflict in the region has sent prices soaring ahead of the critical spring planting season.

there's a lot going on right now but did you know a massive amount of the world's fertilizer flows through the middle east, and did you know that that fertilizer needs to be shipped to the us *right now* for planting season, and uh did you know we are at war with iran

04.03.2026 19:10 πŸ‘ 1386 πŸ” 597 πŸ’¬ 83 πŸ“Œ 112
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My babies. Alice F5, Snapdragon Ultradark F1, Snapdragon White F1.

Can't wait to see these blooms and start another round of selection. Plant breeding is such unique peace.

04.03.2026 18:41 πŸ‘ 15 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Jags' lab has a very interesting project you ought to check out if you're a fan of synthetic microbial communities and the emergent weirdness therein. Gonna follow this one closely for sure!

03.03.2026 16:24 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

@bielleogy.bsky.social πŸ‘€

02.03.2026 17:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Calibrating for absolute microbiome abundances without spike-ins www.biorxiv.org/content/10.6... #jcampubs

02.03.2026 17:18 πŸ‘ 8 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
Rescue workers retrieve bodies from rubble in deadly strike on girl's school in Iran | DW News
Rescue workers retrieve bodies from rubble in deadly strike on girl's school in Iran | DW News YouTube video by DW News

Is this fake, Amir?

youtu.be/61FKMTbm3X0?...

02.03.2026 12:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

en.wikipedia.org/wiki/File:Se...

Why does this align with the same place on google earth and have the same drawings on the walls and show the schoolbags of children? This is getting very dark, Amir. You do know I was holding the USA accountable in my post, right? Reread my post please before accuse

02.03.2026 12:54 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Thats an extremely grave accusation.

02.03.2026 12:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

You missed my point entirely. I am criticizing the US government for misplacing a bomb, giving no notice to Iranian citizens, and acting without congressional approval. Please dont take my works and twist them.

02.03.2026 12:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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More Than 100 Reported Killed in Strike on Girls’ School in Iran The strike hit the school during the first wave of strikes around 10 am on Saturday morning, the start of the school week

time.com/7381982/iran...

t.me/farsna/413704

If the us govt and israel and factnameh and telegram video align with the claim then what do we do? I guess the killing of the Ayatollah also not confirmed by independent sources too. See the video.

How do you know this did not happen?

02.03.2026 12:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Please google the story to see the updates

02.03.2026 00:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Im failing to understand where the issue is in what is being corroborated by multiple agencies now and Israel is shirking blame for it. I understand your issue in principle but google the news pls.

02.03.2026 00:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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All girls school in Iran struck by US-Israeli strike, over 100 casualties The death toll at an all girls school in southern Iran struck by a US-Israel strike is over 100, according to the state-run IRNA news agency. U.S.

apnews.com/video/all-gi...

Its in the AP and several other agencies.

01.03.2026 17:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

If you must declare your war then declare it and let civs evacuate long before the first bombs drop. What the actual fuck is this bullshit. You're telling me Israel couldsend a missle into the side of an apartment building and only hit its target, but we somehow precision-bombed a school full o kids

28.02.2026 16:08 πŸ‘ 28 πŸ” 5 πŸ’¬ 3 πŸ“Œ 0
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PokΓ©mon turns 30 β€” how the fictional pocket monsters shaped science The Japanese media sensation has inspired generations of researchers in fields as diverse as evolution, biodiversity and research integrity.

I can say with full confidence that engaging with Pokemon games as a child laid the foundation for my interest in the living world, of exploring biological systems, and curration of living collections. I am who I am today in part due to this game.

www.nature.com/articles/d41...

27.02.2026 18:15 πŸ‘ 29 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0

here are the primers if anyone is interested:

>PetHyb-UBQ10-CLOSE-F
5'-tttccatttccaccttaacttgtaattagt-'3

>PetHyb-UBQ10-CLOSE-R
5'-gatgtggtctcttaaaattagttagctcat-'3

Enjoyyyyy

27.02.2026 17:57 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Inadvertently found the most thermodynamically ideal (according to Primer3) primer pairs I have ever seen, lol. Trying to isolate the UBQ10 region of a different petunia line and the ones that flank the presumed regions of interest give almost zero penalty score!

27.02.2026 17:57 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Medioctrity loves arrogance.

27.02.2026 05:48 πŸ‘ 9 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Duckweed so elegant

27.02.2026 04:37 πŸ‘ 25 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
He-Man & the Masters of the Universe: Dragon Pearl of Destruction Gameplay Trailer | IGN Fan Fest 26
He-Man & the Masters of the Universe: Dragon Pearl of Destruction Gameplay Trailer | IGN Fan Fest 26 YouTube video by IGN

We are in the strangest timeline, and its mostly bad, but at least there are some amazing games coming out this year. Look at this pixelart glory. Can't wait to grab my hommies and play in two months. Pre-ordering asap.

www.youtube.com/watch?v=D37C...

26.02.2026 23:10 πŸ‘ 6 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Welcome to the world, little spark. You are loved. πŸ’š

26.02.2026 18:10 πŸ‘ 21 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

I lost my crop to spider mites unfortunately. But i have seed.

26.02.2026 17:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Grow light*

26.02.2026 14:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I begged them to ship alongside a grow kight but no one listens. Petunias are not houseplants and need supplemental light to survive. My glowy petunias did really well under 16hr days with full spectrum grow lights but poorly on sill

26.02.2026 14:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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Jefferson Lab Tapped to Lead Technology Development for Exploring Nuclear Waste Treatment Options Particle accelerator technologies, such as this niobium-tin particle accelerator cavity, are inspiring efforts to reduce the radioactivity of nuclear waste while also using it to generate electricity.

Thrilled for this.

www.jlab.org/news/release...

26.02.2026 00:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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I absolutely love how the house paint looks against fresh snow. Neighbors said it would be too dark but everyone passing by gave compliments on the bold choice. Whole hood is gray and beige. Moscow Midnight by Sherwin Williams is gorgeous.

25.02.2026 19:58 πŸ‘ 29 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

The profession of science seems to get in the way of science these days. Hard to decouple hiring metrics from the science when its a job people compete for. Not sure there is a good alternative that wont initially destabilize academia rn

25.02.2026 17:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

That's so wildly unethical and a dereliction of duty as a researcher. The whole point of science is the generation of knowledge, and a purposefully obfuscated contribution is fraud which should come with grave consequences. What the fehk are we doing here otherwise? Why bother with rigor at all?

25.02.2026 08:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0