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Matt Olm

@mattolm

Assistant Professor at CU Boulder Studying the human microbiome https://www.colorado.edu/lab/olm/

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29.09.2023
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Latest posts by Matt Olm @mattolm

Excited to share great work from @jingqian.bsky.social , now a second year graduate student in my lab, from research she conducted at her previous position at Shanghai Jiao Tong University!

06.03.2026 19:28 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Evaluation of antimicrobial resistance governance across 193 countries to inform the 2026 Global Action Plan update - Nature Medicine An evaluation across 193 countries for the 2026 Global Action Plan update showed that countries with strong multisectoral governance and early surveillance adoption achieved long-term improvements in ...

Excited to share our new paper in @natmed.nature.com ! We evaluated AMR governance across all 193 countries to inform the 2026 Global Action Plan update. A massive collaborative effort - proud to contribute to this critical global health challenge. πŸ₯³

doi.org/10.1038/s415...

06.03.2026 18:40 πŸ‘ 4 πŸ” 1 πŸ’¬ 2 πŸ“Œ 1
EBAME workshop EBAME - Computational Microbial Ecogenomics Workshop

Interested in developing your skills in microbial 'omics? Consider joining us in Brest πŸ‡«πŸ‡·, Oct. 10-24 for two weeks of intensive lectures an tutorial from top faculties and TA! maignienlab.gitlab.io/ebame/
Bonus: beautiful seascape and friendly spirit!

16.02.2026 10:03 πŸ‘ 9 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

I've long respected Peer Bork's work as top-
tier in the field and always hoped to get to chat with him at a conference someday. Very sad to see this.

16.01.2026 20:31 πŸ‘ 9 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Really great answer and thanks for taking the time to respond! I agree a super interesting field and love to see work like the paper you just published making the picture more and more clear over time

09.01.2026 21:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Cool paper! Thanks for sharing. As an outside observer I’ve always wondered if the microbes in breast milk could all be from the skin around the nipple (infant oral microbiome + adult skin), or if there’s evidence they’re resident in breast tissue / come from elsewhere. Any thoughts as an expert?

09.01.2026 14:23 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

All you want for christmas is.... transposon mutagenesis!

Our new work at @cultivarium.bsky.social screening lots of transposon vectors in lots of bacteria, from @charliegilbert.bsky.social and team.

Transposon and promoter modular parts available on Addgene (pooled library will be there soon too)

24.12.2025 15:03 πŸ‘ 84 πŸ” 32 πŸ’¬ 1 πŸ“Œ 1
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Just got back from an incredible trip to Aga Khan University in Karachi, Pakistan, where I led a 3-day workshop on microbiome bioinformatics. I was blown away by the students, the research facilities (both on the Karachi campus and at the rural Matiari field site), and the hospitality of my hosts!

13.12.2025 16:59 πŸ‘ 6 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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πŸ“’ New preprint is out on bioRxiv πŸ“’:

How much does virome prep influence our view of the human gut virome?

Short answer: a lot.

Long answer:
doi.org/10.1101/2025...

Different methods lead to distinct community structures, richness, and major virus-host abundance patterns.

🧡 1/5

27.11.2025 20:44 πŸ‘ 26 πŸ” 13 πŸ’¬ 2 πŸ“Œ 0

Very happy to share our recent work @cultivarium.bsky.social on genetic tools for Ideonella sakaiensis, a (Betaproteo-)bacterium that degrades PET plastic.

We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.

12.11.2025 19:05 πŸ‘ 79 πŸ” 38 πŸ’¬ 5 πŸ“Œ 3
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One simple trick that statisticians hate If you don't like the results, just ignore the control group

A lifehack for turning "non-significant" results into pure gold?

(ICYMI)

statsepi.substack.com/p/one-simple...

30.10.2025 10:29 πŸ‘ 61 πŸ” 13 πŸ’¬ 9 πŸ“Œ 1

The one year anniversary of my arrival at UBC flew by a month ago. Thanks to fellow newPI and former grad school pal @mattolm.bsky.social for reminding me of one of the biggest lessons I’ve learned this past year: *make* time to reflect! Here are some reflections on my first year as a PI & prof… 🧡

29.10.2025 15:48 πŸ‘ 15 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Overall, after a year, I’m really happy with where the lab’s at. It feels like we’ve gone from a blank room (and empty hard drive) to a functioning research ecosystem. Can’t wait to start publishing to share our results with the world, and I’m so thankful to all my amazing lab members!

28.10.2025 13:48 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Another surprise is actually the sheer number of meetings. But they’re also more varied and interesting than I expected; a mix of mentoring, working on research problems, and discussing new ideas with potential collaborators all the time.

28.10.2025 13:48 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Work/life balance is also better than I expected. Having a toddler at home probably helps with this though, as I don’t really have the option to work late even if I wanted to! There have only been once or twice where deadlines have forced a short period of late nights and grueling hours.

28.10.2025 13:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Transitioning from doing research myself to mentoring others in completing that research has been more challenging than expected, but it’s amazing to get to see data appear without doing any of the hard work of generating it!

28.10.2025 13:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Overall it’s a total joy, and in almost every way just as fun as I had hoped it would be πŸ˜€. Getting to satisfy my curiosity on a daily basis while contributing to the global scientific enterprise and working with the next generation of scientists is just an incredible way to spend my days.

28.10.2025 13:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I have officially been a professor for just over a year! I’ve been reflecting on what this first year has been like and wanted to share a few thoughts on how it compares to the expectations I had when I decided to pursue this career over a decade ago.

28.10.2025 13:48 πŸ‘ 22 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely.
jobs.colorado.edu/jobs/JobDeta...

17.10.2025 15:59 πŸ‘ 37 πŸ” 39 πŸ’¬ 0 πŸ“Œ 0

Thanks, @zaminiqbal.bsky.social - very glad to see this out! A great contribution

10.09.2025 22:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Wow so impressive!

30.08.2025 00:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I reviewed this paper a bit ago and have been waiting for it to come out. A great resource for us Bifidobacteria researchers!

17.07.2025 01:44 πŸ‘ 21 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

Cool paper, I appreciate how they compare observed vs expected breadth of coverage.

Missing phylogenetics, could be very interesting to genotype and/or assemble some of these pathogens if coverage is high enough

13.07.2025 19:19 πŸ‘ 21 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1
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Do people in the same household share strains when they have the same species?

How many cells transmit when a strain is shared?
Can strain composition be dynamic when species composition is stable?

We answer these and related questions for the facial skin microbiome in our latest paper.

🧡[1/10]

01.05.2025 18:41 πŸ‘ 140 πŸ” 67 πŸ’¬ 4 πŸ“Œ 1
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Assemblies of long-read metagenomes suffer from diverse errors Genomes from metagenomes have revolutionised our understanding of microbial diversity, ecology, and evolution, propelling advances in basic science, biomedicine, and biotechnology. Assembly algorithms...

I am very happy (and anxious) to share with you our most recent work in which we evaluated four of the most popular long-read assemblers,

www.biorxiv.org/content/10.1...

and tell you just a little bit about it in the following 🧡

28.04.2025 08:07 πŸ‘ 137 πŸ” 73 πŸ’¬ 5 πŸ“Œ 8

Many pregnant women in rural #BurkinaFaso struggle to eat enough to meet the demands of their growing babies. This leads to higher rates of #miscarriage, still- and #preterm birth, and intrauterine growth restriction.

25.03.2025 11:58 πŸ‘ 11 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0
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Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial Nature Communications - Here, in a sub-study of the MISAME-III randomized controlled trial, the authors show that maternal balanced energy-protein supplementation during pregnancy and lactation...

Just yesterday, we published a deep dive into the physiological effects of #BEP supplementation on both mom and baby: rdcu.be/ed5Wb πŸ₯°

25.03.2025 11:58 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Good thread and good accompanying article. The conceptualization of all Alzheimer's research as a monolith of closed minded thought based on fraud is just a myth that doesn't stand up to scrutiny

www.statnews.com/2025/02/14/a...

05.03.2025 22:55 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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The University of Pittsburgh pauses its Ph.D. admissions process amid research funding uncertainty A spokesperson for the University told WESA Friday that the school has "temporarily paused additional Ph.D. offers of admission," while Pitt works to understand how proposed federal funding cuts could...

The University of Pittsburgh confirmed Friday that there would be no new Ph.D. offers of admission while Pitt works to understand how reduced federal aid could impact the institution.

21.02.2025 21:56 πŸ‘ 1194 πŸ” 770 πŸ’¬ 55 πŸ“Œ 347

good news, finally submitted my grant to nsf on Technical biases in quantifying the inclusive fitness of minority alleles under diversifying selection in diverse microbial communities

04.02.2025 04:05 πŸ‘ 377 πŸ” 42 πŸ’¬ 17 πŸ“Œ 8