Doug Greig 😷 🇨🇦

In conclusion, the serum proteome in ME/CFS reveals a distinct pattern characterized by reduced release of intracellular proteins and increased secretion of extracellular proteins, indicating widespread tissue involvement and disturbed systemic homeostasis. These changes point to altered metabolic and inflammatory regulation across multiple organs, including skeletal muscle, brain, and bone marrow. The accompanying immune dysregulation and attenuated neutrophil function, further supports the notion of a sustained, multisystem imbalance involving immune, vascular, and metabolic processes. Together, these findings offer molecular insight into ME/CFS pathophysiology and a foundation for future biomarker and therapeutic development.

www.cell.com/cell-reports...

#MECFS

From the OMF-supported Medical Education Resource Center (MERC) with @batemanhornecenter.bsky.social ⬇️

And reminder to all Albertans angry and afraid about what is going to happen, a reminder that the gov. is devastating your disabled neighbours NOW. Disabled people unable to work (14 years for me) will receive details in coming weeks about being forced onto work programs for less support.

When governments ignore all legal avenues of dissent, maybe “progressives” will finally realize that direct action, community organizing, mutual aid, and caring for/protecting your most vulnerable neighbours first and foremost is the only way forward.

There’s no voting our way out of where we are.

OMF graphic recognizing National Caregivers Day on February 20.

OMF honors and recognizes the dedication of caregivers who provide daily support, advocacy, and stand beside loved ones living with #MECFS, #LongCOVID, and related diseases.

To every caregiver: thank you. You make a difference. You matter.💙

A professional portrait of Dr. Armstrong in an office setting, alongside text announcing nearly $1M awarded to the OMF Melbourne ME/CFS Collaboration.

Dr. Christopher Armstrong and his team at OMF's Melbourne ME/CFS Collaboration have been awarded nearly $1 million through the Australian government’s Medical Research Future Fund (MRFF) for the project Energy inefficiency in #LongCOVID and #MECFS.

👉 Learn more: https://ow.ly/hj9F50Yh6TY

deadder.substack.com

a meme — the top says “My dog just got a haircut and now he looks like he gave up drinking and got his life together” and underneath are 2 photos of a dog (a schnauzer i think?). on the left, the “before,” he’s scruffy and in need of a haircut and a bath. and on the right, the “after,” he’s clean and clipped and wearing a jaunty red bow tie and looking very dapper indeed.

i don’t know if it’s the jaunty bow tie or what but i cannot stop laughing at this

Schnauzer with the words Fuck Ice

TRIGGER WARNING, because here is a US Marshal from Trump‘s Gestapo Force in Memphis kicking a puppy today in the Whitehaven neighborhood and breaking its rib. They were serving a warrant and I guess BIG MAN got scared of the schnauzer.

(I didn’t take the video, the dog’s person did)

Graphic titled “Reading Scientific Papers”. A person wearing a white lab coat sits at a desk, holding a blue pen and reviewing printed research papers. A blue button reads “Science Wednesdays.”

📑 Scientific papers typically include: abstract, introduction, methods, results & discussion. TIP: use the abstract, look at the figures for the results, form your own conclusion, then read the discussion.

👉 Reading scientific papers: www.omf.ngo/scientific-p...

An ecologist “lives alone in a world of wounds…. [He] must either harden his shell and make believe that the consequences of science are none of his business, or he must be the doctor who sees the marks of death in a community that believes itself well and does not want to be told otherwise.”

🌱🐋🌎🧪

Photo of Leopold in horseback. The Wilderness Society.

Aldo Leopold was born OTD in 1887.

“We abuse land because we see it as a commodity belonging to us. When we see land as a community to which we belong, we may begin to use it with love and respect.”

#HpBio #HistSTM 🌎 #philsci #STS 🧪

... "The NINDS Director had periodically been criticized, particularly by those with long COVID or myalgic encephalomyelitis/chronic fatigue syndrome, for what they saw as a disregard for these conditions."

All text image against cream background. Text: " 2026 Word of the Year Care Noun: “the provision of what is necessary for the health, welfare, maintenance, and protection of someone or something” and “serious attention or consideration applied to doing something correctly or to avoid damage or risk.” Verb: “feel concern or interest; attach importance to something” and “look after and provide for the needs of.”

Does anyone try to choose a word of the year?

I do not. I am not good at “give a one word answer” type actions. I am more… how about a nice paragraph…perhaps a short essay type person.

However, today as I was pondering this question one word did come to me- care.

#pwME #NewYear #care

Evidence-Informed Decision Making Casebook Project | National Collaborating Centre for Methods and Tools www.nccmt.ca/impact/user-...

Do you or your team have a success story involving evidence-informed decision making (EIDM)?
If so, we would love to hear from you!

Wishing everyone a happy new year and we will be forging ahead in 2026 with renewed energy to find answers for people living with #LongCOVID, #MECFS, chronic #lyme and other infection-associated chronic conditions and illnesses. Speaking for myself, here are some questions I
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COVID-19 Is Six Today. What We’ve Learned | The Tyee We need cleaner air, which requires changes in medical culture.

If @thetyee.ca continues to publish excellent articles like this in 2026 - addressing an #OngoingPandemic of an injurious #AirborneVirus - I'll renew my subscription (cancelled a couple of years ago, when the 🇨🇦 #Media outlet began to ignore #COVID) -

@crof.bsky.social 🙏

thetyee.ca/Analysis/202...

A four panel cartoon by Nathan Pyle. First, an adult putting up decorations tells a young one “We celebrate because we completed a revolution around the star.” Second, the young one comments “So it is identical to emergence day?” And the adult replies “Emergence day is for one individual’s survival”. In panel three, the adult continues “New Revolution’s Day celebrates collective survival.” “Oh” says the young one. The final panel shows the adult and young one, both wearing comical hats striped in spirals, with their arms high. The young one says “We did not die!”. The adult replies “Exactly”.

Happy New Revolutions Day. We did not die!

A brunch of liberals, specifically Jon Stewart, Jon Favrou, & Tim Miller, threw a temper tantrum on one of their WFH podcast, because masks & people like Judah Friedlander who made masking a healthy habit like brushing teeth, terrifies & shames them

HAPPY NEW YEAR 🎊

Hey Jon Stewart, jokes about wearing masks aren't funny Critics of the host say he's a hypocrite.

www.motherjones.com/politics/202...

Key highlights from 2025: 40 active research projects underway; 16 new scientific publications and one preprint; StudyME registry with over 14,500 participants supporting 21 studies worldwide; launch of BioQuest, the largest biomarker discovery study in ME/CFS research; progress in the Life Improvement Trial (LIFT); and release of a Clinical Care Guide for ME/CFS and Long COVID through the Medical Education Resource Center.

Because of our community, 2025 moved the field forward. Since 2012: $60M+ raised, 76 projects, 53 publications.

With just a few days left in 2025, will you consider making a gift? A year-end gift keeps research moving. Donate hope today👉 www.omf.ngo?form=donatenow

If you didn’t watch the third and last day of the #ICanCME2025 Conference for ME/CFS, here’s the live tweeting stream by @spichaksimon.bsky.social. Thanks, Simon, and thanks to @icancmeresearch.bsky.social for such a brilliant conference.

🌍 People worldwide used their limited energy to finish “ME/CFS is…” Their voices show the challenges, losses & urgent need for change. Thanks to matching donors, every gift to OMF is tripled up to $500K!

👉 Donate: www.omf.ngo?form=donate-....

#mecfs #pwME #mecfsresearch

CBC’s Flagship Program Platforms “Quackery” for Long COVID CBC's national broadcast aired an interview with Gill Deacon about her Long COVID recovery. Deacon used an unproven program called the Lightning Process that's been criticized for exploiting patients ...

Earlier this week, the CBC broadcast an interview with Gill Deacon, discussing her Long COVID recovery using brain retraining.

They didn't tell you the specific brain retraining program, the Lightning Process, has been accused of exploiting patients.

simonspichak.beehiiv.com/p/cbc-flagsh...

1/n

At the #ICanCME2025 conference today!

Sabrina Poirier & Maeghan Taverner's intros blew me away.

~Acknowledging labor from people with lived experience
~Setting out expectations
~Moment of silence for those we've lost

This is what a conference designed by people with lived experience looks like 🧪

A photo showing the Canadian Collaborative Conference on ME program for November 04

Join us tomorrow online at the Canadian Collaborative conference on Myalgic Encephalomyelitis (ME)! I will be talking a bit about Cognitive Dysfunction in ME and the lessons we have been learning from Long Covid research.

Free registration here: icancme.ca/research/202...

#ME #LongCovid

"Nothing About Us Without Us".
I've been thinking about the title of this meeting and asking myself, why don't we hold more scientific meetings like this? The public brings the questions for the scientists, and we show them what we are doing to address it. #ME #MECFS
#AcademicSky

A person wearing an orange shirt is standing indoors, leaning slightly against a wall, and covering their eyes with one hand as if feeling dizzy. Below the image, text reads: “Living with Orthostatic Intolerance (OI)” followed by a quote: “If everyday tasks like standing in line or taking a shower leave you dizzy, exhausted, or foggy, you’re not alone.” — Melanie Hoppers, MD.

From the OMF-Supported Medical Education Resource Center (MERC) at Bateman Horne Center:

Orthostatic intolerance & #POTS are common in #MECFS & #LongCOVID. Learn signs + management tips: ow.ly/iz3b50Xb2QJ

#POTSAwarenessMonth #UnitedForME @batemanhornecenter.bsky.social