Amanda Randles  πŸ§ͺβš›οΈ πŸ‘©β€πŸ”¬'s Avatar

Amanda Randles πŸ§ͺβš›οΈ πŸ‘©β€πŸ”¬

@profamandarandles

Director of the Duke University Center for Computational and Digital Health Innovation. Alfred Winborne Mordecai and Victoria Stover Mordecai Associate Professor of Biomedical Engineering. Research in HPC and digital twins for health.

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Latest posts by Amanda Randles πŸ§ͺβš›οΈ πŸ‘©β€πŸ”¬ @profamandarandles

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Speaking at SIAM Conference on Parallel Processing for Scientific Computing this week about vascular digital twins and the role of high performance computing in understanding physiology over time.

Great conversations with the SIAM community. Thanks for the invite!

#SIAMPP26

04.03.2026 21:02 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Sharing this ema, a traditional wish plaque from a Japanese temple, that we made while attending the Sony Women in Technology Award with Nature for women in science and technology. Returning as keynote speaker after being an inaugural winner in 2025 was especially meaningful.

24.02.2026 03:37 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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High-throughput adaptive physics refinement for tissue-scale adhesive dynamics Explicitly resolving ligand–receptor interactions of circulating tumor cells (CTCs) across anatomically realistic vasculature remains computationally …

πŸ§ͺβš›οΈ Tracking thousands of circulating tumor cells at tissue scale is now tractable with a GPU based adaptive framework. Check out our latest paper: www.sciencedirect.com/science/arti...

23.02.2026 17:10 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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From Monitoring to Prediction: How Cardiovascular Digital Twins Could Transform Arrhythmia Care Amanda Randles, PhD,Β explores how cardiovascular β€œdigital twins” could move arrhythmia care beyond reactive monitoring toward proactive, personalized management.

What if arrhythmia care moved from detecting events to anticipating risk? I spoke with Jodie Elrod and the EP Lab Digest team about how cardiovascular digital twins could inform prediction and personalized decisions.

13.02.2026 04:47 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Seminar Series | Biomedical Engineering Biomedical Engineering Department at Stony Brook University

Great time giving the BME Seminar at Stony Brook University SUNY. Loved the digital twin discussion and the insightful students. Thanks Yi-Xian Qin!

06.02.2026 03:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Interested in AI in healthcare? Learn how large language models can be used responsibly. Virtual seminar Jan 21, 3–4 PM.

20.01.2026 15:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Come learn about the new Duke Certificate in Computational & Digital Health! Jan 20, 12–1 PM, Bseisu CafΓ©, Wilkinson.

20.01.2026 14:59 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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So proud of my PhD student Dr. Aristotle Martin on his successful defense this week. A joy to mentor him and excited to see what he does next.

@dukeengineering.bsky.social @dukeubme.bsky.social

13.12.2025 14:46 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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You’d think HF monitoring must be invasiveβ€”but our digital twin predicts pressures noninvasively. A step toward proactive heart care.

Paper: comphealth.duke.edu/publications...

04.12.2025 15:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Happening now! Interest in AI + HPC? Check out the ongoing seminar from a leader in the field.

04.12.2025 14:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Revisiting a favorite seminar! @john-hickey.bsky.social shows how DNA barcodes reveal multicell structure and tissue networks. Watch the full talk now: comphealth.duke.edu/event/from-c....

02.12.2025 17:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us Dec. 4 as Dr. Yang You shares breakthroughs in fast, efficient large-scale AI, from LAMB and LARS to new parallelism and real-time generative models.

02.12.2025 17:11 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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And a huge congrats to Aristotle Martin for earning an Honorable Mention for the George Michael Memorial HPC Fellowship!!

#ProudPI

25.11.2025 02:37 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Co-chairing the ACM/IEEE SC Technical Program with Martin Schulz this year was a great experience. Record submissions, an incredible committee who went above and beyond, and so many unforgettable moments. Can't wait for #SC26! See you all in Chicago!

#SC25 #HPC

25.11.2025 02:36 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Excited to share a new Communications of the ACM article highlighting our work on vascular digital twinsβ€”using millions of simulated heartbeats and wearable data to help predict heart issues long before symptoms appear. πŸ”—https://duke.is/cacm25

13.11.2025 21:30 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us tomorrow for Dr. Michael Rubinstein’s virtual talk, β€œThe Loops of Life.” Explore how molecular size, topology, and interactions shape polymers.

Register: duke.qualtrics.com/jfe/form/SV_...

@dukeengineering.bsky.social @dukeubme.bsky.social

06.11.2025 03:16 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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At the Center for Computational and Digital Health Innovation, we’re advancing technology with purpose.
Proud to spotlight Cameron Kim, who’s shaping the future of ethical digital health innovation and preparing the next generation of leaders.
comphealth.duke.edu/featured-res...

15.10.2025 16:02 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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So proud of the Randles Lab team for their fantastic presentations at #BMES2025β€”from cardiovascular digital twins and wearable-driven modeling to cellular biomechanics. Exciting to see their work pushing the boundaries of computational and digital health. #DukeBME #ProudPI

15.10.2025 13:52 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ§ͺI didn’t get to post about this earlier, but I recently had the honor of giving the opening keynote at IWOMP 2025. I had a great time talking with the MPI and OpenMP community about opportunities to bring HPC advances to health and scale vascular digital twins. #HPC #OpenMP #MPI #DigitalTwins

13.10.2025 17:24 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Taking the pulse on less computationally intensive cardiac digital twins Highly detailed simulations of the coronary artery only need one to two heartbeats to calibrate, rather than the standard five-plus

Led by Nusrat Sadia Khan, our team showed that cardiac digital twins can reach hemodynamic convergence in just 1–2 heartbeats, cutting computational costs and enabling real-time, scalable cardiovascular modeling.

Scilight: www.aip.org/scilights/ta...

Paper: pubs.aip.org/aip/pof/arti...

13.10.2025 17:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Great to join the 2nd Annual Duke Summit on AI for Health Innovation, hosted by @dukeaihealth.bsky.social, the Center for Computational and Digital Health Innovation, and DCRI.

Exciting discussions on AI, digital twins, and the future of healthcare. #AIforHealth #DigitalHealth #HPC #Innovation

13.10.2025 16:50 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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It’s #BMES2025! The Randles Lab is sharing new work on digital twins for heart failure, HRV-based model reduction, cellular heterogeneity, and APR modeling of RBC–cancer interactions. Stop by the Duke booth to learn about our Center for Computational and Digital Health Innovation! #DigitalHealth

08.10.2025 04:01 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Aristotle Martin Receives Honorable Mention for 2025 George Michael Memorial HPC Fellowship - Center for Computational and Digital Health Innovation Congratulations to Center member Aristotle Martin on receiving an honorable mention for the 2025 ACM-IEEE CS George Michael Memorial HPC Fellowships. The George Michael Memorial Fellowship honors exce...

Congrats to Randles Lab PhD student Aristotle Martin on being named an Honorable Mention for the ACM-IEEE CS George Michael Memorial HPC Fellowship! A well-deserved recognition of his innovative cancer cell modeling researchβ€”proud to see him celebrated.

comphealth.duke.edu/news/aristot...

02.10.2025 03:44 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks for having me! Had such a great time discussing HPC in Health with this community.

02.10.2025 03:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us Wed, Oct 2 @ 3 PM ET for the Center for Computational and Digital Health Innovation + Duke Quantitative Biodesign Virtual Seminar! Fabian Theis (Helmholtz Munich/TUM) will speak on β€œDecoding cellular systems.” All welcome. Register: duke.qualtrics.com/jfe/form/SV_...

02.10.2025 03:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Photon-Counting Computed Tomography for Evaluation of Coiled Intracranial Aneurysms BACKGROUND AND PURPOSE: Intracranial aneurysms treated with endovascular embolization often require surveillance imaging using digital subtraction angiography, an invasive, risky, and expensive proced...

πŸ§ͺOur new work in AJNR: Photon-counting CT + iMAR offers clear, non-invasive imaging of coiled intracranial aneurysmsβ€”showing promise as an alternative to invasive angiography.

Collab led by Brian Mac Grory with David Urick, Fides Schwartz, David Hasan & Evan Calabrese
πŸ”— www.ajnr.org/content/earl...

23.09.2025 15:32 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Full circle. From my first HLF as a student in 2013 ➑️ to giving a talk on stage as a laureate this year. Grateful for the journey and the community that made it possible. #HLF2025

18.09.2025 21:52 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Yesterday our Center hosted the first Espresso Chat β˜• with Jeff Hammond! He shared his path from quantum chemistry to #HPC and reminded students to lean into strengths, keep learning, and stay ahead of the curve. Favorite moment: a Valentine that read β€œJeff the Scientist.” #CareerJourney

12.09.2025 20:35 πŸ‘ 11 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We’re excited to welcome Leah Howell to the Randles Lab as a new graduate student in Biomedical Engineering!

Looking forward to all the discoveries aheadβ€”welcome to the team, Leah!

#RandlesLab #bme #dukebme #dukeuniversity

10.09.2025 16:14 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ§ͺπŸ‘©β€πŸ”¬Congrats to Wendy Wu on advancing to PhD Candidacy in Biomedical Engineering! Her work on computational models of cellular mechanics is pushing forward digital health innovation. Proud PI moment (yes, I was the one taking pics mid-exam). #WomenInSTEM #PhDCandidate

08.09.2025 15:08 πŸ‘ 9 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0