Jolene Sim

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New research calls an Alzheimer's protein "chameleon-like." 🦎 It shape-shifts to form toxic plaques, but this same flexibility also allows the plaques to break apart. onlinelibrary.wiley.com/doi/epdf/10.10…
#Alzheimers #amyloid #research #neuroscience #proteinfolding #dementia

A few old cassette tapes that list names of various Balkan music.

While I am a Japanese, #Balkan #music used to be my favorite, and I still have a collection of cassette tapes with Balkan #FolkSongs 😉
These tapes are about 35 years old, but today, I felt like revisiting my old collection 😊
I have always loved those unique, irregular rhythms, like 11/16 😉

People are walking around every day hanging on by a thread. Be king or be quiet.

Fact: 1 suicide death every 11 minutes

Fact: Many adults think about suicide or attempt suicide. 13.2 million seriously thought about suicide

You have no idea how close someone might be to giving up on life b/c of #hate

No person should wake up fearing they'll be targeted by hate

End. All. Hate.

Something to think about

WTAF?!

RIP to us all the next pandemic that hits us humans 😂 😂

RFK Jr.’s Prescription for Bird Flu on Farms: Let It Spread The health secretary has suggested allowing the virus to spread, so as to identify birds that may be immune. Such an experiment would be disastrous, scientists say.

www.nytimes.com/2025/03/18/h...

😂😂😂😂😂

So adorable! ❤️

Grey and white tuxedo fluffy cat with long whiskers has his mouth wide open and teeth showing, eyes closed

Thanks! Hopefully another year older another year wiser and all that good stuff

Thank you Berna! ❤️

Hearing about more dedicated public health professionals being let go and will re-iterate to any MD/DO with clinical interest in outpatient pediatrics HMU. We would be happy to have you.

Finally got all my vaccines updated! Having all three at one go is no fun.

If you see this, it’s a reminder for you to get all yours done too!

History of depression through the ages Depressive thoughts appeared from the origins of Humanity. They are found in philosophical writings and in literature since Antiquity. They have been approached in a religious or medical way since alw...

“Depressive thoughts appeared from the origins of Humanity. They are found in philosophical writings and in literature since Antiquity.”

www.neuroscigroup.us/articles/ADA...

Post-Prozac Nation (Published 2012) Just because the wonder drugs of the ’90s have disappointed doesn’t mean the science should be completely discarded. But it does mean we need a more sophisticated theory of depression.

Here is another interesting article from 2012 for additional reading:

www.nytimes.com/2012/04/22/m...

The History, Mechanism, and Use of Antidepressants: Understanding Treatments for Depression — Psychiatry & Psychotherapy Podcast Dr. David Puder and Dr. Michael Cummings explore antidepressants' history, mechanisms, and usage. Learn about the evolution from MAOIs to SSRIs, how these medications target neurotransmitter imbalance...

Quote from:

www.psychiatrypodcast.com/psychiatry-p....

RFK Jr. Goes After Widely Used Antidepressants, Claiming They Could Be A Threat To Americans The newly confirmed US Secretary of Health and Human Services has falsely stated that SSRIs are more addictive than heroin and contribute to school shootings.

I quote, “Prior to the discovery of antipsychotics and antidepressants, depressed and anxious patients were sent to restful places, or asylums. In the late 19th century, the number of asylums surged.” 1/2

www.vanityfair.com/news/story/r...

some patients experiencing post-viral fatigue may have an underlying CoQ10 deficiency, which CoQ10 supplementation may restore.” 4/4

will protect the enzymes of the MRC from reactive oxygen species-induced impairment. Interestingly, several clinical studies have demonstrated an association between decreased endogenous CoQ10 levels and an increased susceptibility to COVID-19 infection, and, consequently, … 3/4

… through its ability to restore electron flow in the mitochondrial respiratory chain (MRC), which will enhance ATP generation by oxidative phosphorylation. Furthermore, exogenous CoQ10 will also enhance mitochondrial antioxidant capacity, which… 2/4

Mitochondrial Dysfunction and Coenzyme Q10 Supplementation in Post-Viral Fatigue Syndrome: An Overview Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune disorders of unknown causes characterised by disabling post-exertional fatigue, myalgia and joint pain, cognitive imp...

Interesting study, any thoughts?

www.mdpi.com/1422-0067/25...

“CoQ10 supplementation may ameliorate mitochondrial dysfunction and alleviate fatigue associated with Post Viral Fatigue Syndrome …” 1/4

I have one that bit me after I told her there wasn’t any more bacon but she heard me crunch. 😂 should’ve seen her eyes when she heard the crunch!

Trump administration layoffs set to hit NIH are ‘devastating,’ former director Monica Bertagnolli says Sweeping layoffs are set to hit federal health and science agencies, including at the NIH, and former director Monica Bertagnolli called the situation at the NIH “devastating.”

The former NIH director speaks out. www.statnews.com/2025/02/16/n...

Your friendly neighborhood librarian here...buy physical copies of your favorite books, especially challenged or banned books. Preferably from small local merchants. That's all; carry on. #Read #BookSky #Resist 📚

Black and white cat like a dairy cow posing on a white furry carpet

Introducing Pan, sorry we are late for #caturday!

All that effort, time, and money down the drain.

CDC cuts expected to devastate Epidemic Intelligence Service, a ‘crown jewel’ of public health Members of the CDC's Epidemic Intelligence Service were warned Friday that many of them were about to be fired

Make no mistake. This is an all-out attack on health in America.

Not only is the EIS vital to controlling infectious disease; it was where a remarkably high fraction of our public health leaders received formative training and experience.

www.statnews.com/2025/02/14/t...

These magnificent whiskers make my day ❤️