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Tajbakhsh Lab

@tajbakhshlab

The Tajbakhsh laboratory works on skeletal muscle development, homeostasis, regeneration and ageing, with particular focus on muscle stem cells.

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25.01.2025
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Latest posts by Tajbakhsh Lab @tajbakhshlab

Our 2021-2022 ASCB participants are now part of a worldwide research network.
@tajbakhshlab.bsky.social
@zenlabpasteur.bsky.social
@devstempasteur.bsky.social
@stemdevevo.bsky.social
@pasteuredu.bsky.social

27.02.2026 09:05 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

First dynamic in vivo analysis of dystrophic MuSCs. Identifies niche dysfunctions and points to strategies to restore stem cell function in DMD.

21.02.2026 13:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Cross-grafting experiments uncouple MuSC behaviours: Migration is dictated by the myofibre niche, fate decisions are fibre-independent, and symmetric cell divisions are disrupted. Resolves some long-standing debates in the field.

21.02.2026 13:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

mdx stem cell dysfunction is driven by p38/PI3K signalling, unlike healthy MuSCs, leading to precocious differentiation and loss of stemness.

21.02.2026 13:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

21.02.2026 13:05 πŸ‘ 19 πŸ” 11 πŸ’¬ 1 πŸ“Œ 1

This two-week course combines lectures and practical sessions that incorporate leading edge technologies to address questions in stem cell biology in the context of organogenesis and regeneration in different organisms.
@tajbakhshlab.bsky.social
@zenlabpasteur.bsky.social @stemdevevo.bsky.social

23.01.2026 17:55 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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🎊 Happy 2026 from #ASCBcourse!
Thanks to all former participants, speakers & future applicants! πŸ™
One highlight: tracking stem cell-like behaviors in chick embryos during #gastrulation 🐣
Apply now πŸ‘‰ shorturl.at/PyUHi
πŸ“† June 22-July 3 @institutpasteur
#StemCells
@tajbakhshlab.bsky.social

02.01.2026 09:31 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Great project!

19.12.2025 07:25 πŸ‘ 0 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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🚨 JOB OFFER in our lab at Institut Pasteur 🚨
We are looking for a research technician! Please repost πŸ™

18.12.2025 10:39 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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✨ The stunning image on our flyer isn't just beautifulβ€”it's cutting-edge #stemcell #research!

Learn similar techniques at ASCB 2026 with
@tajbakhshlab.bsky.social
@zenlabpasteur.bsky.social
@stemdevevo.bsky.social

πŸ“† June 22-July 3 | Paris
@pasteuredu.bsky.social

Apply πŸ‘‰ shorturl.at/PyUHi

05.12.2025 13:05 πŸ‘ 2 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

This two-week course combines lectures and practical sessions on leading edge technologies and questions in Stem Cell Biology.
@tajbakhshlab.bsky.social @zenlabpasteur.bsky.social @devstempasteur.bsky.social @stemdevevo.bsky.social @cedric-blanpain.bsky.social

24.11.2025 11:42 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

β€ͺAnother round of learning with great, dedicated, instructors and practical training covering multiple organisms and tissues!‬

24.11.2025 14:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ”¬ Don’t miss the 7th Annual FSSCR Meeting in Lyon!
✨ #StemCells research & future clinical applications.
πŸ“† Register by 19 Oct 2025 for regular rates πŸ‘‰ fsscr-meeting.org #FSSCR2025 β€ͺ@fsscr.bsky.social‬‬

16.09.2025 13:44 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1

Thirst for knowledge?

The 2025 Stem Cell Summer School starts next Friday! We have an uncommonly spectacular array of faculty, and have no doubt that our delegates will also be spectacular

Follow β€ͺ@stemcellsummer.bsky.social‬ and #SCSS2025 for updates during the meeting

07.09.2025 11:18 πŸ‘ 13 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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FSSCR ANNUAL MEETING French Society on Stem Cell Research (FSSCR)

Still time to register for the 7th Annual FSSCR Meeting in Lyon and experience pioneering research in #stemcells biology & future clinical applications!
πŸ“† Regular rates available until 19 Oct 2025
πŸ‘‰https://buff.ly/BF2PGOF
@FSSCR_officiel
#FSSCR2025

05.09.2025 13:03 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

⏳ Still time to register + submit your poster abstract

πŸ—“οΈ Deadline: Sept 19!

05.09.2025 14:48 πŸ‘ 4 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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πŸ”¬ Don’t miss the 7th Annual FSSCR Meeting in Lyon!
✨ #StemCells research & future clinical applications.
πŸ“† Register by 19 Oct 2025 for regular rates πŸ‘‰ fsscr-meeting.org #FSSCR2025
@fsscr.bsky.social‬

01.09.2025 12:43 πŸ‘ 7 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1

Bravo!

31.08.2025 10:12 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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RΓ©mi Mounier, BΓ©nΓ©dicte Chazaud @benchazaud.bsky.social ‬ @inserm.fr at UniversitΓ© Claude Bernard Lyon and co-workers show that immune #aging impairs #muscle #regeneration via #macrophage-derived anti-oxidant selenoprotein P.

-> www.embopress.org/doi/full/10....

19.07.2025 08:18 πŸ‘ 12 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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and picnic-ing...

29.06.2025 19:24 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Relaxing on the rooftop, an evening picnic with students and instructors

29.06.2025 19:24 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Taking us through axial elongation is David Turner @gastruloids.bsky.social, a great teacher of ES cell handling and formulating protocols for reproducible gastruloid generation. A-P extension, and into the 2nd week.

29.06.2025 19:24 πŸ‘ 5 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Superb dual lectures by @amartinezarias.bsky.social
on mouse, human, multispecies, embryology, gastruloids; from bench to birth - discussions on the dynamic nature of the field. Importance of history, context, and remaining lucid while discovering. Much to reflect upon, as we explore.

29.06.2025 19:24 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Isolation of muscle fibres and their stem (satellite) cells. Plate and wait, from quiescence to differentiation - following Shahragim’s lecture on muscle stem cell emergence and diversity. @tajbakhshlab.bsky.social,
@brendan-evano.bsky.social, Barbara Gayraud-Morel. Patience is a virtue.

29.06.2025 19:24 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Laura Cantini & Stephan Fisher lectures guided us through the trials and tribulations of omics - the power and drawbacks of data integration, and how to navigate the minefield. Thanks!

29.06.2025 19:24 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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1st week ends with: a swim in the zebrafish brain - cool genetic tracing of neural stem cells with @zenlabpasteur.bsky.social, Laure Bally-Cuif, Sara Ortica, Tanya Foley, Isabelle Foucherβ€”lots covered in a condensed period.

29.06.2025 19:24 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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and picnic-ing...

29.06.2025 19:24 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Post image Post image Post image Post image

Relaxing on the rooftop, an evening picnic with students and instructors

29.06.2025 19:24 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Post image Post image

Taking us through axial elongation is David Turner @gastruloids.bsky.social, a great teacher of ES cell handling and formulating protocols for reproducible gastruloid generation. A-P extension, and into the 2nd week.

29.06.2025 19:24 πŸ‘ 5 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Superb dual lectures by @amartinezarias.bsky.social
on mouse, human, multispecies, embryology, gastruloids; from bench to birth - discussions on the dynamic nature of the field. Importance of history, context, and remaining lucid while discovering. Much to reflect upon, as we explore.

29.06.2025 19:24 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0