@powrielab
Powrie Lab news and Mucosal Immunology content! Based at the Kennedy Institute of Rheumatology @kiroxford.bsky.social Posts are by members of the Powrie Lab, not necessarily representative of the lab as a whole.
We had a great time at the annual Kennedy Network Conference in Birmingham last week! We really enjoyed the chance to listen to some excellent keynote talks, present some of our own work, and hear what the wider network is up to! Looking forward to next year already🌸🌼
@kiroxford.bsky.social
Primary schools, join us for #BritishScienceWeek 💩
Oxford poo scientists have created a free Poo Trivia Quiz for KS1 and KS2. Designed with Guts UK and sponsored by Wooclap "helps people teach and learn".
Online, ready to use, no prep required.
Register here: forms.office.com/e/RxJCUVsqYK
We’re really pleased to share that our excellent DPhil student, Amit, successfully defended his PhD thesis last week! We had a great time celebrating with you and look forward to seeing what your next chapter holds!🎉🧑💻🥂
@kiroxford.bsky.social
@amit-halkhoree.bsky.social @nickilott.bsky.social
☕Borsa et al. show that asymmetric #Tcell division after activation requires #autophagy to promote #mitochondria turnover, with T cells inheriting older mitochondria showing decreased degradation, reduced memory potential and altered metabolism.
bit.ly/458ODgL
Celebrating #February11 by highlighting Professor Claudia Mauri, the Editor‑in‑Chief of @ceijournal.bsky.social Her leadership and expertise continue to shape the future of immunology.
Read the interview on the BSI website here: https://bit.ly/4abuedR
#WomenInScience
This #February11 we are celebrating Prof Jessica Teeling, winner of the BSI Public Engagement Award! Her grant‑supported “Snakes and Letters for a Healthy Brain” project is inspiring conversations on dementia risk + immunity. #WomenInScience
Read here: https://bit.ly/3Ktiito
Marking #February11 by celebrating Professor Tracy Hussell, BSI President, and her Nature Mentoring Award for Lifetime Achievement.
A great recognition of her commitment to supporting early career researchers and strengthening the immunology community.
#WomenInScience #Immunology
Congratulations to the wonderful Natasha for successfully defending her DPhil thesis! We’re excited to see what comes next for Natasha and her MAIT cell story whilst she continues her project as a postdoctoral researcher🥳👩🔬
@kiroxford.bsky.social
New year, new paper! Thrilled to share that our review “Contextualising TH17 cells in cancer” is out now!
Congratulations to Declan & team for a fantastic, in depth overview🥳
Go give it a read here:
doi.org/10.1038/s415...
@natrevimmunol.nature.com
@kiroxford.bsky.social
Last night was our Lab Christmas party! Special thanks to Claire and Nick for organising some excellent party games for us (guessing the flavour of Skittles whilst blindfolded is much harder than you’d think!) and to Branca for hosting us🎅🎄🌟
@kiroxford.bsky.social
@nickilott.bsky.social
An excellent opportunity, please have a look at the position below!🧫👩🔬
We’re hiring! Two postdoctoral research positions are available in our lab - one in mucosal immunology, and one in exposome immunology (MRC CoRE)! Apply by December 22nd!🎄
Position 1: tinyurl.com/2mh44tn4
Position 2: tinyurl.com/5ffzxsfb
@kiroxford.bsky.social @exposomeimmunology.bsky.social
Congratulations to our fantastic DPhil student, Henry, for defending his PhD thesis today!! It’s been a pleasure to have Henry in the lab & we miss him already! Go check out the review (linked below) if you’d like to see some of his work🥳🧑🔬
@kiroxford.bsky.social
pubmed.ncbi.nlm.nih.gov/40252635/
We’re very proud of our very own Dr Alice Bertocchi for winning a Kennedy Trust Transition Fellowship! Keep up the amazing work as always, Ali!🥳❤️
We are hiring a Postdoctoral Research Assistant to study how microbiomes influence barrier biology and shape responses to viral infection!
This post is part of the exciting new MRC CoRE in Exposome Immunology.
Apply by December 18 👇
www.kennedy.ox.ac.uk/jobs/postdoc...
Day 4 and the final day of the BSI saw a fantastic talk from @labliston.bsky.social about Tregs in the brain and an excellent session devoted to “Barriers, bugs, and breakdowns” - right up our street! Thank you to all organisers and presenters @britsocimm.bsky.social for a great week in Liverpool🫶
Day 3 of the BSI was a busy one, with Yuqing & Dehui presenting posters, and Ffion giving an excellent talk all about AMR Klebsiella dynamics in the gut! It was also great to see Dave Withers give a fantastic plenary talk!🧫🧬
@dehuic.bsky.social @yuqinglong.bsky.social
@witherslab.bsky.social
Day 2 of the BSI saw Gemma & Rachel from the lab presenting posters, as well as the lovely Anna Ahlback from the Maloy lab delivering a great talk on Hh infection and its impact on DSS colitis (go check out their new preprint!)👩🔬
@gemmala.bsky.social @rachelanscombe.bsky.social @aahlback.bsky.social
Day 1 of the BSI 2025 on Monday saw the wonderful Judi Allen deliver a fabulous keynote talk! We were also very excited to see Judi share the news of our new MRC Exposome Immunology Manchester/Oxford collaboration👩🔬
@profjudiallen.bsky.social
@exposomeimmunology.bsky.social
@britsocimm.bsky.social
Delighted to share that Fiona was awarded the FSI EFIS-IL Lecture Award last week as a keynote speaker at the 56th Annual Meeting of the French Society for Immunology! We’d like to warmly thank the SFI for the award, it was a pleasure to attend!🇫🇷👩🔬
@sfi-immunologie.bsky.social @kiroxford.bsky.social
We’re thrilled to share that we’re part of the Experimental Medicine Collaboration (EMC) with GSK! The EMC will put translational science at the forefront of developing treatments for immune mediated inflammatory diseases👩🔬🧬🧫
www.ox.ac.uk/news/2025-11...
@gsk.bsky.social @kiroxford.bsky.social
Some pics from our annual lab autumn walk! We went to the lovely Blenheim palace to get some steps in & enjoy the autumn leaves🍁🚶♀️🌳
A great afternoon celebrating the award of our MRC CoRE in person. We heard about projects spanning our discovery pipeline, from ExWAS and mechanistic barrier immunology, to potential therapeutic angles for IBD and machine learning for diagnostics.
#exposome #immunology
@kiroxford.bsky.social @ndorms.bsky.social
Interested in joining the Powrie Lab? We’re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. You’ll be part of our new MRC CoRE in Exposome Immunology!🧫🦠
Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
@kiroxford.bsky.social @ndorms.bsky.social
Throwing it back a few weeks to the final meeting of the CRUK grand challenges optimisticc study! We had a great time in Boston discussing progress in the colorectal cancer & microbiome field - it’s been a real pleasure being part of this group!🧫🫶
@elayton13.bsky.social
We’re delighted to hear that our favourite cell type (Regulatory T cells!) have been recognised in the Nobel Prize this year! Huge congratulations to Mary, Fred, and Shimon for their pivotal work in the field & here’s to many exciting Treg advances to come!🥳👏🎉
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...