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Centre for Structural Systems Biology CSSB

@cssbhamburg

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18.11.2024
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Latest posts by Centre for Structural Systems Biology CSSB @cssbhamburg

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Today’s CSSB @cssbhamburg.bsky.social Seminar Series featured Paul Guichard @centriolelab.bsky.social from Geneva who shared their beautiful discoveries of the centriole assembly, conoid molecular architecture, and the connecting cilium of the eye! ♡ 🫧 @uni-hamburg.de

23.02.2026 16:21 👍 3 🔁 1 💬 0 📌 0

Such a fun collaboration with @mel-foulon.bsky.social from the TS lab 🤝-👀 We combined dual RNA-Seq 🧬 and advanced imaging 🔬 to uncover how intracellular compartmentalization drives niche-specific metabolic phenotypes in mycobacteria!!
Fantastic team effort ✨
#Tbsky #microsky

12.02.2026 12:00 👍 12 🔁 8 💬 3 📌 0
Course 'Ion trap and advanced MS techniques' - group picture at MS Vision

Course 'Ion trap and advanced MS techniques' - group picture at MS Vision

The year has just started, a lot already happened at SPIDocs!
🎉Charlotte Uetrecht - new Scientific Director @cssbhamburg.bsky.social
🚀Secondments at @uppsalauniversity.bsky.social and Fasmatech Science and Technology
🚀Internships at SLAC
✨Course 'Ion trap and advanced MS techniques' at MSVision

19.02.2026 11:23 👍 1 🔁 1 💬 0 📌 0

New preprint from @carobarisch.bsky.social lab!

12.02.2026 11:43 👍 3 🔁 0 💬 0 📌 0
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@mariarosenthal.bsky.social
#STEM #GirlsInScience

11.02.2026 11:04 👍 4 🔁 1 💬 0 📌 0
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11.02.2026 11:04 👍 2 🔁 1 💬 1 📌 0
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🎉 Happy International Day of Women and Girls in Science 🔬

Some of our group leaders shared insights into what they love most about their jobs in science. ❤️

CSSB supports women and girls in science through initiatives like Girls‘ and Boys‘ Day.

#WomenInScience @landaulabcssb.bsky.social

11.02.2026 11:04 👍 9 🔁 5 💬 1 📌 0

Integrated structural biology at its best with fantastic talks in cryo-EM, NMR, and X-ray techniques
Also integration with other Instruct Centres, in this case Kay Grünewald Instruct-DE @cssbhamburg.bsky.social 'Conformational flexibility and molecular plasticity in herpesvirus entry and egress'

29.01.2026 16:48 👍 7 🔁 5 💬 0 📌 0
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New protocol out now! 📕🖊️🔍

A practical workflow for analyzing CD thermal unfolding of short RNAs — from SVD decomposition to two-state fitting to extract melting temp and enthalpy with ChiraKit.

A must-see if you’re working with RNA structure and CD data.

DOI: 10.1007/978-1-0716-5084-4_12 

29.01.2026 15:22 👍 6 🔁 2 💬 1 📌 0

My colleagues have put together a nice book chapter on amyloid polymorphism. Have a look! 🧪🧬🧶
#amyloids #cryoem @landaulabcssb.bsky.social @meytallandau.bsky.social @cssbhamburg.bsky.social @stratifa.bsky.social

21.01.2026 14:37 👍 7 🔁 5 💬 0 📌 0
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Fun in the snow!

09.01.2026 13:32 👍 6 🔁 1 💬 0 📌 0
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New Year, New Leadership!

Charlotte Uetrecht is the new Scientific Director of CSSB. Holger Sondermann and Tim Gilberger are Deputy Directors.

Find out more: t1p.de/q6mdg

@carobarisch.bsky.social @topf-lab.bsky.social @landaulabcssb.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social

05.01.2026 14:32 👍 8 🔁 2 💬 0 📌 0
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Wishing you peace, joy and happiness this holiday season. Looking forward to 2026!

@leibnizliv.bsky.social @fzborstel.bsky.social @helmholtzhzi.bsky.social @embl.org @uni-hamburg.de

18.12.2025 10:43 👍 10 🔁 2 💬 0 📌 0
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The 25th issue of our CSSB Connect newsletter is here!

Find out what's been going on at CSSB during the second half of 2025.

t1p.de/352cr

@uni-hamburg.de @leibnizliv.bsky.social @fzborstel.bsky.social @helmholtzhzi.bsky.social @embl.org

16.12.2025 08:37 👍 6 🔁 1 💬 0 📌 0
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Our next CSSB Connect newsletter is coming out soon!

Make sure it's delivered straight to your inbox by signing up today: t1p.de/hnamq

@landaulabcssb.bsky.social @carobarisch.bsky.social @bosse-lab.bsky.social @topf-lab.bsky.social @jankosinski.bsky.social

12.12.2025 10:13 👍 2 🔁 1 💬 0 📌 0

Congratulations Julia!

11.12.2025 13:02 👍 5 🔁 2 💬 0 📌 0
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Congrats to Thomas Mulvaney from the @topf-lab.bsky.social for his Nomination for the Leibniz Association’s Dissertation Award — a great recognition of his innovative work on integrative modeling of proteins and nucleic acids. #ResearchExcellence

@leibnizliv.bsky.social
@cssbhamburg.bsky.social

05.12.2025 16:02 👍 7 🔁 2 💬 0 📌 0
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MHH invites applications for a W1 university professorship for Systems Virology at CSSB. The research focus should be on analyzing viral infections using innovative, systemwide methods to elucidate virus-virus and virus-host interaction networks.

More info: t1p.de/nag2v

@bosse-lab.bsky.social

03.12.2025 11:16 👍 4 🔁 4 💬 1 📌 0
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CSSB group leader Jens Bosse @bosse-lab.bsky.social @resist-cluster.bsky.social and CSSB associate member Chris Meier @uni-hamburg.de , together with Hans-Achim Wagenknecht from the Karlsruhe Institute of Technology, have developed a new method for live-cell RNA imaging

Find out more: t1p.de/18suk

01.12.2025 12:08 👍 3 🔁 1 💬 0 📌 0
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The Krey lab is hiring! If you are interested in viral glycoproteins, neutralizing antibodies and vaccines - and you want to further study this using structural and biochemical approaches, please apply!
stellenangebote.uni-luebeck.de/jobposting/d...

01.12.2025 09:04 👍 1 🔁 1 💬 0 📌 0
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Join CSSB! The Sondermann lab is interested in deciphering the molecular processes that determine bacterial interactions in microbial communities. They are looking for a PhD candidate to investigate the bacterial secretion systems involved in these processes.

Apply now: v22.desy.de/e67416/recor...

28.11.2025 14:12 👍 9 🔁 6 💬 1 📌 0
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An international research team headed by the Bozdech lab at the Nanyang Technological University and the Gilberger lab (BNITM @uni-hamburg.de) at CSSB reveals the global landscape of protein-protein interactions that govern the biology of the malaria parasite.

Find out more: t1p.de/puyln

28.11.2025 10:53 👍 5 🔁 3 💬 0 📌 0
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Researchers from @topf-lab.bsky.social, @embl.org, and IIT have visualised how a large RNA molecule assembles itself into a functional machine, revealing a dynamic choreography that helps us better understand structural folding and misfolding, almost frame by frame.

More information: t1p.de/tt2hk

27.11.2025 11:46 👍 1 🔁 0 💬 0 📌 1
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📣Join us on December 9 for the Academia-Industry Matchmaking Workshop, focused on innovative solutions for challenges in the Life Sciences.

Registration: indico.desy.de/event/50931/

@landaulabcssb.bsky.social @leibnizliv.bsky.social @uni-hamburg.de @fzborstel.bsky.social

27.11.2025 09:55 👍 3 🔁 1 💬 0 📌 0
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Using a combination of X-ray crystallography and cryo-EM, a new study from @landaulabcssb.bsky.social shows that amyloids,form different structures that could be useful as a natural mechanism of immune protection.

More info: t1p.de/4n8se

@amyloid-sam.bsky.social @emilgustavsson.bsky.social

26.11.2025 14:15 👍 10 🔁 4 💬 0 📌 0
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The Barisch lab held a 2 week practical module called 'Molecular Master Thieves' including an excursion to FZB. It was amazing & inspiring to see the students' enthusiasm & curiosity.

We wish you all the best for your bright careers!
@carobarisch.bsky.social @fzborstel.bsky.social @uni-hamburg.de

24.11.2025 12:32 👍 4 🔁 2 💬 0 📌 0
Preview
Clathrin adaptors drive phase separation in endocytosis and trafficking Liquid-liquid phase separation (LLPS) underlies the formation of biomolecular condensates that organize cellular processes, including endocytosis and membrane trafficking. Although LLPS has been impli...

New preprint out!📃

This work uncovers how the clathrin adaptors Ent5 & Sla2
undergo LLPS, revealing distinct structural drivers that shape endocytic and trafficking dynamics.

@lucasdefelipe.bsky.social @katharinchen.bsky.social @embl.org @cssbhamburg.bsky.social

👉 www.biorxiv.org/content/10.1...

21.11.2025 10:13 👍 12 🔁 6 💬 0 📌 0
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On Wednesday afternoon, students who are part of DESY's ELB-Akademie programme visited CSSB. The students learned about our molecular infection research and visited the @landaulabcssb.bsky.social and our ALFM and cryo-EM facilities.

Find out more about the ELB-Akademie: t1p.de/w89j6

21.11.2025 09:32 👍 5 🔁 3 💬 0 📌 0
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Congratulations to the Hamburg iGEM team for winning a gold medal in Paris for their project DeathCapTrap. @uni-hamburg.de @igemhq.bsky.social @igemcommunity.bsky.social

Find out more: t1p.de/dtho1

20.11.2025 12:23 👍 6 🔁 2 💬 0 📌 0

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

18.11.2025 10:18 👍 52 🔁 40 💬 0 📌 0