Wes Rogers

Exclusive | FDA’s Controversial Vaccines Chief Will Leave the Agency Dr. Vinay Prasad will depart in April, after a year leading the division that approves vaccines and biotech drugs.

www.wsj.com/health/healt... #IDSky

Reports of organ donor–derived Kaposi sarcoma–associated herpesvirus among transplant recipients (n = 46) and investigation of additional recipients* — United States, January 2021–September 2025. * Retrospective KSHV testing of the 46 donors whose organs were associated with posttransplant donor organ KSHV infection identified 25 (54%) who received positive results and four (9%) who received negative results; organs from 17 (37%) donors had not been tested.

Number of reports of suspected organ donor–derived Kaposi sarcoma–associated herpesvirus infections in transplant recipients (N = 57) — United States, January 2010–September 2025

Kaposi Sarcoma–Associated Herpesvirus Infection and Complications Among Solid Organ Transplant Recipients — United States, January 2021–September 2025

New in MMWR

-46 cases of susp donor-derived KS in SOT, vs 9 from 2016–2020
-2/3 donors had a hx of nonmedical drug use

www.cdc.gov/mmwr/volumes...

Just woke up and checked emails to see that 8 new participants recruited to #SNAP_Trial in the past 8 hours! While a number of domains have closed (PSSA, MSSA, adjunctive clindamycin) we continue to recruit to other domains. Beyond 5,800 total participants now.
@gurujosh.bsky.social

The Clinical Impact of Antibiotic Allergy Labels on One‐Year Outcomes of Solid Organ Transplant Recipients Antibiotic allergy labels (AALs) are common and often incorrect. They have many potential impacts, including the use of broader-spectrum antibiotics and suboptimal treatment of infections. The impact....

New research from our faculty: antibiotic allergy labels in transplant patients are linked to C. diff infections, more antibiotic use & longer hospital stays, and they may be preventable. 🔬 #IDSky #MedSky

New in ICHE: Not everyone is "special" 🦠

Free text overrides in UA driven reflex urine culture protocols are frequently misused
▶️ 97% (816/839) of "other" indications inappropriate & 83% cultures were avoidable
▶️Removing the option: low-risk, high-yield

#IDSky

📄: doi.org/10.1017/ice.2026.10419

$5 million boost for world-first trial tackling strep infections in both children and adults - Doherty Institute A major new clinical trial, the Streptococcal Adaptive Platform (STRAP), has received $5 million in funding from the Australian Government’s Medical Research Future Fund (MRFF) to improve treatment for life-threatening streptococcal infections across all age groups. Lead by researchers and clinicians from the Doherty Institute, Murdoch Children's Research Institute (MCRI), and other national and international partners.

Every retrospective IVIG publication ends the same. Your chance to change that conclusion coming soon… STRAP in, STRAP is coming!

www.doherty.edu.au/articles/wor...

@steventong.bsky.social @gurujosh.bsky.social @drmichaelmarks.bsky.social @drtoddlee.bsky.social @ashabowen.bsky.social and more!

Intravenous immunoglobulin treatment in patients with streptococcal toxic shock syndrome in southern Sweden – A retrospective population-based study In this retrospective study of 106 patients with streptococcal toxic shock syndrome, the results regarding the benefit of intravenous immunoglobulin were i

Should we use IVIG in Strep Toxic Shock Syndrome?

New multi-center 🇸🇪 study:

-106 pts (53% treated w/ IVIG)

-In model accounting for (lactate, SOFA score, CCI and clindamycin use, and immortal time bias 😍) showed no benefit HR 0.69, 95% CI: 0.34–1.41

#IDSky

academic.oup.com/ofid/advance...

That's crazy!

Well they presented a lot of prelim data at ESCMID

Could do a combo SNAP and CloCeBa?

They went to war with Iran (which nobody in America was asking for) so they could conjure an excuse to allow ICE to keep murdering Americans and teargassing schools here at home with impunity (which nobody in America was asking for).

"American innovation" now refers to making a kind of atrocity cronut by combining insider trading with war crimes.

When I saw the news story about the girls school being bombed, one of my first thoughts was about how unlike American physics, Iranian physics is 50% women at the undergrad level and how some of those girls who had been murdered were going to be physicists one day

The number of dead kids in the Israeli bombing of a girl’s school in Minab, southern Iran, has now reached 148.

Don’t let them sell you dead children as “collateral damage of a just war”. The death of Khamenei does not justify 148 dead children.

At least 148 dead after reported strike on school, Iran says Iran has blamed the US and Israel for the strike; the US is looking into reports of the incident, while the IDF says it is

The mass murder of civilians in Gaza, the brazen attacks on hospitals and schools, without any accountability has created a new kind of warfare that should terrify and enrage all of us.

Every child lost is someone’s whole world. Every life lost matters www.bbc.co.uk/news/article...

“Fish start to stink at the top”: [this is a proverb] applied to people who have scoundrels for leaders.”

᾿Ιχθὺς ἐκ τῆς κεφαλῆς ὄζειν ἄρχεται: ἐπὶ τῶν ἐπιστάτας φαύλους ἐχόντων. #Proverb

the war is unpopular but it's also illegal but it also doesn't serve any purpose but it also undermines diplomacy but it also is set to produce the opposite outcome as intended but it also already has hundreds dead and threatens more but it also will not make anything better for anyone but it also

I was born in an Iranian prison. My parents were held in their jails. My uncles lie in their mass graves. Nothing you can tell me about the crimes of the Iranian regime that I haven't lived in blood and bone. That doesn't mean I want my people bombed, maimed, killed, their homes in ruins. If your vision of liberation comes only through the destruction of innocent lives, then it's not freedom you're after. Sahar Delijani, Iranian author

I am pro Iranian people. I stand with them against their own government’s repression AND against the imperial violence in the form of bombs dropped from the sky from Israel & the US who have already killed hundreds.

I support neither imperialism or dictatorship.

Sahar Delijani said it best:

Couldn't happen to a nicer guy

Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...

🔥Just published 🔥
TAPER-V RCT
In this RCT of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to a standard 2-week pulse regimen in patients a first episode or first recurrence of CDI
Vanco for 10d is obsolete! #IDSky #EMIMCC
jamanetwork.com/journals/jam...

White House to pause $259M in Minnesota Medicaid dollars in fraud crackdown It’s the latest in a growing list of fraud-focused threats and probes from the Trump administration.

This is about political retribution.

Trump is weaponizing the federal government to punish states like Minnesota that didn’t vote for him — ripping away funds from pregnant women, seniors, and people with disabilities.

You don’t fight “fraud” by hurting the most vulnerable.

This Startup is Trying to Harvest My Bones for Gelatin. The Difference? They’re Doing It Humanely.

Florida uses emergency rule to cut patients off AIDS medication The state filed the changes the day before a legal hearing with the AIDS Healthcare Foundation.

"Emergency" rule means 1000s of Floridians will lose access HIV/AIDS medications March 1. Ladapo said the move was needed to fill a budget shortfall made worse by expiring premium tax credits. No other state has made such a drastic change.

#IDsky #publichealth #LGBTQ #Florida #politics

Have to admit that I had not heard of pseudorabies before

#IDSky

#croi2026 #hivsky #idsky 513 - Phase III Efficacy and Safety of Switch From B/F/TAF to Single-Tablet BIC/LEN in #ARTISTRY-2
presented by Eric Meissner: BIC/LEN maintained high levels of virologic suppression at week48 & non-inferior to B/F/TAF

Some day we'll all regret this & we'll hold hearings & rend garments & pledge "never again" & we'll be just as full of shit as we were last time.

Disconcerting to see such low performance of Legionella urine Ag in a sick population.

Reinforces my strategy that if a patient is sick enough, may not discontinue Legionella coverage just for a negative urine antigen.

More than 75,000 Post readers cancelled their subscriptions after the recent cuts. An even larger number bailed after Bezos killed the endorsement of Harris, but now the decline feels terminal. Bezos does not want a great paper with a conservative opinion page (like the Wall Street Journal). He seemingly barely wants a paper at all, treating one of the most important American media institutions like an embarrassing child from a previous marriage that no longer fits his lifestyle.

This sounds unbelievable but its true: since Bezos acquired The Post, his wealth has grown tenfold and the Post has been cut in half.
donmoynihan.substack.com/p/the-trust-...

COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium COVID-19 vaccination with a booster reduces the odds of PE by 30% approaching 60% reduction among women with pre-existing morbidities.

Remember when RFK Jr. unilaterally decided that COVID19 vaccines should no longer be recommended during pregnancy?

Well, COVID19 increases the risk of preeclampsia.

And it turns out that getting boosted, either before or during pregnancy, significantly reduces the risk of preeclampsia.

Key take-aways:
There are lots of insights here for how to diagnose and manage resistance more effectively… but most important #1 for chronic infections is finding out if resistance is there BEFORE you start to treat! - doable, cheap, likely to delay resistance

www.biorxiv.org/content/10.6...