Check out this stellar work by Bohra and Mazumdar @tifrhyderabad.bsky.social π π
08.01.2026 04:13
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Check out this stellar work by Bohra and Mazumdar @tifrhyderabad.bsky.social π π
Nucleolar reorganization on stress depends on physicochemical changes due to nascent rRNA synthesis https://www.biorxiv.org/content/10.64898/2026.01.03.697456v1
Glad to share our latest work that came out recently. We dive into the mechanisms of how Transcription Factors (TFs) like the nuclear receptor, ERΞ± navigate the genome to find their targets.
Congratulations ππ
Thank you, DBT/WT India Alliance, for highlighting our work in the #IntracellularCommunication series. Truly grateful for the incredible support that has enabled us to explore lysosomal mechanosensing and collective cell migration. π¬β¨
Do check out the article.
www.linkedin.com/posts/indiaa...
Next, Tamal Das @tifr.res.in revealed the influence of lysosomes in leader cell formation and the ER in supporting lamellipodial crawling and purse-string contraction, identifying them as key integrators of mechanochemical cues to drive collective cell migration. #MBIMPG2025
π«NEW: Das, @fabianspill.bsky.social & co combine intracellular cartography and biophysical modelling to reveal how edge curvature governs endoplasmic reticulum (ER) morphology, showing that curvature-dependent ER reorganization directs distinct modes of epithelial cell migration.
bit.ly/3HFAQ8S
Fresh off the press: Simran Rawal (Graduate student, Tamal Das's lab, TIFR Hyd) & colleagues find out how organelles inside epithelial cells (lining a wound) reorganise themselves & opt for specific known migratory modes in response to different curvatures of wounds.
www.nature.com/articles/s41...